Premonitory Urge for Tics Scale (PUTS): replication and extension of psychometric properties in youth with chronic tic disorders (CTDs)

2017 ◽  
Vol 125 (4) ◽  
pp. 727-734 ◽  
Author(s):  
Jeremy M. Raines ◽  
Kimberly R. Edwards ◽  
Martin F. Sherman ◽  
Christopher I. Higginson ◽  
Joel B. Winnick ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Tic Disorders ◽  
Chronic Tic Disorders ◽  
Premonitory Urge

scholarly journals Psychometric Properties of the Chinese Version of the Premonitory Urge for Tics Scale: A Preliminary Report

2021 ◽  
Vol 12 ◽  
Author(s):  
Ying Li ◽  
Douglas W. Woods ◽  
Yi Gu ◽  
Liping Yu ◽  
Junjuan Yan ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Psychometric Properties ◽  
Preliminary Report ◽  
Pediatric Patients ◽  
Age Groups ◽  
Reliability And Validity ◽  
Chinese Version ◽  
Tic Disorders ◽  
Chinese Patients ◽  
Premonitory Urge

Premonitory urges (PUs) are sensory phenomena that immediately precede tics. The Premonitory Urge for Tics Scale (PUTS) is widely used to assess the severity of PUs, but the psychometric properties of PUTS and clinical features of PU in Chinese patients with tic disorders are still unclear. In this study, we examined the psychometric properties of the Chinese version of the PUTS in a large sample (including 367 Chinese pediatric patients with tic disorders). We found no difference in PU in different age groups. The exploratory factor analysis (EFA) of PUTS showed the emergence of four primary factors. The results of reliability and validity analyses indicated that the Chinese version showed good psychometric properties. It seemed that PU was associated with the severity of obsession symptoms in patients with tic disorders. Network analysis showed that Item 7 is a critical node for the PU, in addition to Items 1 and 4. Overall, the Chinese version of PUTS can be used in Chinese child and adolescent patients with tic disorders, particularly for patients with Tourette syndrome.

scholarly journals Validity and clinical utility of the obsessive compulsive inventory - child version: further evaluation in clinical samples

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Kristina Aspvall ◽  
Matti Cervin ◽  
Per Andrén ◽  
Sean Perrin ◽  
David Mataix-Cols ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Clinical Utility ◽  
Tic Disorders ◽  
Self Report ◽  
Clinical Samples ◽  
Older Children ◽  
Obsessive Compulsive ◽  
Swedish Version ◽  
Compulsive Disorder ◽  
Chronic Tic Disorders

Abstract Background Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder. Currently, the Obsessive Compulsive Inventory-Child Version (OCI-CV) is the only self-report measure that fully captures this symptom heterogeneity in children and adolescents. The psychometric properties of the OCI-CV are promising but evaluations in large clinical samples are few. Further, no studies have examined whether the measure is valid in both younger and older children with OCD and whether scores on the measure are elevated in youths with OCD compared to youths with other mental disorders. Methods To address these gaps in the literature, we investigated the psychometric properties and validity of a Swedish version of the OCI-CV in a large clinical sample of youth aged 6–18 years with OCD (n = 434), anxiety disorders (n = 84), and chronic tic disorders (n = 45). Results Internal consistency coefficients at the total scale and subscale level were consistent with the English original and in the acceptable range. Confirmatory factor analyses revealed an adequate fit for the original six-factor structure in both younger and older children with OCD. Correlations between total scores on the OCI-CV and the Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) were small at pre-treatment (r = 0.19) but large at post-treatment (r = 0.62). Youth with OCD scored higher than those with anxiety and chronic tic disorders, and the OCI-CV was sensitive to symptom change for youth undergoing treatment for OCD. Conclusions This Swedish version of the OCI-CV appears to be a valid and reliable measure of the OCD symptom dimensions across age groups and has good clinical utility.

scholarly journals Relationships Between Premonitory Urge and Anxiety in Youth With Chronic Tic Disorders

2014 ◽  
Vol 44 (3) ◽  
pp. 235-248 ◽  
Author(s):  
Michelle Rozenman ◽  
Olivia E. Johnson ◽  
Susanna W. Chang ◽  
Douglas W. Woods ◽  
John T. Walkup ◽  
...  
Keyword(s):  
Tic Disorders ◽  
Chronic Tic Disorders ◽  
Premonitory Urge

scholarly journals Validity and clinical utility of the Obsessive Compulsive Inventory - Child Version: Further evaluation in clinical samples

