Rosmarinic acid attenuated SIN-1-induced cytotoxicity in HepG2 cells through the HO-1 induction and radical scavenging activity

2013 ◽  
Vol 22 (2) ◽  
pp. 549-556 ◽  
Author(s):  
Chang Hyun Jin ◽  
Hee Sun Yang ◽  
Dae Seong Choi ◽  
Myung Woo Byun ◽  
Wang Geun Kim ◽  
...  
Keyword(s):  
Rosmarinic Acid ◽  
Hepg2 Cells ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity

scholarly journals Concentrating rosmarinic acid from Orthosiphon aristatus extract for high antioxidative candies

2021 ◽  
Vol 45 (1) ◽  
pp. 118-128
Author(s):  
Jin Ru Lim ◽  
Lee Suan Chua
Keyword(s):  
Health Promotion ◽  
Antioxidant Capacity ◽  
Rosmarinic Acid ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Herbal Ingredient ◽  
Beneficial Property ◽  
Chromatographic Profiles ◽  
Good Agreement

Extraction and fractionation were carried out to concentrate the rosmarinic acid from Orthosiphon aristatus in order to increase the value of herbal candy formulated using polyphenolic rich extract. The herb was extracted and fractionated in column chromatography, and then analyzed by LC-MS/MS. The collected plant fractions with similar chromatographic profiles were combined and determined for antioxidant capacities expressed in radical scavenging activity. The results showed that the antioxidant capacity was in good agreement with the concentration of rosmarinic acid in the combined fractions. The combined fraction II showed the highest rosmarinic acid content, 3.8%w/w and the highest antioxidant capacity (IC50=14.922 ppm). The incorporation of rosmarinic acid rich extract into candy formulation did not statistically affect the antioxidant capacity. Hence, the rosmarinic acid rich extract could be another choice of ingredient to enhance the beneficial property of candies. Candy is another form of carrier to deliver herbal ingredient for health promotion.

scholarly journals The Relationship between Main Polyphenol Components and Free Radical Scavenging Activity of Selected Medicinal Plants

2018 ◽  
Vol 10 (03) ◽  
Author(s):  
S. Dagnon ◽  
D. Bojilov ◽  
M. Docheva ◽  
A. Edreva
Keyword(s):  
Rosmarinic Acid ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Chemical Characterization ◽  
Scavenging Activity ◽  
Extraction Solvent ◽  
Cultivated Species ◽  
The Relationship ◽  
Dpph Radical Scavenging

This study investigates the relationships between the main polyphenols and DPPH radical scavenging activity (RSA) in extracts from some of the most common wild and cultivated species from the Achillea millefolium group, Mentha, Chenopodium botrys, Clinopodium vulgare and Artemisia vulgaris. Another aspect of the study is the effects of choosing an extraction solvent, highlighting the importance of selecting an appropriate one for obtaining extracts with maximum manifested bioactivity. Chemical characterization of compounds is performed. It is based on HPLC-PDA fingerprint profiles, obtained from 70% aqueous methanol extracts. Hydroxycinnamic acids, glycosides of luteolin (LG), apigenin (AG), their aglycones and methoxyflavones are found to be the most abundant components, which have the highest impact on radical scavenging activity (RSA) of the extracts. The data allow supposing high correlation relationships between caffeoylquinic acids and RSA of extracts from four A. millefolium group species and cv. Proa. Cl. vulgare methanol extract, rich in rosmarinic acid, LG and AG, showed the highest RSA with IC50 10.37μg.mL-1. In contrast, extracts of Ch. botrys which lack phenolic acids, contain low amount of glycosides and are rich in methoxyflavone aglycones, possess very weak RSA. For multicomponent analysis, our data suggest 70% methanol as the most appropriate solvent for extraction of compounds belonging to the polyphenol complex. Based on the high quantities of rosmarinic acid, luteolin and apigenin glycosides, 66% ethanol solvent is found to be the best choice for medicinal consumption extracts.

Phenolic constituents of Crithmum maritimum and their radical scavenging activity

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
S Ngom ◽  
L Breant ◽  
C Antheaume ◽  
C Minker ◽  
A Leick ◽  
...  
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Phenolic Constituents

Free radical scavenging activity of ethanolic extracts from some Apiacean species

Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
B Nickavar ◽  
FS Abolhasani ◽  
M Kamalinejad ◽  
MR Reza Khani ◽  
F Mojab
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Ethanolic Extracts

Effect of Heavy Metals on Phenolic Content and Free Radical Scavenging Activity of Ocimum Tenuiflorum L

2012 ◽  
Vol 2 (3) ◽  
pp. 14-16 ◽  
Author(s):  
G. K. Dwivedi G. K. Dwivedi ◽  
◽  
K. Upadhyay K. Upadhyay ◽  
A. K. Mishra A. K. Mishra ◽  
Arvind Kumar Singh
Keyword(s):  
Heavy Metals ◽  
Free Radical ◽  
Phenolic Content ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Ocimum Tenuiflorum
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