Bacterial vaginosis-associated vaginal microbiota is an age-independent risk factor for Chlamydia trachomatis, Mycoplasma genitalium and Trichomonas vaginalis infections in low-risk women, St. Petersburg, Russia

Background There is a paucity of studies looking at associations between Mycoplasma genitalium and pelvic inflammatory disease (PID). The objectives of this study were to estimate the prevalence of M. genitalium in women attending a sexual health service in New Zealand and secondly to examine for an association of M. genitalium with PID. Methods: Women consecutively attending the service for a sexual health screen (Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis) were recruited to establish a baseline prevalence of M. genitalium. An extra cervical swab was taken for the detection of M. genitalium. Recruitment of additional women with a clinical diagnosis of PID continued until a sufficient sample size was obtained to examine the association of PID with M. genitalium. Women in the baseline sample without PID were used as the control group. Results: The control group included 250 women, with M. genitalium diagnosed in 8.7% (95% CI 5.8–12.9%) and C. trachomatis in 9.9% (95% CI 6.8–14.2%). Ninety-one women were recruited with PID; M. genitalium was diagnosed in 9.9% (95% CI 5.3–17.7%) and C. trachomatis in 27.5% (95% CI 19.4–37.4%). Multivariate analysis using clinically relevant variables showed that a diagnosis of C. trachomatis (OR 2.44, 95% CI 1.24–4.81) but not M. genitalium (OR 0.91, 95% CI 0.38–2.20) was significantly associated with a PID diagnosis. Conclusions: M. genitalium was almost as commonly diagnosed as C. trachomatis in this population. C. trachomatis was the only infection that was significantly associated with PID.

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Microbiological Characteristics of Chlamydia trachomatis and Neisseria gonorrhoeae Infections in South African Women

Journal of Clinical Microbiology ◽

10.1128/jcm.02848-15 ◽

2015 ◽

Vol 54 (1) ◽

pp. 200-203 ◽

Cited By ~ 12

Author(s):

Jan Henk Dubbink ◽

Dewi J. de Waaij ◽

Myrte Bos ◽

Lisette van der Eem ◽

Cécile Bébéar ◽

...

Keyword(s):

Chlamydia Trachomatis ◽

Neisseria Gonorrhoeae ◽

Trichomonas Vaginalis ◽

Mycoplasma Genitalium ◽

Cross Sectional Study ◽

African Women ◽

Transmitted Infection ◽

Cross Sectional ◽

Content Type ◽

South African Women

We analyzed data of 263 women with at least one genital or anorectal sexually transmitted infection from a cross-sectional study conducted in rural South Africa. We provide new insights concerning the concurrence ofChlamydia trachomatis,Neisseria gonorrhoeae,Mycoplasma genitalium, andTrichomonas vaginalisinfections as well as the characteristics of bacterial loads.

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Midpregnancy genitourinary tract infection with Chlamydia trachomatis: Association with subsequent preterm delivery in women with bacterial vaginosis and Trichomonas vaginalis

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2005.08.054 ◽

2006 ◽

Vol 194 (2) ◽

pp. 493-500 ◽

Cited By ~ 36

Author(s):

William W. Andrews ◽

Mark A. Klebanoff ◽

Elizabeth A. Thom ◽

John C. Hauth ◽

J. Christopher Carey ◽

...

Keyword(s):

Chlamydia Trachomatis ◽

Tract Infection ◽

Bacterial Vaginosis ◽

Preterm Delivery ◽

Trichomonas Vaginalis ◽

Genitourinary Tract

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Evaluation of Association between Vaginal Infections and High-Risk Human Papillomavirus Types in Female Sex Workers in Spain

ISRN Obstetrics and Gynecology ◽

10.5402/2012/240190 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 15

Author(s):

C. Rodriguez-Cerdeira ◽

E. Sanchez-Blanco ◽

A. Alba

Keyword(s):

Human Papillomavirus ◽

High Risk ◽

Bacterial Vaginosis ◽

Sex Workers ◽

Trichomonas Vaginalis ◽

Female Sex Workers ◽

Vaginal Microbiota ◽

Transmitted Infection ◽

Female Sex ◽

Associated Lesions

Background. Infection with and persistence of high-risk human papillomavirus (HR-HPV) are the strongest risk factors for cervical cancer. In addition, other genital microorganisms may also be involved in the progression of HPV-associated lesions. Objetive. To evaluate the association of the vaginal microbiota (Candida spp., Trichomonas vaginalis, and bacterial vaginosis) with HR-HPV infection in Spanish female sex workers (FSWs). Methods. This cross-sectional study involved 208 (FSWs; age, 18–49 years) who visited a sexually transmitted infection (STI) information and prevention center (SERGAS) between January 2010 and December 2011. Face-to-face interviews were carried out. Cervical and vaginal samples were examined for human papillomavirus (HPV), Trichomonas vaginalis, Candida spp., and microorganisms related to bacterial vaginosis (BV). Results. HR-HPV was found to be significantly associated with BV in FSWs with positive results for HPV16-related types (31, 33, 35, and 52). T. vaginalis was isolated in FSWs with the following HR-HPVs: 18, 45, 66, and 68. Candida spp. were isolated only in FSWs with HPV 18-positive infection. Conclusion. We demonstrate a significant prevalence of HR-HPVs in FSWs with disturbances in the vaginal microbiota.

