Securing the surgical field for mobilization of right-sided colon cancer using the duodenum-first multidirectional approach in laparoscopic surgery

Abstract Background The aim of this study was to compare the short-term outcomes of the duodenum-first multidirectional approach (DMA) in laparoscopic right colectomy with those of the conventional medial approach to assess its safety and feasibility. Methods This retrospective study enrolled 120 patients who had laparoscopic surgery for right-sided colon cancer in our institution between April 2013 and December 2019. Fifty-four patients underwent colectomy using the multidirectional approach; among these, 20 underwent the DMA and 34 underwent the caudal-first multidirectional approach (CMA). Sixty-six patients underwent the conventional medial approach. Complications within 30 days of surgery were compared between the groups. Results There were 54 patients in the multidirectional group [29 females, median age 72 years (range 36–91 years)] and 66 in the medial group [42 females, median age 72 years (range 41–91 years)]. Total operative time was significantly shorter in multidirectional approach patients than conventional medial approach patients (208 min vs. 271 min; p = 0.01) and significantly shorter in patients who underwent the DMA compared to the CMA (201 min vs. 269 min; p < 0.001). Operative time for the mobilization procedure was also significantly shorter in patients who underwent the DMA (131 min vs. 181 min; p < 0.001). Blood loss and incidence of postoperative complications did not differ. In 77 patients with advanced T3/T4 tumors, the DMA, CMA, and conventional medial approach were performed in 13, 21, and 43 patients, respectively. Total operative time and operative time of the mobilization procedure were significantly shorter in patients undergoing DMA. Blood loss and incidence of postoperative complications did not differ. R0 resection was achieved in all patients with advanced tumors. Conclusions The DMA in laparoscopic right colectomy is safe and feasible and can achieve R0 resection with a shorter operative time than the conventional medial approach, even in patients with advanced tumors.

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P496 Feasibility and safety of single incision laparoscopic surgery for patients with complex Crohn’s disease

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjz203.625 ◽

2020 ◽

Vol 14 (Supplement_1) ◽

pp. S433-S433

Author(s):

Y LI ◽

B Liu ◽

D Yao ◽

L Zheng ◽

Z Zhou ◽

...

Keyword(s):

Laparoscopic Surgery ◽

Postoperative Complications ◽

Blood Loss ◽

Hospital Stay ◽

Simple Group ◽

Complex Disease ◽

Operative Time ◽

Single Incision ◽

Single Incision Laparoscopic Surgery ◽

Complex Group

Abstract Background Single-incision laparoscopic surgery (SILS) offers excellent cosmetic results compared with conventional multi-port laparoscopic surgery. Recently, this technique has been applied to Crohn’s disease (CD); however, the application of a laparoscopic approach for complex CD, which involves abscess formation, fistula formation, and recurrent CD, is controversial. The aim of this study was to investigate the feasibility and safety of SILS for patients with the complex disease and to compare its clinical results in patients with complex disease. Methods We investigated the feasibility and safety of SILS in sixty patients who underwent SILS for CD were divided into two groups: those with the complex disease (complex group, n = 30), and those with a simple disease (simple group, n = 30). The perioperative data were analysed and compared between the groups. Results The mean operative time and blood loss were 130.5 ± 28.3 min (range 105–166 min) and 230 ± 58 ml (range 116–410 ml) in the complex group, and 113.4 ± 21.5 min (range 95–151 min) and 72 ± 19ml (range 58–115 ml) in the simple group. There were no significant differences in the operative time between the two groups (p = 0.083, >0.05), but the blood loss was significantly greater in the cases of complex group (p = 0.025, <0.05). Two patients in the complex group required conversion to open surgery for a retroperitoneal fistula and recurrent CD disease. There were no conversions in the simple group. The frequency of postoperative complications was similar in the two groups. The length of the hospital stay was also similar in the two groups. Although the rate of conversion tended to be higher in the complex group, the rate of postoperative complications and length of hospital stay did not differ significantly between the groups (p = 0.061, >0.05). Conclusion SILS may be feasible and safe for carefully selected patients with complex CD.