2019 ◽  
Author(s):  
Kristina Aspvall ◽  
Matti Cervin ◽  
Per Andrén ◽  
Sean Perrin ◽  
David Mataix-Cols ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Clinical Utility ◽  
Tic Disorders ◽  
Self Report ◽  
Clinical Samples ◽  
Older Children ◽  
Obsessive Compulsive ◽  
Swedish Version ◽  
Compulsive Disorder ◽  
Chronic Tic Disorders

Background: Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder. Currently, the Obsessive Compulsive Inventory-Child Version (OCI-CV) is the only self-report measure that fully captures this symptom heterogeneity in children and adolescents. The psychometric properties of the OCI-CV are promising but evaluations in large clinical samples are few. Further, no studies have examined whether the measure is valid in both younger and older children with OCD and whether scores on the measure are elevated in youths with OCD compared to youths with other mental disorders. Methods: To address these gaps in the literature, we investigated the psychometric properties and validity of a Swedish version of the OCI-CV in a large clinical sample of youth aged 6-18 years with OCD (n = 434), anxiety disorders (n = 84), and chronic tic disorders (n = 45). Results: Internal consistency coefficients at the total scale and subscale level were consistent with the English original and in the acceptable range. Confirmatory factor analyses revealed an adequate fit for the original six-factor structure in both younger and older children with OCD. Correlations between total scores on the OCI-CV and the Children’s Yale-Brown Obsessive Compulsive Scale (CY-BOCS) were small at pre-treatment (r = 0.19) but large at post-treatment (r = 0.62). Youth with OCD scored higher than those with anxiety and chronic tic disorders, and the OCI-CV was sensitive to symptom change for youth undergoing treatment for OCD. Conclusions: This Swedish version of the OCI-CV appears to be a valid and reliable measure of the OCD symptom dimensions across age groups and has good clinical utility.

Initial Psychometric Properties of a Brief Parent-Report Instrument for Assessing Tic Severity in Children with Chronic Tic Disorders

2009 ◽  
Vol 31 (3) ◽  
pp. 181-191 ◽  
Author(s):  
Susanna Chang ◽  
Michael B. Himle ◽  
Benjamin T. P. Tucker ◽  
Douglas W. Woods ◽  
John Piacentini
Keyword(s):  
Psychometric Properties ◽  
Parent Report ◽  
Tic Disorders ◽  
Tic Severity ◽  
Chronic Tic Disorders

scholarly journals Clinical Correlates of Health-Related Quality of Life in Adults With Chronic Tic Disorder

2021 ◽  
Vol 12 ◽  
Author(s):  
David A. Isaacs ◽  
Heather R. Riordan ◽  
Daniel O. Claassen
Keyword(s):  
Quality Of Life ◽  
Tic Disorders ◽  
Self Report ◽  
Obsessive Compulsive ◽  
Quality Of Life Scale ◽  
Tic Severity ◽  
Health Related ◽  
Chronic Tic Disorders ◽  
Premonitory Urge

Tics are the hallmark feature of Tourette syndrome (TS), but psychiatric and sensory symptoms are widely prevalent and increasingly recognized as core manifestations of the disorder. Accumulating evidence suggests that these psychiatric and sensory symptoms exert greater influence on quality of life (QOL) than tics themselves. However, much remains uncertain about determinants of QOL in TS due to the complexity of the clinical presentation. Here, we sought to clarify the association between health-related QOL (HRQOL) and common psychiatric and sensory symptoms in adults with TS and other chronic tic disorders. To do so, we prospectively recruited 52 patients from a tertiary care clinic to complete self-report measures assessing HRQOL (Gilles de la Tourette-Quality of Life Scale, GTS-QOL), depression (Patient Health Questionnaire-9, PHQ-9), anxiety (Generalized Anxiety Disorder Scale-7, GAD-7), obsessive-compulsive symptoms (Dimensional Obsessive-Compulsive Scale, DOCS), attention deficit hyperactivity disorder symptoms (Adult ADHD Self-Report Screening Scale for DSM-5, ASRS-V), and premonitory urge (Premonitory Urge to Tic Scale, PUTS). All participants were also administered the Yale Global Tic Severity Scale (YGTSS) to quantify tic severity. Using correlational analysis and multivariable linear regression modeling, we found that GTS-QOL score was significantly associated with scores from all other rating scales, with the exception of the PUTS. GTS-QOL was most strongly associated with PHQ-9, followed by ASRS-V, GAD-7, DOCS, and YGTSS total tic score. The regression model including these five independent variables, as well as sex, explained 79% of GTS-QOL score variance [F(6,40) = 29.6, p < 0.001]. Specific psychiatric symptoms differentially impacted physical, psychological, and cognitive HRQOL. Systematic assessment of psychiatric comorbidities is imperative for clinical care and clinical research efforts directed at improving QOL in adults with chronic tic disorders.

