Biological activities of fermented soybean paste (Doenjang) prepared using germinated soybeans and germinated black soybeans during fermentation

2014 ◽  
Vol 23 (5) ◽  
pp. 1533-1540 ◽  
Author(s):  
Hyeong-Eun Kim ◽  
Yong-Suk Kim
Keyword(s):  
Biological Activities ◽  
Fermented Soybean ◽  
Soybean Paste

scholarly journals Cheonggukjang-Specific Component 1,3-Diphenyl-2-propanone as A Novel PPARα/γ Dual Agonist: An In Vitro and In Silico Study

2021 ◽  
Vol 22 (19) ◽  
pp. 10884
Author(s):  
Radha Arulkumar ◽  
Hee-Jin Jung ◽  
Sang-Gyun Noh ◽  
Daeui Park ◽  
Hae-Young Chung
Keyword(s):  
In Silico ◽  
Dietary Intervention ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Fermented Soybean ◽  
Soybean Paste ◽  
In Silico Studies ◽  
Dual Agonist ◽  
In Silico Tools

Background: Cheonggukjang is a traditional fermented soybean paste that is mostly consumed in Korea. However, the biological activities of Cheonggukjang specific compounds have not been studied. Thus, we aimed to discover a novel dual agonist for PPARα/γ from dietary sources such as Cheonggukjang specific volatile compounds and explore the potential role of PPARα/γ dual agonists using in vitro and in silico tools. Methods: A total of 35 compounds were selected from non-fermented and fermented soybean products cultured with Bacillus subtilis, namely Cheonggukjang, for analysis by in vitro and in silico studies. Results: Molecular docking results showed that 1,3-diphenyl-2-propanone (DPP) had the lowest docking score for activating PPARα (1K7L) and PPARγ (3DZY) with non-toxic effects. Moreover, DPP significantly increased the transcriptional activities of both PPARα and PPARγ and highly activated its expression in Ac2F liver cells, in vitro. Here, we demonstrated for the first time that DPP can act as a dual agonist of PPARα/γ using in vitro and in silico tools. Conclusions: The Cheonggukjang-specific compound DPP could be a novel PPARα/γ dual agonist and it is warranted to determine the therapeutic potential of PPARα/γ activation by dietary intervention and/or supplementation in the treatment of metabolic disorders without causing any adverse effects.

Studies on Physiological and Functional Properties of Susijang, Fermented Soybean Paste

2007 ◽  
Vol 36 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Bog-Mi Ryu ◽  
Jung-Suk Kim ◽  
Min-Hee Park ◽  
Gap-Soon Moon
Keyword(s):  
Functional Properties ◽  
Fermented Soybean ◽  
Soybean Paste

Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors

2010 ◽  
Vol 20 (3) ◽  
pp. 1162-1164 ◽  
Author(s):  
Jun-Seong Park ◽  
Dong Hyun Kim ◽  
Jae Kyoung Lee ◽  
Jin Young Lee ◽  
Duck Hee Kim ◽  
...  
Keyword(s):  
Fermented Soybean ◽  
Melanin Formation ◽  
Soybean Paste

scholarly journals Growth Inhibition of Helicobacter pylori by Ingestion of Fermented Soybean Paste

2007 ◽  
Vol 17 (12) ◽  
pp. 1695-1700
Author(s):  
Hyung-Rak Kim ◽  
Young-Hyu Kim ◽  
Seong-Chan Park ◽  
Mi-Sun Kim ◽  
Keun-Sik Baik ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Growth Inhibition ◽  
Fermented Soybean ◽  
Soybean Paste

Comparison of a descriptive analysis and instrumental measurements (electronic nose and electronic tongue) for the sensory profiling of Korean fermented soybean paste (doenjang )

2017 ◽  
Vol 32 (5) ◽  
pp. e12282 ◽  
Author(s):  
Hee Yeon Jung ◽  
Han Sub Kwak ◽  
Mi Jeong Kim ◽  
Yoonsook Kim ◽  
Kwang-Ok Kim ◽  
...  
Keyword(s):  
Electronic Nose ◽  
Descriptive Analysis ◽  
Electronic Tongue ◽  
Fermented Soybean ◽  
Soybean Paste
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