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Functional and early oncological results in 2D vs 3D laparoscopic prostatectomy

Urologicheskie vedomosti ◽

10.17816/uroved835-10 ◽

2018 ◽

Vol 8 (3) ◽

pp. 5-10

Author(s):

Oleg A. Bogomolov ◽

Mikhail I. Shkolnik ◽

Andrej D. Belov ◽

Svetlana A. Sidorova ◽

Denis G. Prokhorov ◽

...

Keyword(s):

Prostate Cancer ◽

Postoperative Complications ◽

Blood Loss ◽

Operative Time ◽

Clinical Stage ◽

Functional Results ◽

Localized Prostate Cancer ◽

Total Operative Time ◽

Laparoscopic Prostatectomy ◽

Estimated Blood Loss

Aim. To evaluate functional and early oncologic results with 2D and 3D laparoscopic prostatectomy in patients with localized prostate cancer. Materials and methods. In 2016 to 2017, 124 laparoscopic radical prostatectomies were performed for localized prostate cancer, 71 using 2D-HD and 53 using 3D-HD laparoscopic systems (Karl Storz). Data on total operative time, time required for prostatectomy and for anastomosis, estimated blood loss, intraoperative and early postoperative complications (Clavien-Dindo grade), early functional results, surgical margins, upgrading of clinical stage, and frequency of biochemical recurrence were recorded. Results. The total operative was significantly higher in the 2D than in the 3D group (152 min [range 100–192 min] vs 126 min [90–154 min]), (p < 0.05). The shorter time in the 3D group was achieved by a decrease in the anastomosis time (38 ± 4 min vs 26 ± 4 min, p < 0.05). Significant blood loss was significantly greater in the 2D group (240 ± 80 ml vs 190 ± 70 ml, p < 0.05). The two groups did not differ significantly in terms of the incidence and severity of postoperative complications. Conclusion. Compared with traditional 2D devices, using stereoscopic 3D laparoscopic devices for prostatectomy reduces total operative time, particularly during the reconstructive stage, as well as the volume of intraoperative blood loss. Additional prospective, randomized trials and longer postoperative follow-up are needed to confirm these findings.

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A learning curve in using organ retractor for single-incision laparoscopic right colectomy

Scientific Reports ◽

10.1038/s41598-021-86168-4 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Toshio Shiraishi ◽

Tetsuro Tominaga ◽

Takashi Nonaka ◽

Kiyoaki Hamada ◽

Masato Araki ◽

...

Keyword(s):

Colon Cancer ◽

Laparoscopic Surgery ◽

Blood Loss ◽

Learning Curve ◽

Single Incision ◽

Operation Time ◽

Perioperative Outcomes ◽

Single Incision Laparoscopic Surgery ◽

Right Colon ◽

Right Colon Cancer

AbstractSingle-incision laparoscopic surgery (SILS) has the potential to improve perioperative outcomes, including less postoperative pain, shorter operation time, less blood loss, and shorter hospital stay. However, SILS is technically difficult and needs a longer learning curve. Between April 2016 and September 2019, a total of 198 patients with clinical stage I/II right colon cancer underwent curative resection. In the case of the SILS approach, an organ retractor was usually used to overcome SILS-specific restrictions. The patients were divided into two groups by surgical approach: the SILS with organ retractor group (SILS-O, n = 33) and the conventional laparoscopic surgery group (LAC, n = 165). Clinical T status was significantly higher in the LAC group (p = 0.016). Operation time was shorter and blood loss was lower in the SILS-O group compared to the LAC group (117 vs. 197 min, p = 0.027; 10 vs. 25 mL, p = 0.024, respectively). In the SILS-O group, surgical outcomes including operation time, blood loss, number of retrieved lymph nodes, and postoperative complications were not significantly different between those performed by experts and by non-experts. Longer operation time (p = 0.041) was significantly associated with complications on univariate and multivariate analyses (odds ratio 2.514, 95%CI 1.047–6.035, p = 0.039). SILS-O was safe and feasible for right colon cancer. There is a potential to shorten the learning curve of SILS using an organ retractor.

