scholarly journals A cross-sectional study among Polish hunters: seroprevalence of hepatitis E and the analysis of factors contributing to HEV infections

2017 ◽  
Vol 206 (5) ◽  
pp. 367-378 ◽  
Author(s):  
Anna Baumann-Popczyk ◽  
Bartłomiej Popczyk ◽  
Elżbieta Gołąb ◽  
Wioletta Rożej-Bielicka ◽  
Małgorzata Sadkowska-Todys
2021 ◽  
Author(s):  
Chioma Ngozichukwu Pauline Mbachu ◽  
Joy Chinelo Ebenebe ◽  
Henry Chima Okpara ◽  
John Onuora Chukwuka ◽  
Ikechukwu Innocent Mbachu ◽  
...  

Abstract Background: There is a paucity of data on the knowledge and practice of preventive measures for Hepatitis E infection. Determination of knowledge and practice of preventive measures are necessary for informed health education for the prevention of Hepatitis E infection and other communicable diseases. The study evaluated the prevalence of Hepatitis E, knowledge, and practice of preventive measures for Hepatitis E virus infection among adolescents in rural Nigeria.Methods: This cross-sectional study was conducted over 3 months among rural Nigerian secondary school adolescents. An interviewer-based questionnaire was used to collect data on sociodemographic profile, knowledge, and practice of preventive measures for Hepatitis E infection. Blood samples collected from participants were analysed for Hepatitis E IgG using Elisa Kits (Sigma Diagnostics, USA). Data were analysed using SPSS software version 20.0. Tests of association were done with a level of significance set at 5%. Results: A total of 9 out of the 414 participants tested positive for Hepatitis E IgG antibodies giving a prevalence of 2.2%. Significant factors for Hepatitis E infection were male gender {P =0.004} and school {P < 0.001}. Most participants (98.6%) had poor knowledge of Hepatitis E infection, 239(57.7%) had good preventive practices, while 175(42.3%) had average preventive practices. Conclusion: Male gender, school, and practice of preventive measures had a significant association with Hepatitis E infection.


2013 ◽  
Vol 10 (8) ◽  
pp. 698-704 ◽  
Author(s):  
Soawapak Hinjoy ◽  
Kenrad E. Nelson ◽  
Robert V. Gibbons ◽  
Richard G. Jarman ◽  
Piyawan Chinnawirotpisan ◽  
...  

2021 ◽  
Author(s):  
H. Yasemin Balaban ◽  
Abdullah Tarık Aslan ◽  
Fatma Nur Akdoğan Kittana ◽  
Alpaslan Alp ◽  
Osman Dağ ◽  
...  

AbstractBackgroundThe renal transplant recipients (RT), allogeneic hematopoietic stem cell transplant recipients (allo-HSCT), patients with acute hepatitis (AH), and chronic hepatitis C patients (CHC) are at risk of hepatitis E virus (HEV) infection. However, seroepidemiology, risk factors to HEV exposure, and the prevalence of HEV viremia has not yet been investigated among these patients in Turkey.Materials&MethodsIn this cross-sectional study, 292 consecutive serum samples were tested for HEV immunoglobulin IgG/IgM and HEV RNA using commercial ELISA and in-house nested PCR with Sanger sequencing, respectively. Sociodemographic, clinical, laboratory data, and risk factors were collected using a questionnaire and hospital database. Multiple logistic regression analysis was employed to identify independent predictors for anti-HEV seropositivity.ResultsAmong all patients (n=292) tested for HEV RNA reactivity, only 2 patients (one RT recipient and one patient with AH) were identified as having HEV3 viremia. HEV viremia rate was 0.6% in whole group. These patients had shown no signs of chronic HEV infection for 6 months and was found to spontaneously seroconverted 6 months after enrollment. Anti-HEV IgG was positive in 29 patients yielding an HEV seroprevalence of 9.9%. Older age (aOR:1.03, 95% CI, 1.00-1.06; p:0.022) and eating undercooked meat (aOR:3.11, 95% CI, 1.08-8.92; p:0.034) were independent risk factors to anti-HEV seropositivity in all patients. Similarly, multiple logistic regression analysis demonstrated that age (aOR:1.03, 95% CI, 0.99-1.07, p:0.058) and eating undercooked meat (aOR:5.77, 95% CI, 1.49-22.25, p:0.011) were independent risk factors for anti-HEV IgG positivity in the non-immunosuppressive subgroup consisting of AH and CHC patients.ConclusionThe HEV seroprevalence rate was high (9.9%), despite low viremia rate (0.6%) in high-risk patients. The emergence of HEV3 might indicate a serious problem for these patients. Future investigations are needed to elucidate foodborne transmission routes of HEV in Turkey.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chioma Ngozichukwu Pauline Mbachu ◽  
Joy Chinelo Ebenebe ◽  
Henry Chima Okpara ◽  
John Onuora Chukwuka ◽  
Ikechukwu Innocent Mbachu ◽  
...  

