Comparison of two new techniques for the management of malignant central airway obstruction: argon plasma coagulation with mechanical tumor resection versus cryorecanalization

2017 ◽  
Vol 32 (4) ◽  
pp. 1879-1884 ◽  
Author(s):  
Derya Kızılgöz ◽  
Zafer Aktaş ◽  
Aydın Yılmaz ◽  
Ayperi Öztürk ◽  
Fatih Seğmen
Plasma ◽  
2018 ◽  
Vol 1 (1) ◽  
pp. 189-200 ◽  
Author(s):  
Lawan Ly ◽  
Sterlyn Jones ◽  
Alexey Shashurin ◽  
Taisen Zhuang ◽  
Warren Rowe ◽  
...  

The use of plasma energy has expanded in surgery and medicine. Tumor resection in surgery and endoscopy has incorporated the use of a plasma scalpel or catheter for over four decades. A new plasma energy has expanded the tools in surgery: Cold Atmospheric Plasma (CAP). A cold plasma generator and handpiece are required to deliver the CAP energy. The authors evaluated a new Cold Plasma Jet System. The Cold Plasma Jet System consists of a USMI Cold Plasma Conversion Unit, Canady Helios Cold Plasma® Scalpel, and the Canady Plasma® Scalpel in Hybrid and Argon Plasma Coagulation (APC) modes. This plasma surgical system is designed to remove the target tumor with minimal blood loss and subsequently spray the local area with cold plasma. In this study, various operational parameters of the Canady Plasma® Scalpels were tested on ex vivo normal porcine liver tissue. These conditions included various gas flow rates (1.0, 3.0, 5.0 L/min), powers (20, 40, 60 P), and treatment durations (30, 60, 90, 120 s) with argon and helium gases. Plasma length, tissue temperature changes, and depth and eschar injury magnitude measurements resulting from treatment were taken into consideration in the comparison of the scalpels. The authors report that a new cold plasma jet technology does not produce any thermal damage to normal tissue.


PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e8687
Author(s):  
Xiaoke Chen ◽  
Yiping Zhou ◽  
Haiqiong Yu ◽  
Yue Peng ◽  
Liping Xia ◽  
...  

Background Interventional bronchoscopy for hypoxemic patients with central airway obstruction (CAO) is typically performed under general anesthesia. This approach poses remarkable challenge for both bronchoscopist and anesthesiologist. Noninvasive ventilation (NIV) during flexible bronchoscopy (FB) has been successfully used in hypoxemic patients, but rarely in the treatment of hypoxemic patients with CAO. Objective To evaluate the feasibility of therapeutic FB assisted with NIV for therapy of hypoxemic patients with CAO. Method Twenty-nine hypoxemic CAO patients treated with FB from December 2010 to May 2016 in our hospital were retrospectively reviewed, either aided with NIV under sedation (NIV group ) or through artificial airway under general anesthesia (control group). Interventional procedures included balloon dilation, electrocautery and argon plasma coagulation Result Fifteen patients were enrolled in the NIV group and 14 in the control group. The success rate (93.3% VS 92.9%, p = 1.0), procedure time (60.5 ± 4.2 min VS 67.8 ± 5.6 min, p = 0.31) and oxygenation improvement between the two groups have no significant difference. Less reduction of systolic blood pressure and heart rate during procedure was observed in the NIV group. The NIV group showed shorter admission time before procedure than the control group (35.1 ± 4.6 h VS 55.6 ± 5.6 h, p < 0.01). In addition, procedure fee in the NIV group was significantly less than that in the control group (540.7 ± 62.8$ VS975.4 ± 69.5$, p < 0.0001). Conclusion FB assisted with NIV is a safe, efficient and economic method for therapy of selected hypoxemic patients with CAO.


CHEST Journal ◽  
2019 ◽  
Vol 156 (4) ◽  
pp. A202-A203
Author(s):  
Daniel Ospina-Delgado ◽  
Fayez Kheir ◽  
Barbara Vidal ◽  
Jason Beattie ◽  
Paul VanderLaan ◽  
...  

CHEST Journal ◽  
2001 ◽  
Vol 119 (3) ◽  
pp. 781-787 ◽  
Author(s):  
Rodolfo C. Morice ◽  
Turhan Ece ◽  
Ferah Ece ◽  
Leendert Keus

2021 ◽  
Vol 29 (3) ◽  
pp. 360-369
Author(s):  
Efsun Gonca Uğur Chousein ◽  
Demet Turan ◽  
Mehmet Akif Özgül ◽  
Erdoğan Çetinkaya

Background: In this study, we aimed to share our singlecenter experience and to investigate the effect of interventional bronchoscopic procedures on secondary pulmonary malignancies in terms of complications, success, and survival rates. Methods: A total of 83 patients (42 males, 41 females; mean age: 57.8±15.2 years; range, 18 to 94 years) with secondary pulmonary malignancies who underwent interventional bronchoscopic procedures between January 2009 and December 2019 were retrospectively reviewed. Data including demographic and clinical characteristics of the patients, complications, and success and survival rates were recorded. Results: The most common secondary pulmonary malignancies were kidney and thyroid tumors with the complaints of cough, shortness of breath, and hemoptysis. The mean duration before the diagnosis was 34.7±52.8 (range, 0.1 to 219.3) months, and the mean survival after the diagnosis were 10±13.1 (range, 0.2 to 44.4) months. A total of 92% of the patients had an airway obstruction of >50% and the interventional bronchoscopic procedures such as argon plasma coagulation, laser, cryo, and mechanical resection were successful in achieving airway patency. Laser application was found to significantly improve survival (p=0.015). Acute complication rate was 8.4% and mortality rate was 0%. Conclusion: In patients with tracheobronchial lesions due to secondary pulmonary malignancies, interventional bronchoscopic procedures, regardless of the stage of the disease, provide rapid palliation in life-threatening symptoms such as dyspnea and hemoptysis due to airway obstruction, prolonging patient"s survival and gain time for additional treatments to take effect for primary disease.


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