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Effects of Preoperative Iodine Administration on Thyroidectomy for Hyperthyroidism: A Systematic Review and Meta-analysis

Otolaryngology ◽

10.1177/0194599819829052 ◽

2019 ◽

Vol 160 (6) ◽

pp. 993-1002 ◽

Cited By ~ 1

Author(s):

Chung-Hsin Tsai ◽

Po-Sheng Yang ◽

Jie-Jen Lee ◽

Tsang-Pai Liu ◽

Chi-Yu Kuo ◽

...

Keyword(s):

Postoperative Complications ◽

Blood Loss ◽

Operative Time ◽

Meta Analysis ◽

Thyroid Volume ◽

Vocal Cord Palsy ◽

Significant Heterogeneity ◽

Intraoperative Blood Loss ◽

Significant Difference ◽

And Control

Objective The current guidelines recommend that potassium iodide be given in the immediate preoperative period for patients with Graves’ disease who are undergoing thyroidectomy. Nonetheless, the evidence behind this recommendation is tenuous. The purpose of this study is to clarify the benefits of preoperative iodine administration from published comparative studies. Data Sources We searched PubMed, Embase, Cochrane, and CINAHL from 1980 to June 2018. Review Methods Studies were included that compared preoperative iodine administration and no premedication before thyroidectomy. For the meta-analysis, studies were pooled with the random-effects model. Results A total of 510 patients were divided into the iodine (n = 223) and control (n = 287) groups from 9 selected studies. Preoperative iodine administration was significantly associated with decreased thyroid vascularity and intraoperative blood loss. Significant heterogeneity was present among studies. We found no significant difference in thyroid volume or operative time. Furthermore, the meta-analysis showed no difference in the risk of postoperative complications, including vocal cord palsy, hypoparathyroidism/hypocalcemia, and hemorrhage or hematoma after thyroidectomy. Conclusion Preoperative iodine administration decreases thyroid vascularity and intraoperative blood loss. Nonetheless, it does not translate to more clinically meaningful differences in terms of operative time and postoperative complications.

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Laparoscopic versus open surgery for gastrointestinal stromal tumor in esophagogastric junction: A multi-center, retrospective cohort analysis with propensity score matching.

Journal of Clinical Oncology ◽

10.1200/jco.2020.38.15_suppl.11534 ◽

2020 ◽

Vol 38 (15_suppl) ◽

pp. 11534-11534

Author(s):

Wenjun Xiong ◽

Tao Chen ◽

Xingyu Feng ◽

Yuting Xu ◽

Jin Wan ◽

...

Keyword(s):

Laparoscopic Surgery ◽

Propensity Score ◽

Blood Loss ◽

Gastrointestinal Stromal Tumor ◽

Propensity Score Matching ◽

Open Surgery ◽

Esophagogastric Junction ◽

Operative Time ◽

Liquid Intake

11534 Background: Laparoscopic resection is increasingly performed for Gastrointestinal stromal tumor (GIST). Nevertheless, laparoscopic approach for the GIST located in the esophagogastric junction (EGJ-GIST) represent a surgical challenge. This study aims to investigate the efficacy of laparoscopic surgery and open procedure for EGJ-GIST through the propensity score matching (PSM) method. Methods: Between April 2006 and April 2018, 1824 patients underwent surgery were finally diagnosed with primary gastric GIST at four medical centers in South China. EGJ-GIST was defined as a GIST with an upper border of less than 5 cm from the EG line. Among them, 228 patients were identified and retrospectively reviewed with regard to clinicopathological characteristics, operative information and long-term outcomes. The PSM methods was used to eliminate the selection bias. Results: After PSM, 102 cases, consisted of 51 laparoscopic (LA) and 51 open surgery (OP), were enrolled. The match factors contained year of surgery, gender, age, BMI, tumor size, mitotic rate, recurrence risk and adjuvant tyrosine kinase inhibitors treatment. The LA group was superior to the OP group in operative time (108.5±56.5 vs. 169.3±79.0 min, P <0.001), blood loss (54.6±81.9 vs. 104.9±156.4 ml, P = 0.042), time to liquid intake (3.1±1.8 vs. 4.3±2.2 d, P = 0.003), hospital stay (6.0±2.3 vs. 9.9±8.1, P = 0.001), and postoperative complication (5.9% vs. 25.5%, P = 0.006). The median follow-up was 55 (range, 2-153) months in the entire cohort. No significant differences were detected in either the relapse-free survival (RFS, P = 0.109) or overall survival (OS, P = 0.113) between two groups. The 1-, 3-, and 5-year RFS in the LA and OP groups were 100.0%, 95.5%, 91.0% and 100.0%, 90.8%, 85.7%, respectively. The 1-, 3-, and 5-year OS in the LA and OP group were 100%, 95.6%, 91.3% and 100.0%, 91.1%, 85.4%, respectively. Conclusions: Laparoscopic surgery for EGJ-GIST is associated with the advantages of shorter operative time, reduced blood loss, shorter time to liquid intake and shorter length of stay, all without compromising post-operative outcomes and long-term survival.

