scholarly journals Orlans HO, Hornby SJ, Bowler IC (2011) In vitro antibiotic susceptibility patterns of bacterial keratitis isolates in Oxford, UK: a 10-year review. Eye Jan 21 [Epub ahead of print] PMID 21252952

2011 ◽  
Vol 249 (6) ◽  
pp. 797-799 ◽  
Author(s):  
Stephen Kaye ◽  
Rose Gilbert ◽  
Henri Sueke ◽  
Timothy Neal
Keyword(s):  
Antibiotic Susceptibility ◽  
Bacterial Keratitis ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns

scholarly journals Pediatric fever in neutropenia with bacteremia—Pathogen distribution and in vitro antibiotic susceptibility patterns over time in a retrospective single-center cohort study

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246654
Author(s):  
Melina Stergiotis ◽  
Roland A. Ammann ◽  
Sara Droz ◽  
Christa Koenig ◽  
Philipp Kwame Abayie Agyeman
Keyword(s):  
Antimicrobial Activity ◽  
Cancer Patients ◽  
Pediatric Cancer ◽  
Antibiotic Susceptibility ◽  
Single Center ◽  
Pediatric Cancer Patients ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns ◽  
Over Time

Background Fever in neutropenia (FN) is a potentially life-threatening complication of chemotherapy in pediatric cancer patients. The current standard of care at most institutions is emergency hospitalization and empirical initiation of broad-spectrum antibiotic therapy. Methods We analyzed in retrospect FN episodes with bacteremia in pediatric cancer patients in a single center cohort from 1993 to 2012. We assessed the distribution of pathogens, the in vitro antibiotic susceptibility patterns, and their trends over time. Results From a total of 703 FN episodes reported, we assessed 134 FN episodes with bacteremia with 195 pathogens isolated in 102 patients. Gram-positive pathogens (124, 64%) were more common than Gram-negative (71, 36%). This proportion did not change over time (p = 0.26). Coagulase-negative staphylococci (64, 32%), viridans group streptococci (42, 22%), Escherichia coli (33, 17%), Klebsiella spp. (10, 5%) and Pseudomonas aeruginosa (nine, 5%) were the most common pathogens. Comparing the in vitro antibiotic susceptibility patterns, the antimicrobial activity of ceftriaxone plus amikacin (64%; 95%CI: 56%-72%), cefepime (64%; 95%CI 56%-72%), meropenem (64%; 95%CI 56%-72), and piperacillin/tazobactam (62%; 95%CI 54%-70%), respectively, did not differ significantly. The addition of vancomycin to those regimens would have increased significantly in vitro activity to 99% for ceftriaxone plus amikacin, cefepime, meropenem, and 96% for piperacillin/tazobactam (p < 0.001). Conclusions Over two decades, we detected a relative stable pathogen distribution and found no relevant trend in the antibiotic susceptibility patterns. Different recommended antibiotic regimens showed comparable in vitro antimicrobial activity.

scholarly journals The In Vitro Antibiotic Susceptibility of Malaysian Isolates ofBurkholderia pseudomallei

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Norazah Ahmad ◽  
Rohaidah Hashim ◽  
Azura Mohd Noor
Keyword(s):  
Antibiotic Susceptibility ◽  
Burkholderia Pseudomallei ◽  
Inhibitory Concentration ◽  
Test Method ◽  
Amoxicillin Clavulanic Acid ◽  
Antibiotic Susceptibility Patterns ◽  
Potential Alternative ◽  
Ciprofloxacin Resistance ◽  
Susceptibility Patterns

