Increased risk of sudden sensory neural hearing loss in patients with rheumatoid arthritis: a longitudinal follow-up study using a national sample cohort

2018 ◽  
Vol 38 (3) ◽  
pp. 683-689 ◽  
Author(s):  
Sang-Yeon Lee ◽  
Il Gyu Kong ◽  
Dong Jun Oh ◽  
Hyo Geun Choi
Keyword(s):  
Rheumatoid Arthritis ◽  
Hearing Loss ◽  
National Sample ◽  
Follow Up Study ◽  
Increased Risk ◽  
Sensory Neural ◽  
Sensory Neural Hearing Loss

scholarly journals Increased Risk of Sudden Sensory Neural Hearing Loss in Osteoporosis: A Longitudinal Follow-Up Study

2018 ◽  
Vol 103 (8) ◽  
pp. 3103-3109 ◽  
Author(s):  
So Young Kim ◽  
Il Gyu Kong ◽  
Hyun Lim ◽  
Hyo Geun Choi
Keyword(s):  
Hearing Loss ◽  
The Elderly ◽  
National Sample ◽  
Control Group ◽  
Cox Proportional Hazard ◽  
Hazard Ratios ◽  
Increased Risk ◽  
Korean National Health Insurance ◽  
Sensory Neural ◽  
Sensory Neural Hearing Loss

Abstract Context The results of a previous population cohort study suggested an association between osteoporosis and sudden sensory neural hearing loss (SSNHL). Objectives To use a nationwide cohort in the Korean population to investigate the risk of SSNHL in patients with osteoporosis. Design, Setting, and Participants Data entered from 2002 to 2013 were collected from the Korean National Health Insurance Service-National Sample Cohort. A total of 68,241 patients with osteoporosis aged ≥50 years were matched with 68,241 control individuals. The crude (simple) and adjusted hazard ratios (HRs) of SSNHL in those with osteoporosis were analyzed using the Cox proportional hazard model. A subgroup analysis was performed according to age and sex. Results The risk of SSNHL was greater in the osteoporosis group than in the control group (adjusted HR, 1.56; 95% CI, 1.37 to 1.78; P < 0.001). The risk of SSNHL in those with osteoporosis was greater in patients aged <60 years, regardless of sex. Women aged ≥60 years had a higher HR for SSNHL in the presence of osteoporosis (women aged 60 to 69 years: adjusted HR, 1.67; 95% CI, 1.34 to 2.08; P < 0.001; women aged ≥70 years: adjusted HR, 1.90; 95% CI, 1.29 to 2.79; P < 0.001). Conclusions The risk of SSNHL was greater for patients with osteoporosis aged ≥50 years. Middle-age adults, as well as the elderly, are at an increased risk of SSNHL in the presence of osteoporosis.

Results of Surgical Repair of Inapparent Perilymph Fistulas

1986 ◽  
Vol 95 (3_part_1) ◽  
pp. 344-346 ◽  
Author(s):  
G. Joseph Parell ◽  
Gary D. Becker
Keyword(s):  
Hearing Loss ◽  
Surgical Technique ◽  
Surgical Repair ◽  
Conductive Hearing Loss ◽  
Knowing That ◽  
Sensory Neural ◽  
Tissue Grafts ◽  
Conductive Hearing ◽  
Sensory Neural Hearing Loss

In patients who are thought to have a perilymph (PL) fistula, careful inspection of the round and oval windows during exploratory tympanotomy may be normal. The decision must then be made either to terminate the procedure—knowing that the patient's symptoms will probably continue or deteriorate—or to repair both windows as if PL fistulas were present, risking further damage to the inner ear. From a series of 14 patients explored for possible PL fistulas, we report on 6 patients with preoperative diagnoses of PL fistula, based on history, physical examination, and audiometry. Symptoms resulting from trauma were present from 10 days to 23 years before surgery. During exploratory tympanotomy, no fistulas were evident; however, both the oval and round windows were repaired with tissue grafts. Follow up—for 1 to 5 years—revealed that vertigo was relieved in all patients. Postoperatively, one patient had a mild conductive hearing loss; yet no patient sustained a sensory neural hearing loss. We conclude that patch grafting of both the oval and round windows is a safe and effective method of treating suspected, but inapparent fistulas. Patient selection, surgical technique, and results shall be detailed.

scholarly journals Evaluation of the increased risk of spine fracture in patients with mood disorder compared with matched controls: a longitudinal follow-up study using a national sample cohort in Korea

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e027581
Author(s):  
So Young Kim ◽  
Chanyang Min ◽  
Bumjung Park ◽  
Miyoung Kim ◽  
Hyo Geun Choi
Keyword(s):  
Mood Disorder ◽  
National Sample ◽  
Spine Fracture ◽  
Secondary Outcome ◽  
Control Group ◽  
Follow Up Study ◽  
Increased Risk ◽  
History Of ◽  
Age And Sex

ObjectiveTo evaluate the risk of spine fracture in patients with mood disorder using a nationwide cohort.DesignA longitudinal follow-up study.SettingClaims data for the population ≥20 years of age were collected from 2002 to 2013 for the Korean National Health Insurance Service-National Sample Cohort.ParticipantsA total of 60 140 individuals with mood disorder were matched with 240 560 individuals (control group) for age, sex, income, region of residence and osteoporosis.InterventionsIn both the mood disorder and control groups, the history of spine fracture was evaluated. The International Classification of Diseases 10th Revision codes for mood disorder (F31–F39) and spine fracture (S220 and S320) were included.Primary and secondary outcome measuresThe univariable and multivariable HRs and 95% CIs of spine fracture for patients with mood disorder were analysed using a stratified Cox proportional hazards model. Subgroup analyses were conducted according to the history of osteoporosis, age and sex.ResultsApproximately 3.3% (2011/60 140) of patients in the mood disorder group and 2.8% (6795/240 560) of individuals in the control group had spine fracture (p<0.001). The mood disorder group demonstrated a higher adjusted HR for spine fracture than the control group (multivariable HR=1.10, 95% CI 1.04 to 1.15, p<0.001). The participants without osteoporosis showed a higher HR of mood disorder for spine fracture than the control participants (multivariable HR=1.25, 95% CI 1.14 to 1.37, p<0.001). According to age and sex, this result was consistent in subgroups of women aged 20–39 and 40–59 years and men aged ≥60 years.ConclusionThe risk of spine fracture was increased in patients with mood disorder. The potential risk of spine fracture needs to be evaluated when managing patients with mood disorder.

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