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Impact of Procedure Time of Preceding Endoscopic Submucosal Dissection on the Difficulty of Laparoscopic Rectal Surgery

10.21203/rs.3.rs-44867/v1 ◽

2020 ◽

Author(s):

Hiroaki Nozawa ◽

Kazushige Kawai ◽

Kazuhito Sasaki ◽

Shigenobu Emoto ◽

Koji Murono ◽

...

Keyword(s):

Rectal Cancer ◽

Laparoscopic Surgery ◽

Blood Loss ◽

Operative Time ◽

Anal Verge ◽

Rectal Surgery ◽

Tumor Location ◽

Intraoperative Blood Loss ◽

Procedure Time ◽

Laparoscopic Rectal Surgery

Abstract Background Endoscopic treatment for gastrointestinal cancer can cause inflammation, edema, and fibrosis formation in the surrounding tissue. Recently, we reported that preceding endoscopic treatment increased the volume of intraoperative blood loss and slightly prolonged the operative time of laparoscopic surgery for rectal cancer. In this study, we addressed which factors, including endoscopic submucosal dissection (ESD)- related parameters, affect the difficulty of laparoscopic rectal surgery. Methods We retrospectively reviewed 24 consecutive patients who underwent ESD followed by laparoscopic surgery for rectal cancer in our hospital. Short-term surgical outcomes were evaluated by intraoperative blood loss and operative time for laparoscopic surgery. The correlations between the surgical outcomes and preoperative parameter were analyzed by scatter diagrams and multiple linear regression analyses. Results The patient cohort comprised 12 men and 12 women. The median distance between primary cancer and anal verge was 7 cm. The median procedure time of ESD was 120 minutes (21 available cases). The scatter diagram graph revealed a positive correlation between the ESD procedure time and estimated blood loss during rectal surgery (rs = 0.26). There was no association between the ESD procedure time and operative time for rectal surgery. Based on multiple linear regression analyses, the ESD procedure time (p = 0.007) and tumor location from the anal verge (p = 0.046) were independently predictive of intraoperative blood loss. On the other hand, only tumor location was found an independent predictor of surgical time (p = 0.014). Conclusions A long session of ESD for rectal cancer may make subsequent laparoscopic surgery difficult based on intraoperative blood loss.

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Laparoscopic Spleen-Preserving Distal Pancreatectomy (LSPDP) versus Open Spleen-Preserving Distal Pancreatectomy (OSPDP): A Comparative Study

Canadian Journal of Gastroenterology and Hepatology ◽

10.1155/2019/9367868 ◽

2019 ◽

Vol 2019 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Jing Huang ◽

Dipesh Kumar Yadav ◽

Chaojie Xiong ◽

Ye Sheng ◽

Xinhua’ Zhou ◽

...

