Predictors of renal scar in children with urinary infection and vesicoureteral reflux

2008 ◽  
Vol 23 (12) ◽  
pp. 2227-2232 ◽  
Author(s):  
Alper Soylu ◽  
Belde Kasap Demir ◽  
Mehmet Türkmen ◽  
Özlem Bekem ◽  
Murat Saygı ◽  
...  
2004 ◽  
Vol 57 (3-4) ◽  
pp. 159-163 ◽  
Author(s):  
Jan Varga ◽  
Dragana Zivkovic ◽  
Dusanka Dobanovacki ◽  
Slobodan Petrovic

Introduction Vesicoureteral reflux, urinary infection and pyelonephritic scarring represent a well known triad in pediatric practice that may lead to severe scarring of kidneys, and development of so called reflux nephropathy. Apart from standard therapeutic options (conservative treatment and surgical therapy), endoscopic correction of refluxing vesicoureteral junction has been introduced into clinical practice. Material and methods This study included endoscopically treated patients with primary vesicoureteral reflux over a 9-year period, as well as certain clinical parameters. Results Endoscopic correction of primary vesicoureteral reflux with teflon paste has been successful in up to 93.5% of patients. After one application vesicoureteral reflux disappeared in 58.8% of cases. After two applications 86.0% of ureters were cured, whereas the third application had no further effect on existing reflux. Improvement with spontaneous regression of reflux was established in 7.5% of treated ureters. Discussion Endoscopic correction should be performed in all patients with third grade vesicoureteral reflux, and in selected patients with second and fourth grade reflux. First grade reflux should be treated conservatively, and fifth grade reflux should be treated surgically. Conclusion Endoscopic treatment of primary vesicoureteral reflux is an easy, simple, fast and safe procedure that prevents regurgitation of urine from bladder to upper parts of the urinary system in most of cases.


1972 ◽  
Vol 107 (5) ◽  
pp. 755-757 ◽  
Author(s):  
Daniel Lenaohan ◽  
Alexander S. Cass ◽  
Leo J. Cussen ◽  
F. Douglas Stephens

2018 ◽  
Vol 29 (05) ◽  
pp. 470-474
Author(s):  
Bilge Karabulut ◽  
Gulsah Bayram ◽  
Can Ihsan Oztorun ◽  
Burak Ozcift ◽  
Tuğrul Hüseyin Tiryaki

Introduction Detecting renal scar is important in pediatric patients with vesicoureteral reflux (VUR) for deciding on treatment option. The aim of this study is to detect whether freehand elastosonography technique could be an alternative to dimercaptosuccinic acid (DMSA) scan in determining renal scar formation. Materials and Methods Between November 2015 and April 2016, 25 VUR patients, age ranging from 3 to 17 years admitted to our clinic, had urinary ultrasound and elastosonography, and data of approximately 147 renal region were recorded. Data were upper, middle, and lower pole renal parenchymal thickness and echogenicities obtained by ultrasound and these poles strain target (ST), strain reference (SR), and strain index (SI) values obtained by freehand elastosonography. DMSA scan data (differential function and upper, middle, and lower pole parenchymal scar formation) were recorded. Results Scar formation and more than 10% reduction in differential function in renal scan were statistically higher in renal regions in which parenchymal thinning and echogenicity increase was detected by ultrasound. There was no elastosonographic data difference between renal units with and without differential function decrease. Also, there was no elastosonographic data difference between renal units with and without scar formation. Conclusion In this study, we could not find any significant difference in term of tissue tension values (ST and SI) measured by freehand elastosonography between renal units with and without scar formation in renal scan.


PEDIATRICS ◽  
1972 ◽  
Vol 50 (4) ◽  
pp. 661-662
Author(s):  
Alan D. Perlmutter ◽  
Joseph Y. Dwoskin

Blank and Girdany's attempt to disprove a relationship between pyelonephritis and vesicoureteral reflux is at variance with other published reports. We followed 281 children with vesicoureteral refiux and a history of urinary infection at Boston Children's Hospital Medical Center. Using accepted radiographic criteria, 35% initially had some evidence of unilateral or bilateral pyelonephnitis, a prevalence similarly reported by MacGregor et al. The positive relationship noted between grades of reflux severity and the proportion of children having pyelonephritic changes was also noted by Rolleston et al. In our series, 80% had reflux of moderate or lesser degree; a minority thus fell into categories of more severe reflux and more prevalent renal damage.


2020 ◽  
Author(s):  
YAN LIU ◽  
HONG WEN WANG ◽  
JING CHEN ◽  
DONG LIU ◽  
Quan Chun Cai

Abstract Background Acute focal bacterial nephritis (AFBN) is a seldom infection in children kidney disease,Vesicoureteral reflux(VUR) often exist in infants who are easy to have urinary tract infection(UTI).In this study,we summarize the clinical features ,imaging and therapy. Methods eleven patients with AFBN and VUR aged from two months to eight months treated at this hospital from January 2017 to August 2019 were reviewed.The manifestations,urine and blood tests, imagings,treatments of patients were analyzed retrospectively. Results Fever was the common symptom,blood CRP was higher than normal(25 mg/L-200 mg/L),The percentage of neutrophils in blood was 52%-85%.The ratio of neutrophils to lymphocytes was 1.39–11.6,Routine urine microscopic examination of leukocyte was +∽3+/HP,Urine culture samples were 42, 34 samples were positive, the positive rate was 80.95%.Diagnosis was set by CT combined MCU.Enhanced CT conducted for all patients showed hypoperfused wedged-shaped or round and space-occupying lesions in kidney.MCU conducted showed I-V grade VUR in single or both sides.9 cases were treated with prophylactic antibiotics, DxHA injection was operated on 1 case, cohen operation for another patient.Relapses were rarely occur after insisting on treatment. Conclusion AFBN in children are rare and associated with VUR. Patients with AFBN should perform MCU to find out VUR and insist on prophylactic antibiotic until the VUR disappeared, patients with recurrent infection and serious VUR need urological treatment in order to prevent the formation of renal scar.


Urology ◽  
1973 ◽  
Vol 1 (5) ◽  
pp. 439-443 ◽  
Author(s):  
Lloyd Harrison ◽  
Alexander Cass ◽  
Bill Bullock ◽  
William Boyce ◽  
Clair Cox

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