Pronounced risk of nontraumatic osteonecrosis of the femoral head among cigarette smokers who have never used oral corticosteroids: a multicenter case–control study in Japan

2012 ◽  
Vol 17 (6) ◽  
pp. 730-736 ◽  
Author(s):  
Shinji Takahashi ◽  
Wakaba Fukushima ◽  
Yoshio Hirota ◽  
Hiroaki Nakamura ◽  
Toshikazu Kubo ◽  
...  
2010 ◽  
Vol 15 (2) ◽  
pp. 185-191 ◽  
Author(s):  
Motonobu Sakaguchi ◽  
Takashi Tanaka ◽  
Wakaba Fukushima ◽  
Toshikazu Kubo ◽  
Yoshio Hirota

2013 ◽  
Vol 8 (1) ◽  
pp. 22650 ◽  
Author(s):  
Helmi Ben Saad ◽  
Mehdi Khemiss ◽  
Saida Nhari ◽  
Mejda Ben Essghaier ◽  
Sonia Rouatbi

2020 ◽  
Author(s):  
Rasmus Klose-Jensen ◽  
Andreas Wiggers Nielsen ◽  
Louise Brøndt Hartlev ◽  
Jesper Skovhus Thomasen ◽  
Lene Warner Thorup Boel ◽  
...  

Abstract Objective The objective of this cross-sectional case-control study was to determine the prevalence and size of marginal and subarticular osteophytes in patients with osteoarthritis (OA), and to compare these to that of a control group. Design We investigated femoral heads from 25 patients with OA following hip replacement surgery, and 25 femoral heads from a control group obtained post-mortem . The area and boundary length of the femoral head, marginal osteophytes, and subarticular osteophytes were determined with histomorphometry. Marginal osteophytes were defined histologically as bony projections at the peripheral margin of the femoral head, while subarticular osteophytes were defined as areas of bone that expanded from the normal curvature of the femoral head into the articular cartilage. Results The prevalence of OA patients with marginal- and subarticular osteophytes were 100% and 84%, respectively. Whereas the prevalence of the participants in the control group with marginal- and subarticular osteophytes were 56% and 28%, respectively. The area and boundary length of marginal osteophytes was (median (Interquartile range)) 165.3mm 2 (121.4 – 254.0) mm 2 and 75.1 mm (50.8 – 99.3) mm for patients with OA compared to 0 mm 2 (0 – 0.5) mm 2 and 0 mm (0 – 0.5) mm for the control group (P < 0.001). For the subarticular osteophytes, the area and boundary length was 1.0 mm 2 (0 – 4.4) mm 2 and 1.4 mm (0 – 6.5) mm for patients with OA compared to 0 mm 2 (0 – 0.5) mm 2 and 0 mm (0 – 0.5) mm for the control group (P < 0.001). Conclusion As expected, both marginal- and subarticular osteophytes at the femoral head, were more frequent and larger in patients with OA than in the control group. However, in the control group, subarticular osteophytes were more prevalent than expected from the minor osteophytic changes at the femoral head margin, which may suggest that subarticular osteophytes are an early degenerative phenomenon that ultimately might develop into clinical osteoarthritis.


2019 ◽  
Vol 37 (11) ◽  
pp. 2348-2357 ◽  
Author(s):  
Xin‐Yuan Wang ◽  
Bing‐Xuan Hua ◽  
Chang Jiang ◽  
Heng‐Feng Yuan ◽  
Liang Zhu ◽  
...  

e-GIGI ◽  
2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Priska T. Mambu ◽  
Pieter L. Suling ◽  
Aurelia S. R. Supit

Abstract: Smokers can be found in almost all groups of people worldwide since cigarettes can be obtained easily anywhere and have been addicted by adult smokers. Leukoedema is one of the lesions in oral cavity that most often appears in smokers. This study was aimed to obtain the description of leukoedema cases among smokers. This was a literature review study. This study used previous studies or reports related to leukoedema in smokers. There were 13 literatures in this study consisting of 9 cross-sectional studies, 3 cohort studies, and 1 case control study. The results showed that leukoedema lesions were more common in smokers than in those who consumed tobacco. Leukoedema was closely related to the duration of smoking and the frequency of smoking in a day. Leukoedema was also more common in men than in women, and was often found bilaterally on the buccal mucosa. In conclusion, leucoedema was most common in cigarette smokers and was related to duration of smoking, frequency of smoking per day, and sex. It was often found bilaterally on the buccal mucosa.Keywords: smokers, leukoedema Abstrak: Perokok ditemukan pada hampir semua kelompok masyarakat di dunia. Leukoedema merupakan salah satu lesi dalam rongga mulut yang paling sering muncul pada perokok. Penelitian ini bertujuan untuk mengetahui gambaran leukoedema pada perokok. Jenis penelitian ialah studi pustaka. Penelitian ini menggunakan topik terkait leukoedema pada perokok dari penelitian-penelitian sebelumnya. Pustaka yang diulas dan dipelajari dalam penelitian ini sebanyak 13 pustaka, terdiri dari 9 cross-sectional study, 3 cohort study, dan 1 case control study. Hasil penelitian ini memperlihatkan bahwa lesi leukoedema lebih sering ditemukan pada perokok dibandingkan yang tidak merokok meskipun mengonsumsi tembakau. Leukoedema erat hubungannya dengan lama kebiasaan merokok dan frekuensi merokok yang dilakukan dalam sehari. Leukoedema juga lebih sering ditemukan pada laki-laki dibandingkan perempuan, dan sering ditemukan pada mukosa bukal secara bilateral. Simpulan penelitian ini ialah leukoedema sering didapatkan pada perokok dan berhubungan erat dengan kebiasaan merokok, frekuensi merokok, jenis kelamin, dengan lokasi mukosa bukal bilateral.Kata kunci: perokok, leukoedema


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