Keyword(s):

Postoperative Complications ◽

Blood Loss ◽

Hospital Stay ◽

Pancreatic Fistula ◽

Distal Pancreatectomy ◽

Operative Time ◽

Malignant Tumors ◽

Low Grade ◽

Intraoperative Blood Loss ◽

Spleen Preserving

Objective. To compare outcomes between laparoscopic spleen-preserving distal pancreatectomy (LSPDP) and open spleen-preserving distal pancreatectomy (OSPDP) for treatment of benign and low-grade malignant tumors of the pancreas and evaluate feasibility and safety of LSPDP. Methods. The clinical data of 53 cases of LSPDP and 44 cases of OSPDP performed between January 2008 and August 2018 were retrospectively analyzed. The clinical outcomes between the two groups were compared. Results. There was no significant difference in preoperative data between the two groups. However, the LSPDP group had statistically significant shorter operative time (145.3±55.9 versus 184.7±33.5, P=0.03) and lesser intraoperative blood loss (150.6±180.8 versus 253.5±76.2, P=0.03) than that of the OSPDP group. Moreover, the LSPDP group also had statistically significant earlier passing of first flatus (2.2±1.4 versus 3.1±1.9, P=0.01), earlier diet intake (2.3±1.8 versus 3.4±2.0, P=0.01), and shorter hospital stay (6.2±7.2 versus 8.8±9.3, 0.04) than that of the OSPDP group. However, postoperative pancreatic fistula (P=0.64) and total postoperative complications (P=0.59) were not significantly different between the groups. The rate of pancreatic fistula and total postoperative complications occurred in 62.5% and 64.5%, respectively, in LSPDP group and, similarly, 70% and 70.0%, respectively, in OSPDP group. Conclusion. This study confirms that LSPDP is safe, feasible, and superior to OSPDP in terms of operative time, intraoperative blood loss, hospital stay, and postoperative recovery. Hence, it is worth popularizing LSPDP for benign and low-grade malignant tumors of the pancreas.

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Risk factors for postoperative complications of a randomized clinical trial: Laparoscopic versus open surgery with D3 lymphadenectomy for stage II/III colon cancer (JCOG0404).

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.3_suppl.717 ◽

2015 ◽

Vol 33 (3_suppl) ◽

pp. 717-717

Author(s):

Yusuke Nishizawa ◽

Masaaki Ito ◽

Norio Saito ◽

Hiroshi Katayama ◽

Junki Mizusawa ◽

...

Keyword(s):

Risk Factors ◽

Clinical Trial ◽

Colon Cancer ◽

Multivariate Analysis ◽

Laparoscopic Surgery ◽

Postoperative Complications ◽

Open Surgery ◽

Clinical Stage ◽

Stage Ii ◽

Colon Cancers

717 Background: A randomized controlled trial to confirm the non-inferiority of laparoscopic surgery to open surgery for clinical stage II/III colon cancers in terms of overall survival was conducted. In this ancillary study, we explored the risk factors for postoperative complications of laparoscopic surgery and open surgery. Methods: Eligibility criteria included colon cancer; tumor located in the cecum, ascending, sigmoid, or rectosigmoid colon; T3 or T4 without involvement of other organs; N0-2; and M0. Postoperative complications which were observed from the end of the operation to discharge were graded according to the CTCAE 3.0. Multivariate analysis was performed using logistic regression model. Results: Between October 2004 and March 2009, a total of 1,057 patients from 30 Japanese centers were registered. By per-protocol set, 524 patients underwent open surgery (OPEN) and 533 patients underwent laparoscopic surgery (LAP). Proportion of any grade (G) complication was 18.3% (OPEN 22.3%, LAP 14.3%), G2–G3 was 12.9% (OPEN 13.9%, LAP 11.8%), G3 was 5.3% (OPEN 6.9%, LAP 3.8%) and G4 was none. Postoperative complications (G2-G3) included leakage (OPEN 2.1%, LAP 1.9%), ileus (OPEN:1.5%, LAP:0.9%), and wound complication (OPEN: 0.2%, LAP: none). Multivariate analysis revealed that risk factors for postoperative complications were operation times 240 min or more (p=0.0019, odds ratio [OR] 2.01 [95% CI: 1.30-3.13]) and open surgery (p=0.0001, OR 2.05 [95% CI: 1.41-2.98]). Conclusions: Operation times more than 240 min and open surgery were considered to be the risk factors for postoperative complications for clinical stage II/III colon cancers. Clinical trial information: C000000105.

