Measurement of nonlinear property of artery wall using remote cyclic actuation

2006 ◽  
Vol 33 (3) ◽  
pp. 143-151 ◽  
Author(s):  
Hideyuki Hasegawa ◽  
Hiroshi Kanai
Circulation ◽  
1996 ◽  
Vol 94 (9) ◽  
pp. 2248-2253 ◽  
Author(s):  
K.A. Roberts ◽  
A.A. Rezai ◽  
K.E. Pinkerton ◽  
J.C. Rutledge

2001 ◽  
Vol 19 (4) ◽  
pp. 703-711 ◽  
Author(s):  
Damiano Rizzoni ◽  
Maria Lorenza Muiesan ◽  
Massimo Salvetti ◽  
Maurizio Castellano ◽  
Giorgio Bettoni ◽  
...  

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1535.1-1535
Author(s):  
W. Fan ◽  
J. Zhu ◽  
P. Yu ◽  
L. Yu ◽  
X. Wang ◽  
...  

Background:Carotid contrast enhanced ultrasound (CEUS) is used for diagnosis and activity determination of patients with Takayasu’s arteritis (TA). However, very little is known about the carotid CEUS features of TA complicated with Behcet’s disease (BD).Objectives:This study reports the carotid CEUS features in cases of TA complicated with BD (TBD).Methods:A total of 10 carotid CEUS examinations were performed on 4 patients of TBD. 10 TA patients complicated with no rheumatoid disease were included as control group. For each carotid artery lesion, the carotid CEUS features was graded as follows: Grade 0, artery wall shows no microbubbles, Grade 1, artery wall shows limited or moderate microbubbles, Grade 2, artery wall shows severe microbubbles.Results:2/10 patients in TBD group has oral ulcer during the CEUS examination, while all the other patients included in our study showed no clinical symptoms related to active TA or BD. The carotid wall thickness was greater of CEUS grade 2 than grade 1 in both group(TBD: 2.62±0.74mm vs 1.66±0.22mm,p=0.001; TA:1.84±0.31mm vs 1.53±0.5mm,p=0.136). The carotid wall thickness was significantly greater in TBD group than TA group, but there was no significant differences between the two groups in clinical data and CEUS grade (table 1).Table 1.Clinical data and carotid CEUS features of both groupsTBDTApAge (year)32.5±3.4430.5±9.20.487Male320.605ESR (mm/h)4(2, 10)7(3.5, 11)0.406CRP (mg/L)6.42(0.55, 15.38)0.58(0.44, 5.05)0.168Wall thickness (mm)2.10±0.701.67±0.440.030CEUS grade 29120.527Conclusion:This study first shows carotid CEUS features in cases of TA complicated with BD, which may help with the comprehensive treatments of the disease.Disclosure of Interests: :None declared


2017 ◽  
Vol 3 (9) ◽  
pp. 443-446
Author(s):  
Takuro Nishimura ◽  
Masahiko Goya ◽  
Shinya Shiohira ◽  
Takakatsu Yoshitake ◽  
Yasuhiro Shirai ◽  
...  

2007 ◽  
Vol 293 (3) ◽  
pp. H1997-H2003 ◽  
Author(s):  
Xiang-Yang Zhu ◽  
Michael D. Bentley ◽  
Alejandro R. Chade ◽  
Erik L. Ritman ◽  
Amir Lerman ◽  
...  

Changes in the structure of the artery wall commence shortly after exposure to cardiovascular risk factors, such as hypercholesterolemia (HC), but may be difficult to detect. The ability to study vascular wall structure could be helpful in evaluation of the factors that instigate atherosclerosis and its pathomechanisms. The present study tested the hypothesis that early morphological changes in coronary arteries of hypercholesterolemic (HC) pigs can be detected using the novel X-ray contrast agent OsO4 and three-dimensional micro-computed tomography (CT). Two groups of pigs were studied after they were fed a normal or an HC (2% cholesterol) diet for 12 wk. Hearts were harvested, coronary arteries were injected with 1% OsO4 solution, and cardiac samples (6-μm-thick) were scanned by micro-CT. Layers of the epicardial coronary artery wall, early lesions, and perivascular OsO4 accumulation were determined. Leakage of OsO4 from myocardial microvessels was used to assess vascular permeability, which was correlated with immunoreactivity of vascular endothelial growth factor in corresponding histological cross sections. OsO4 enhanced the visualization of coronary artery wall layers and facilitated detection of early lesions in HC in longitudinal tomographic sections of vascular segments. Increased density of perivascular OsO4 in HC was correlated with increased vascular endothelial growth factor expression and suggested increased microvascular permeability. The use of OsO4 as a contrast agent in micro-CT allows three-dimensional visualization of coronary artery wall structure, early lesion formation, and changes in vascular permeability. Therefore, this technique can be a useful tool in atherosclerosis research.


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