Acute melioidosis may present as localised or septicaemic infections and can be fatal if left untreated.Burkholderia pseudomalleiresistant to antibiotics used for the treatment of melioidosis had been reported. The aim of this study was to determine the in vitro antibiotic susceptibility patterns ofBurkholderia pseudomalleiisolated in Malaysia to a panel of antibiotics used for the treatment of melioidosis and also to potential alternative antibiotics such as tigecycline, ampicillin/sulbactam, and piperacillin/tazobactam. A total of 170Burkholderia pseudomalleiisolates were subjected to minimum inhibitory concentration determination usingE-test method to eleven antibiotics. All isolates were sensitive to meropenem and piperacillin/tazobactam. For ceftazidime, imipenem, amoxicillin/clavulanic acid, and doxycycline resistance was observed in 1 isolate (0.6%) for each of the antibiotics. Trimethoprim/sulfamethoxazole resistance was observed in 17 (10%) isolates. For other antibiotics, ampicillin/sulbactam, chloramphenicol, tigecycline, and ciprofloxacin resistance were observed in 1 (0.6%), 6 (3.5%), 60 (35.3%) and 98 (57.7%) isolates respectively. One isolate B170/06 exhibited resistance to 4 antibiotics, namely, ciprofloxacin, chloramphenicol, trimethoprim/sulfamethoxazole, and tigecycline. In conclusion, the Malaysian isolates were highly susceptible to the current antibiotics used in the treatment of melioidosis in Malaysia. Multiple resistances to the antibiotics used in the maintenance therapy are the cause for a concern.

In vitro Antibiotic Susceptibility Patterns of Ornithobacterium rhinotracheale from Commercial Chickens in Argentina#

2016 ◽  
Vol 15 (8) ◽  
pp. 293-296
Author(s):  
Carlos D. Gornatti Churria ◽  
Panayiotis Loukopoulo ◽  
German B. Vigo ◽  
Pablo Sansalone ◽  
Mariana A. Machuca ◽  
...  
Keyword(s):  
Antibiotic Susceptibility ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns ◽  
Ornithobacterium Rhinotracheale ◽  
Commercial Chickens

Antibiotic susceptibility patterns and clones of Pseudomonas aeruginosa in Swedish ICUs

2008 ◽  
Vol 40 (6-7) ◽  
pp. 487-494 ◽  
Author(s):  
Marcus Erlandsson ◽  
Hans Gill ◽  
David Nordlinder ◽  
Christian G. Giske ◽  
Daniel Jonas ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Susceptibility ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns

scholarly journals Prevalence and antibiotic susceptibility patterns of bacteria causing urinary tract infections in Youssef Hospital Center: first report from Akkar governorate, North of Lebanon

10.3823/0802 ◽  
2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Monzer Hamze ◽  
Marwan Osman ◽  
Hassan Mallat ◽  
Elie Bou Raad
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Antibiotic Susceptibility ◽  
Susceptibility Testing ◽  
Published Data ◽  
Resistance Level ◽  
Antibiotic Susceptibility Patterns ◽  
Tract Infections ◽  
Susceptibility Patterns ◽  
Hospital Center

Background. Urinary tract infection (UTI) is common infection feature worldwide.   Infected patients are usually treated empirically treated without culture or antibiotics susceptibility testing, and which may lead to increase antibiotic resistance level. This study aims to determine the prevalence and antibiotic susceptibility patterns of common uropathogenic bacteria isolated at Youssef Hospital Center, Akkar governorate, North of Lebanon. Methods. Spot midstream of urine samples from 9662 patients with UTI symptoms who came for medical investigation to Youssef Hospital Center located in Akkar governorate.  Urine specimens were collected in sterile plastic bottles. Culture, identification and antibiotic susceptibility testing were performed using conventional tools according to the recommendations of the European Committee on Antimicrobial Susceptibility Testing. Results.  A total of 1009 bacterial uropathogens were isolated. Escherichia coli was most presented (72.5%) of all isolates, followed by Klebsiella pneumoniae (8.2%), Enterococcus spp. (5.5%), Pseudomonas aeruginosa (4.5%), Proteus spp. (3%), Enterobacter spp. (2%), Staphylococcus aureus (2%), Streptococcus agalactiae (1.6%), Staphylococcus saprophyticus (0.4%), Acinetobacter baumannii(0.2%) and Providencia rettgeri (0.1%). Moreover, the mean antibiotic resistance rates of isolates was relatively high, but comparable to previously published data in Lebanon. Conclusion. To the best of our knowledge, this is the first investigation reporting epidemiological data regarding the prevalence and antibiotic susceptibility patterns of bacterial uropathogens isolated from patients in the Akkar governorate. Our data indicated the urgent need of a strategic plan to tackle antibiotic resistance, particularly in deprived regions with poor healthcare centers.   Keywords: Uropathogens, Epidemiology, Antibiotic susceptibility, Risk factors, Akkargovernorate, North Lebanon.

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