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Upper Pole Nephrectomy: A Simplified Technique Using a Retroperitoneal Laparoscopic Approach

Case Reports in Urology ◽

10.1155/2011/570790 ◽

2011 ◽

Vol 2011 ◽

pp. 1-3

Author(s):

Joana Pereira ◽

Angélica Osório ◽

João Moreira-Pinto ◽

José Cidade-Rodrigues ◽

Carlos Enes ◽

...

Keyword(s):

Postoperative Complications ◽

Blood Loss ◽

Operative Time ◽

Laparoscopic Approach ◽

Renal Tissue ◽

Vascular Supply ◽

Ectopic Ureter ◽

Lower Pole ◽

Renal Hilum ◽

Collecting System

Objective. To describe a simplified technique already used in our institution for several years in the open heminephrectomy for duplication anomalies, now performed through a retroperitoneal laparoscopic approach.Methods. The technique begins with upper pole parenchyma incision since the demarcation between the affected upper moiety and the healthy lower pole is easily established. The dissection proceeds until the urothelium of the collecting system is entered, which will guide further excision, minimizing damage of the surrounding structures. The vascular supply is then identified since the upper pole is attached to the remaining renal parenchyma only by these structures that can be safely divided. Dissection and division of the ectopic ureter is carried next.Results. The operative time was 188 minutes. The blood loss was not significant, and there were no other complications during the procedure. The patient was discharged home 48 hours after the procedure, without any early or late postoperative complications.Conclusion. We believe this simplified technique allows a safer excision of nonfunctioning upper pole renal tissue by avoiding the initial dissection of the renal hilum, which associated with the known advantages of a laparoscopic approach makes us consider it the procedure of choice for upper pole nephrectomy in children.

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Introduction of gasless laparoscopic surgery as a minimally invasive procedure for endometrial cancer and its usefulness from the viewpoint of the learning curve

World Journal of Surgical Oncology ◽

10.1186/s12957-021-02453-6 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Hiroe Ito ◽

Tetsuya Moritake ◽

Fumitoshi Terauchi ◽

Keiichi Isaka

Keyword(s):

Endometrial Cancer ◽

Laparoscopic Surgery ◽

Blood Loss ◽

Learning Curve ◽

Hospital Stay ◽

Open Surgery ◽

Operative Time ◽

Perioperative Complications ◽

Survival Rates ◽

Significant Difference

Abstract Background We investigated the usefulness of gasless laparoscopic surgery (GLS) using a subcutaneous abdominal wall lifting method for endometrial cancer. Methods We studied 105 patients with early endometrial cancer who underwent GLS (55) or open surgery (50). A uterine manipulator was used in all GLS cases. We compared operative time, blood loss, number of lymph nodes removed, hospital stay, perioperative complications, cases converted to laparotomy, and recurrence and survival rates. We also studied the learning curve and proficiency of GLS. Results The GLS group had significantly longer operative time (265 vs. 191 min), reduced blood loss (184 vs. 425 mL), shorter hospital stay (9.9 vs. 17.6 days), and fewer postoperative complications (1.8 vs. 12.0%) than the open group. No case was converted to laparotomy. Disease-free and overall survival rates at 4 years postoperatively (GLS vs. open groups) were 98.0 versus 97.8 and 100 versus 95.7%, respectively, and there was no significant difference between the groups. Regarding the learning curve for GLS, two different phases were observed in approximately 10 cases. Operator 2, who was not accustomed to laparoscopic surgery, showed a significant reduction in operative time in the later phase 2. Conclusions GLS for endometrial cancer results in less bleeding, shorter hospital stay, and fewer complications than open surgery. Recurrence and survival rates were not significantly different from those of open surgery. This technique may be introduced in a short time for operators who are skilled at open surgery but not used to laparoscopic surgery.

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