A Cross-Sectional Study of Hepatitis E Virus Infection in Pigs in Different-Sized Farms in Northern Thailand

2013 ◽  
Vol 10 (8) ◽  
pp. 698-704 ◽  
Author(s):  
Soawapak Hinjoy ◽  
Kenrad E. Nelson ◽  
Robert V. Gibbons ◽  
Richard G. Jarman ◽  
Piyawan Chinnawirotpisan ◽  
...  
Keyword(s):  
Virus Infection ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Northern Thailand

scholarly journals Hepatitis E virus seroprevalence and associated risk factors in high-risk groups: A cross-sectional study from Turkey

2021 ◽  
Author(s):  
H. Yasemin Balaban ◽  
Abdullah Tarık Aslan ◽  
Fatma Nur Akdoğan Kittana ◽  
Alpaslan Alp ◽  
Osman Dağ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis E Virus ◽  
Multiple Logistic Regression Analysis ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Transplant Recipients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Independent Risk Factors ◽  
Undercooked Meat

AbstractBackgroundThe renal transplant recipients (RT), allogeneic hematopoietic stem cell transplant recipients (allo-HSCT), patients with acute hepatitis (AH), and chronic hepatitis C patients (CHC) are at risk of hepatitis E virus (HEV) infection. However, seroepidemiology, risk factors to HEV exposure, and the prevalence of HEV viremia has not yet been investigated among these patients in Turkey.Materials&MethodsIn this cross-sectional study, 292 consecutive serum samples were tested for HEV immunoglobulin IgG/IgM and HEV RNA using commercial ELISA and in-house nested PCR with Sanger sequencing, respectively. Sociodemographic, clinical, laboratory data, and risk factors were collected using a questionnaire and hospital database. Multiple logistic regression analysis was employed to identify independent predictors for anti-HEV seropositivity.ResultsAmong all patients (n=292) tested for HEV RNA reactivity, only 2 patients (one RT recipient and one patient with AH) were identified as having HEV3 viremia. HEV viremia rate was 0.6% in whole group. These patients had shown no signs of chronic HEV infection for 6 months and was found to spontaneously seroconverted 6 months after enrollment. Anti-HEV IgG was positive in 29 patients yielding an HEV seroprevalence of 9.9%. Older age (aOR:1.03, 95% CI, 1.00-1.06; p:0.022) and eating undercooked meat (aOR:3.11, 95% CI, 1.08-8.92; p:0.034) were independent risk factors to anti-HEV seropositivity in all patients. Similarly, multiple logistic regression analysis demonstrated that age (aOR:1.03, 95% CI, 0.99-1.07, p:0.058) and eating undercooked meat (aOR:5.77, 95% CI, 1.49-22.25, p:0.011) were independent risk factors for anti-HEV IgG positivity in the non-immunosuppressive subgroup consisting of AH and CHC patients.ConclusionThe HEV seroprevalence rate was high (9.9%), despite low viremia rate (0.6%) in high-risk patients. The emergence of HEV3 might indicate a serious problem for these patients. Future investigations are needed to elucidate foodborne transmission routes of HEV in Turkey.

scholarly journals Hepatitis E Virus Seroprevalence in Austrian Adults: A Nationwide Cross-Sectional Study among Civilians and Military Professionals

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e87669 ◽  
Author(s):  
Heimo Lagler ◽  
Wolfgang Poeppl ◽  
Heidi Winkler ◽  
Harald Herkner ◽  
Angelus Faas ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Seroprevalence and risk assessment of viral hepatitis E infection in a group of exposed persons from Republic of Moldova

2019 ◽  
Vol 13 (05) ◽  
pp. 461-464
Author(s):  
Octavian Sajin ◽  
Constantin Spînu ◽  
Iurie Pînzaru ◽  
Maria Isac ◽  
Igor Spînu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Occupational Exposure ◽  
Viral Hepatitis ◽  
Textile Industry ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Occupationally Exposed

Introduction: Viral hepatitis E is considered to be an important issue for public health in developing countries. The aim of the present study is to evaluate morbidity and risk factors in occupationally exposed groups such as people working on sausage production. Methodology: Seroprevalence of HEV (hepatitis E virus) and risk factors to infection were determined in a cross-sectional study of two groups of populations: people working on sausage production (n = 70) and persons without occupational exposure (people working in the textile industry n = 70) in Moldova, a country without reported cases of hepatitis E. Results: The seroprevalence of HEV was 14.3% (CI 95%, 13.1-15.5%) in the group of exposed, compared with no cases in the non-exposed group that indicates on no previous infectious contact with hepatitis E virus. Conclusions: The increased seroprevalence of HEV among persons with occupational exposure to swine meat suggest animal-to-human transmission of this infection.

scholarly journals Seroprevalence of hepatitis E virus in risk populations and blood donors in a referral hospital in the south of Brazil

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marisa Boff Costa ◽  
Michele Soares Gomes Gouvêa ◽  
Samira Chuffi ◽  
Gustavo Hirata Dellavia ◽  
Felipe Ornel ◽  
...  
Keyword(s):  
Low Income ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Total Sample ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Elisa Test ◽  
Confirmatory Test ◽  
Cross Sectional ◽  
Populations At Risk

AbstractThe prevalence of anti-hepatitis E virus (HEV) antibodies has a high heterogeneity worldwide. South American data are still scarce. The aim of this study was to evaluate the prevalence of HEV in populations at risk in comparison to blood donors (BD). A cross-sectional study was carried out in adults of different risk populations including crack users (CK), residents in a low income area (LIA), cirrhotic (CIR) and liver transplant patients (LT) compared with BD. The WANTAI HEV ELISA test was used and real-time PCR (in-house for screening and ALTONA as confirmatory test) for HEV RNA screening. A total of 400 participants were included. Anti-HEV IgG was positive in 19.5% of the total sample, reaching the highest rate in the CIR group, 22.5%, followed by CK, LT, and LIA (20%, 18.7%, and 17.5%, respectively). The prevalence found in BD individuals was of 18.7% (p = NS). Anti-HEV IgM was positive in only 1.5% of the sample (6/400). No blood or stools samples were positive for HEV RNA. The seroprevalence reported is among the highest rates ever found in Brazil. Considering the intense diagnostic investigation, data show that HEV circulation is more common that might be expected in our country.

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