Clinical and molecular epidemiology of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a long-term study from Japan

2010 ◽  
Vol 30 (1) ◽  
pp. 83-87 ◽  
Author(s):  
Y. Chong ◽  
H. Yakushiji ◽  
Y. Ito ◽  
T. Kamimura
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Molecular Epidemiology ◽  
Term Study ◽  
Long Term Study ◽  
Extended Spectrum

scholarly journals Long-term study of the frequency of Escherichia coli and Klebsiella pneumoniae isolates producing extended-spectrum β-lactamases

2005 ◽  
Vol 11 (8) ◽  
pp. 625-631 ◽  
Author(s):  
L. Romero ◽  
L. López ◽  
J. Rodríguez-Baño ◽  
J. Ramón Hernández ◽  
L. Martínez-Martínez ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Term Study ◽  
Long Term Study ◽  
Extended Spectrum

Community spread of extended-spectrum β-lactamase-producing Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis: a long-term study in Japan

2013 ◽  
Vol 62 (7) ◽  
pp. 1038-1043 ◽  
Author(s):  
Yong Chong ◽  
Shinji Shimoda ◽  
Hiroko Yakushiji ◽  
Yoshikiyo Ito ◽  
Toshihiro Miyamoto ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Proteus Mirabilis ◽  
Epidemiological Data ◽  
Detection Rates ◽  
E Coli ◽  
Long Term Study ◽  
Extended Spectrum ◽  
Few Data

Community-acquired infections caused by extended-spectrum β-lactamase (ESBL)-producing bacteria, particularly CTX-M-producing Escherichia coli, are a rising concern worldwide. There are few data from Japan on the acquisition of ESBLs in the community or the influx of these bacteria into hospitals. Therefore, we examined the prevalence of ESBL carriage in outpatients, in order to estimate the spread of ESBLs in community settings. We analysed bacterial isolates from outpatient samples at our institution over a 9-year period from 2003 to 2011, with respect to epidemiological data on ESBL-producing bacteria and their genotypic features. Out of 5137 isolates, 321 (6.3 %) were ESBL producers, including E. coli, Klebsiella pneumoniae and Proteus mirabilis. The detection rates of the ESBL-producing isolates gradually increased and reached 14.3, 8.7 and 19.6 % for E. coli, K. pneumoniae and P. mirabilis strains, respectively, in 2011. Genotyping analysis showed that many of the strains produced multiple β-lactamases, including TEM, SHV and CTX-M, rather than just CTX-M. The CTX-M-9 group was dominant among the CTX-M genotypes; further, the CTX-M-1 and M-2 groups were also detected (~30 %). This is believed to be the first report from Japan showing a definite increase in ESBL detection in outpatients. In addition, our findings suggest the simultaneous community spread of diverse ESBL genotypes, not an expansion of particular ESBL genes.

scholarly journals Nationwide Study of the Prevalence, Characteristics, and Molecular Epidemiology of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in France

2007 ◽  
Vol 52 (2) ◽  
pp. 786-789 ◽  
Author(s):  
Muriel Galas ◽  
Jean-Winoc Decousser ◽  
Nelly Breton ◽  
Thierry Godard ◽  
Pierre Yves Allouch ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Molecular Epidemiology ◽  
Molecular Analysis ◽  
Enterobacter Aerogenes ◽  
Nationwide Study ◽  
E Coli ◽  
Extended Spectrum ◽  
Prevalent Species

ABSTRACT Among 10,872 isolates of Enterobacteriaceae from a nationwide study of 88 French hospitals in 2005, 169 (1.7%) expressed an extended-spectrum β-lactamase. The most prevalent species were Escherichia coli (48.5%), Enterobacter aerogenes (23.7%), and Klebsiella pneumoniae (14.8%). Molecular analysis underlined the polyclonal spread of CTX-M-expressing E. coli, primarily isolates of the CTX-M-1 subgroup.

scholarly journals Evaluation of homeopathic and biotherapic treatments in a swine farm to control Escherichia coli infection: a long term study

2021 ◽  
Vol 11 (40) ◽  
pp. 136-137
Author(s):  
Cidéli de Paula Coelho ◽  
Francisco Rafael Soto ◽  
Erlete Rosalina Vuaden ◽  
Priscilla Anne Melville ◽  
Andrea Micke Moreno ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Virulence Factors ◽  
Antimicrobial Treatment ◽  
Enterotoxigenic Escherichia Coli ◽  
Control Group ◽  
Swine Farm ◽  
Term Study ◽  
Mato Grosso ◽  
Long Term Study

Background: Escherichia coli is the most important etiological agent in neonatal diarrhea in swine, and Enterotoxigenic Escherichia coli (ETEC) is the most commonly isolated. Regarding to virulence factors, five main types of fimbriae were already described in swine samples: F4 (K88), F5 (K99), F6 (987P), F18 and F41. Thermolabile (LT) and thermostable enterotoxins (ST), as well as shiga-like toxin or verotoxin (Stx2) are also found in isolates of swine origin, related to diarrhoea process. Methods: This long term study has been developed in a swine farm (Mato Grosso, Brazil), in which 93 piglets were studied and 184 fecal samples were evaluated in two steps, with the aim to search the presence of Escherichia coli and to prepare a specific biotherapic medicine. Each step had one year of interval each other. Concurrently, for each step, a detailed anamnesis was made for choosing the ideal homeopathic medication for each step (Phosphorus 30 CH and Pulsatilla 30 CH, respectively). In each step, four groups consisting of 11-12 piglets and the respective primiparous mother pig were formed, and the treatments happened simultaneously: control group (antimicrobial treatment, the same used in the swine farm), homeopathic medication, E. coli biotherapic and homeopathic medication associated to biotherapic. The medications were made according to the Brazilian Homeopathic Pharmacopeia and the treatment lasted 12 days. After 24 days, in the weaning, the weight gain of each bath was also evaluated. Considering both steps, the research of virulence factors and enterotoxins was carried out in 99 Escherichia coli colonies through Polymerase Chain Reaction - PCR. Results: In both steps, the homeopathy treated groups passed from 75.0% of diarrhea incidence to 8.3% at the end of the treatment (p

scholarly journals Surveillance of Community-Based Reservoirs Reveals the Presence of CTX-M, Imported AmpC, and OXA-30 β-Lactamases in Urine Isolates of Klebsiella pneumoniae and Escherichia coli in a U.S. Community

2008 ◽  
Vol 52 (10) ◽  
pp. 3814-3816 ◽  
Author(s):  
Nancy D. Hanson ◽  
Ellen Smith Moland ◽  
S. G. Hong ◽  
Katie Propst ◽  
Deborah J. Novak ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Long Term Care ◽  
Outpatient Clinics ◽  
Community Based ◽  
Term Care ◽  
Extended Spectrum ◽  
Care Facilities

ABSTRACT β-Lactamases produced by urine isolates from patients in long-term care facilities (LTCFs), outpatient, clinics, and one hospital in a U.S. community were characterized. A total of 1.3% of all Escherichia coli and Klebsiella pneumoniae isolates collected from patients in 30 LTCFs and various outpatient clinics produced extended-spectrum β-lactamases (ESBLs) and/or imported AmpC β-lactamases.

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