Basic and escalating immunomodulatory treatments in multiple sclerosis: Current therapeutic recommendations

2008 ◽  
Vol 255 (10) ◽  
pp. 1449-1463 ◽  
Author(s):  
◽  
H. Wiendl ◽  
K. V. Toyka ◽  
P. Rieckmann ◽  
R. Gold ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Therapeutic Recommendations

scholarly journals The Impact of Motor Disability and the Level of Fatigue on Adherence to Therapeutic Recommendations in Patients with Multiple Sclerosis Treated with Immunomodulation

2021 ◽  
Vol 18 (15) ◽  
pp. 3609-3614
Author(s):  
Robert Ślusarz ◽  
Joanna Olkiewicz ◽  
Robert Bonek ◽  
Karolina Filipska ◽  
Monika Biercewicz ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Motor Disability ◽  
Therapeutic Recommendations ◽  
The Impact

scholarly journals Optimizing outcomes in multiple sclerosis: consensus guidelines for the diagnosis and treatment of multiple sclerosis in Latin America

2011 ◽  
Vol 4 (6) ◽  
pp. 349-360 ◽  
Author(s):  
Adriana Carrá ◽  
Miguel Ángel Macías-Islas ◽  
Alberto Alan Gabbai ◽  
Jorge Correale ◽  
Carlos Bolaña ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Latin America ◽  
Latin American ◽  
Online Survey ◽  
Cost Effective ◽  
Differential Diagnoses ◽  
Effective Control ◽  
Therapeutic Recommendations ◽  
Latin American Countries

Objective: The prevalence of multiple sclerosis (MS) in Latin America varies across different studies but an intermediate risk and increased frequency of the disease have been reported in recent years. The circumstances of Latin American countries are different from those of Europe and North America, both in terms of differential diagnoses and disease management. Methods: An online survey on MS was sent to 855 neurologists in nine Latin American countries. A panel of nine experts in MS analyzed the results. Results: Diagnostic and therapeutic recommendations were outlined with special emphasis on the specific needs and circumstances of Latin America. The experts proposed guidelines for MS diagnosis, treatment, and follow up, highlighting the importance of considering endemic infectious diseases in the differential diagnoses of MS, the identification of patients at high risk of developing MS in order to maximize therapeutic opportunities, early treatment initiation, and cost-effective control of treatment efficacy, as well as global assessment of disability. Conclusions: The experts recommended that healthcare systems allocate a longer consultation time for patients with MS, which must be conducted by neurologists trained in the management of the disease. All drugs currently approved must be available in all Latin American countries and must be covered by healthcare plans. The expert panel supported the creation of a permanent forum to discuss future clinical and therapeutic recommendations that may be useful in Latin American countries.

scholarly journals Adherence to Therapeutic Recommendations in Patients Suffering from Multiple Sclerosis

2020 ◽  
Vol 9 (3) ◽  
pp. 103-107
Author(s):  
Joanna Olkiewicz ◽  
◽  
Robert Bonek ◽  
Karolina Filipska ◽  
Robert Ślusarz ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Demyelinating Disease ◽  
Medical Data ◽  
Study Group ◽  
Fatigue Syndrome ◽  
Adherence Scale ◽  
The Central Nervous System ◽  
Therapeutic Recommendations ◽  
High Level

Introduction. Multiple sclerosis is a chronic, inflammatory, immune demyelinating disease of the central nervous system. The effectiveness of MS treatment depends primarily on the effectiveness of drugs and the patient’s compliance with the principles of therapy. Aim. The main aim of the study was to assess the level of adherence to therapeutic recommendations in patients with multiple sclerosis. Material and Methods. The research was carried out at the Department of Neurology and Clinical Neuroimmunology of the Regional Specialist Hospital in Grudziądz. On average 165 patients suffering from multiple sclerosis were qualified for the study. The study was conducted using the method of diagnostic survey. The variables were measured using the proprietary questionnaire containing sociodemographic and medical data and the standardized adherence scale in chronic diseases (ACDS). Results. The analysis of own research showed that patients with high-level multiple sclerosis adhere to the therapeutic recommendations (p = 0.001). The study group reported the fatigue syndrome at all ACDS levels (p = 0.002). There was no relationship between the occurrence of adverse effects of pharmacotherapy and the level of compliance with therapeutic recommendations (p > 0.05). Conclusions. It was found that the level of adherence to therapeutic recommendations in patients suffering from multiple sclerosis in the study group remained at a high level. (JNNN 2020;9(3):103–107) Key Words: adherence, multiple sclerosis, therapeutic recommendations

Microglia-derived macrophages in early multiple sclerosis plaques

1996 ◽  
Vol 22 (3) ◽  
pp. 207-215 ◽  
Author(s):  
H. Li ◽  
M. L. Cuzner ◽  
J. Newcombe
Keyword(s):  
Multiple Sclerosis
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