scholarly journals Predictors of therapeutic treatment outcome in adolescent chronic tic disorders

BJPsych Open ◽  
2019 ◽  
Vol 5 (5) ◽  
Author(s):  
J. B. Nissen ◽  
E. T. Parner ◽  
P. H. Thomsen
Keyword(s):  
Treatment Outcome ◽  
Depressive Symptoms ◽  
Functional Impairment ◽  
Therapeutic Intervention ◽  
Tic Disorders ◽  
Individual Treatment ◽  
Habit Reversal Training ◽  
Tic Severity ◽  
Chronic Tic Disorders ◽  
Premonitory Urge

Background Chronic tic disorders may have a major impact on a child's function. A significant effect has been shown for combined habit reversal training (HRT) and exposure response prevention (ERP) treatment delivered in an individual and group setting. Aims The present study examines predictors and moderators of treatment outcome after an acute therapeutic intervention. Method Fifty-nine children and adolescents were randomised to manualised treatment combining HRT and ERP as individual or group training. Age, gender, baseline tic severity, Premonitory Urge for Tics Scale (PUTS) scores, Beliefs about Tic Scale (BATS) scores, hypersensitivity and comorbid psychiatric symptoms were analysed as predictors of outcome. The same characteristics were examined as moderators for individual versus group treatment. Outcome measures included the change in total tic severity (TTS) score and functional impairment score (as measured by the Yale Global Tic Severity Scale (YGTSS)). Results Internalising symptoms predicted a lesser decrease in functional impairment. The occurrence of obsessive–compulsive symptoms predicted a larger decrease in TTS. Baseline hypersensitivity and high scores on depressive symptoms favoured individual treatment. High baseline PUTS scores favoured group therapy. Conclusions This is the first study examining factors predicting and moderating perceived functional impairment following a therapeutic intervention. The study adds to the knowledge on predictors and moderators of TTS. Furthermore, this is the first study examining the effect of the BATS score. The study points towards factors that may influence treatment outcome and that require consideration when choosing supplemental treatment. This applies to comorbid anxiety and depressive symptoms, and to the child's belief about their tics and premonitory urge. Declaration of interest None.

scholarly journals Altered urinary tetrahydroisoquinoline derivatives in patients with Tourette syndrome: reflection of dopaminergic hyperactivity?

2020 ◽  
Author(s):  
Philipp Capetian ◽  
Veit Roessner ◽  
Caroline Korte ◽  
Susanne Walitza ◽  
Franz Riederer ◽  
...  
Keyword(s):  
Tourette Syndrome ◽  
Diagnostic Value ◽  
Tic Disorders ◽  
Operating Characteristics ◽  
Roc Curve Analysis ◽  
Two Phase ◽  
Dopaminergic Neurotransmission ◽  
Hyperactivity Disorder ◽  
The Central Nervous System ◽  
Chronic Tic Disorders

AbstractTetrahydroisoquinolines (TIQs) such as salsolinol (SAL), norsalsolinol (NSAL) and their methylated derivatives N-methyl-norsalsolinol (NMNSAL) and N-methyl-salsolinol (NMSAL), modulate dopaminergic neurotransmission and metabolism in the central nervous system. Dopaminergic neurotransmission is thought to play an important role in the pathophysiology of chronic tic disorders, such as Tourette syndrome (TS). Therefore, the urinary concentrations of these TIQ derivatives were measured in patients with TS and patients with comorbid attention-deficit/hyperactivity disorder (TS + ADHD) compared with controls. Seventeen patients with TS, 12 with TS and ADHD, and 19 age-matched healthy controls with no medication took part in this study. Free levels of NSAL, NMNSAL, SAL, and NMSAL in urine were measured by a two-phase chromatographic approach. Furthermore, individual TIQ concentrations in TS patients were used in receiver-operating characteristics (ROC) curve analysis to examine the diagnostic value. NSAL concentrations were elevated significantly in TS [434.67 ± 55.4 nmol/l (standard error of mean = S.E.M.), two-way ANOVA, p < 0.0001] and TS + ADHD patients [605.18 ± 170.21 nmol/l (S.E.M.), two-way ANOVA, p < 0.0001] compared with controls [107.02 ± 33.18 nmol/l (S.E.M.), two-way ANOVA, p < 0.0001] and NSAL levels in TS + ADHD patients were elevated significantly in comparison with TS patients (two-way ANOVA, p = 0.017). NSAL demonstrated an AUC of 0.93 ± 0.046 (S.E.M) the highest diagnostic value of all metabolites for the diagnosis of TS. Our results suggest a dopaminergic hyperactivity underlying the pathophysiology of TS and ADHD. In addition, NSAL concentrations in urine may be a potential diagnostic biomarker of TS.

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