Abstract Background Currently, there is a paucity of data on the knowledge and practice of preventive measures for Hepatitis E infection in Nigerian populations. This study provided data on the prevalence, knowledge and practices of prevention in an adolescent population from Nigeria. Methods This cross-sectional study was conducted over 3 months among rural Nigerian secondary school adolescents. An interviewer-based questionnaire was used to collect data on sociodemographic profile, knowledge, and practice of preventive measures for Hepatitis E infection. Blood samples collected from participants were analysed for Hepatitis E IgG using Elisa Kits (Sigma Diagnostics, USA). Data were analysed using SPSS software version 20.0. Tests of association were done with a level of significance set at 5%. Results A total of 9 out of the 414 participants tested positive for Hepatitis E IgG antibodies giving a prevalence of 2.2%. Significant factors for Hepatitis E infection were male gender {P = 0.004} and school {P < 0.001, however logistic regression gave infinite value. Most participants (98.6%) had poor knowledge of Hepatitis E infection, 239(57.7%) had good preventive practices, while 175(42.3%) had average preventive practices. Conclusion A low prevalence of HEV infection was recorded among study participants. There was poor knowledge of Hepatitis E, and association could not be established between HEV infection and individual preventive practices.


PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e87669 ◽  
Author(s):  
Heimo Lagler ◽  
Wolfgang Poeppl ◽  
Heidi Winkler ◽  
Harald Herkner ◽  
Angelus Faas ◽  
...  

2021 ◽  
Vol 15 (5) ◽  
pp. 1341-1343
Author(s):  
S. Hafeez ◽  
Z. Hafeez ◽  
Sana Hafeez ◽  
S. Riaz ◽  
R. R. Khan ◽  
...  

Objective: To identify the maternofetal outcomes of Acute Hepatitis E in Pregnancy Methods: A cross-sectional study was conducted at the Obstetrics and Gynecology Department of Services Institute of Medical Sciences, Lahore. It included 41 women with gestational age >32 weeks, singleton pregnancy, presenting with Hepatitis E infection. Their demographic and pregnancy-related characteristics were included. Maternal and fetal outcomes were assessed. Data was entered and analyzed using SPSS v.25. Results: Mean age of the participatns was 27.12 ± 3.85 years; the mean gestational age was 31.00 ± 6.15 weeks. Thirty one patients (75.6%) were admitted through the emergency. Twenty four (58.5%) needed packed cell transfusion and 32 (78%) needed fresh frozen plasma transfusion. Eleven patients (26.8%) developed hepatic encephalopathy and all of them required intensive care admission. The maternal mortality rate was 4 (9.8%). Thirty eight (92.1%) pregnancies were viable at the time of arrival. The fetal mortality rate was 7 (17.1%). Conclusion: HEV infections significantly contribute to materno-fetal morbidity and mortality. Screening for and monitoring HEV infection earlier during the pregnancy should be of primary public health importance. Improving awareness in women of childbearing age regarding HEV transmission and its adverse fetal effects should be prioritized. Key words: Hepatitis E virus, Maternofetal Outcomes, pregnancy, Childbearing age


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