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Nocturia is an age-independent risk factor for hip-fractures in men

Neurourology and Urodynamics ◽

10.1002/nau.20712 ◽

2009 ◽

Vol 28 (8) ◽

pp. 949-952 ◽

Cited By ~ 58

Author(s):

Christian Temml ◽

Anton Ponholzer ◽

Georg Gutjahr ◽

Ingrid Berger ◽

Martin Marszalek ◽

...

Keyword(s):

Risk Factor ◽

Hip Fractures ◽

Independent Risk Factor ◽

Age Independent

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The Pregravid Vascular Risk Factor Profile of Low-Risk Women Who Develop Pregnancy Outcomes That Predict Future Cardiovascular Disease

Women's Health Reports ◽

10.1089/whr.2021.0006 ◽

2021 ◽

Vol 2 (1) ◽

pp. 62-70

Author(s):

Roslyn Mainland ◽

Shi Wu Wen ◽

Hongzhuan Tan ◽

Shujin Zhou ◽

Chang Ye ◽

...

Keyword(s):

Cardiovascular Disease ◽

Risk Factor ◽

Pregnancy Outcomes ◽

Vascular Risk Factor ◽

Low Risk ◽

Vascular Risk ◽

Risk Factor Profile ◽

Low Risk Women

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INCIDENCE OF SEXUALLY TRANSMITTED INFECTIONS: LOCAL STUDY IN UKRAINE

World Science ◽

10.31435/rsglobal_ws/30082018/6059 ◽

2018 ◽

Vol 2 (8(36)) ◽

pp. 4-7

Author(s):

Fedorych P. V. ◽

Mavrov G. I.

Keyword(s):

Human Papillomavirus ◽

Chlamydia Trachomatis ◽

Sexually Transmitted Infections ◽

Trichomonas Vaginalis ◽

Ureaplasma Urealyticum ◽

Mycoplasma Hominis ◽

Mycoplasma Genitalium ◽

Local Study ◽

Sexually Transmitted ◽

Clinically Significant

Introduction.The structure of incidence of sexually transmitted infections is changing constantly. Information on such changes supports correct planning of clinical and diagnostic activities of institutions providing specialized medical care by qualified specialists.Objective:to investigate the prevalence of sexually transmitted infections with pathogens clinically significant to the genitourinary system in Ukraine and at the local level.Materials and methods. Polymerase chain reaction was used to test the biological material obtained from the genitourinary clinical specimens from subjects with sexually transmitted infections, who underwent clinical and laboratory examinations in Oleksandrivsk Clinical Hospital (Kyiv, Ukraine) for Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum, Trichomonas vaginalis, Human papillomavirus, and Neisseria gonorrhoea. During 2017, 607 subjects of both genders, including 295 (48.6%) females and 312 (51.4%) males, were examined. Their mean age was 32±3.5.Findings. Chlamydia trachomatis was found in 159 (26.2%) of 607 examined subjects – 85 males and 74 females. Mycoplasma hominis was found in 122 of 585 (21.1%) examined subjects – 64 males and 58 females. Mycoplasma genitalium, respectively, in 17 (6.62%) of 258 subjects – 6 males and 11 females. Ureaplasma urealyticum was found in the largest number of subjects (305, i.e. in 48.77% of 601 examined subjects) – 157 males and 148 females. Trichomonas vaginalis was found in 28 (5.23%) of 535 subjects – 15 males and 13 females. Human papillomavirus was found in 158 of 297 (53.2%) examined subjects – 88 males and 70 females. Neisseria gonorrhea was found in 33 of 297 (8.45%) subjects – 8 males and 25 females.Conclusions. As suggested by the local study of the sexually transmitted infections incidence in Ukraine, the most clinically significant for the genitourinary system are Human papillomavirus (53.2%), Ureaplasma urealyticum (48.77%), Chlamydia trachomatis (26.2%) and Mycoplasma hominis (21.1%). Therefore, tests for these pathogens in the specified region is currently the most appropriate during diagnostic examinations and counselling of subjects with genitourinary infections.

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