scholarly journals Antibiotic susceptibility patterns of bacteria isolates from post-operative wound infections among patients attending Mama Lucy Kibaki Hospital, Kenya

2020 ◽  
Vol 14 (8) ◽  
pp. 420-425
Author(s):  
Amulioto Johnstone ◽  
W. Muturi Margaret ◽  
Mathenge Scholastica ◽  
M. Mutua Gideon
2019 ◽  
Author(s):  
Johnstone Amulioto ◽  
Margaret W. Muturi ◽  
Scholastica Mathenge ◽  
Gideon M. Mutua

Abstract Background Surgical site infections accounts for high mortality rates, morbidity and elevated costs of treatment for surgical patients. In recent years, surgical site infections attributed to antibiotic resistant bacteria has been on the rise globally. To effectively formulate a comprehensive treatment protocol for surgical site infection, there is need for knowing the likely causative agents and their antibiograms. In this regard, this study sought to determine the prevalence and antibiotic susceptibility patterns of bacteria isolates from post-operative wound infections among patients attending Mama Lucy Kibaki Hospital.Methods A cross-sectional descriptive study was carried out between October 2018 and March 2019. The study included patients of all age group with surgical site infections following general, obstetrics and gynecological surgeries. Pus swabs were aseptically obtained from 58 consented patients with clinical evidence of surgical site infections. Gram stain, culture, biochemical tests and antibiotic susceptibility tests were done for each pus swab. Antibiotic susceptibility testing was done using Kirby bauer disc diffusion method. Data was analysed using a statistical package for the social sciences (SPSS) version 20.Results An isolation rate of 94.8% was observed. Staphylococcus aureus 28.2% was the preponderant isolate followed by Escherichia coli 15.4% with Methicillin resistant Staphylococcus aureus accounting for 65.4% (n=17) of the total Staphylococcus species . Chloramphenicol was the most sensitive drug to all the bacteria isolates. Ampicillin and Amoxycillin recorded resistance rates >90% against positive and gram negative bacteria respectively. Klebsiella pneumoniae 81.3% and E.coli 74% were the most resistant bacteria.Conclusion Majority of the drugs were resistant to gram negative rods, therefore there is need for continuous monitoring to determine the susceptibility patterns of the most common surgical site infections bacteria isolates which are found in the hospitals.


2008 ◽  
Vol 40 (6-7) ◽  
pp. 487-494 ◽  
Author(s):  
Marcus Erlandsson ◽  
Hans Gill ◽  
David Nordlinder ◽  
Christian G. Giske ◽  
Daniel Jonas ◽  
...  

Author(s):  
Monzer Hamze ◽  
Marwan Osman ◽  
Hassan Mallat ◽  
Elie Bou Raad

Background. Urinary tract infection (UTI) is common infection feature worldwide.   Infected patients are usually treated empirically treated without culture or antibiotics susceptibility testing, and which may lead to increase antibiotic resistance level. This study aims to determine the prevalence and antibiotic susceptibility patterns of common uropathogenic bacteria isolated at Youssef Hospital Center, Akkar governorate, North of Lebanon. Methods. Spot midstream of urine samples from 9662 patients with UTI symptoms who came for medical investigation to Youssef Hospital Center located in Akkar governorate.  Urine specimens were collected in sterile plastic bottles. Culture, identification and antibiotic susceptibility testing were performed using conventional tools according to the recommendations of the European Committee on Antimicrobial Susceptibility Testing. Results.  A total of 1009 bacterial uropathogens were isolated. Escherichia coli was most presented (72.5%) of all isolates, followed by Klebsiella pneumoniae (8.2%), Enterococcus spp. (5.5%), Pseudomonas aeruginosa (4.5%), Proteus spp. (3%), Enterobacter spp. (2%), Staphylococcus aureus (2%), Streptococcus agalactiae (1.6%), Staphylococcus saprophyticus (0.4%), Acinetobacter baumannii(0.2%) and Providencia rettgeri (0.1%). Moreover, the mean antibiotic resistance rates of isolates was relatively high, but comparable to previously published data in Lebanon. Conclusion. To the best of our knowledge, this is the first investigation reporting epidemiological data regarding the prevalence and antibiotic susceptibility patterns of bacterial uropathogens isolated from patients in the Akkar governorate. Our data indicated the urgent need of a strategic plan to tackle antibiotic resistance, particularly in deprived regions with poor healthcare centers.   Keywords: Uropathogens, Epidemiology, Antibiotic susceptibility, Risk factors, Akkargovernorate, North Lebanon.


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