scholarly journals Improved PrEP Awareness and Use among Trans Women in San Francisco, California

2021 ◽  
Author(s):  
Erin C. Wilson ◽  
Christopher J. Hernandez ◽  
Susan Scheer ◽  
Dillon Trujillo ◽  
Sean Arayasirikul ◽  
...  
Keyword(s):  
San Francisco ◽  
Anal Intercourse ◽  
Receptive Anal Intercourse ◽  
The Past ◽  
National Hiv Behavioral Surveillance ◽  
Trans Women ◽  
Gender Based ◽  
Prep Awareness ◽  
Almost All ◽  
Exposure Prophylaxis

AbstractTransgender women face a serious risk of HIV infection. Despite this, there is limited knowledge and use of Pre-exposure prophylaxis (PrEP). We measured the continuity of prevention across services in the PrEP cascade and correlates of PrEP use among trans women in San Francisco enrolled in the 2019/20 National HIV Behavioral Surveillance Study. Knowledge and use of PrEP among trans women in San Francisco increased in recent years; almost all (94.0%) had heard about PrEP, 64.7% had discussed PrEP with a healthcare provider, and 44.8% had taken PrEP in the past 12 months. PrEP use was associated with participation in a PrEP demonstration project (aOR = 31.44, p = 0.001) and condomless receptive anal intercourse (aOR = 3.63, p = 0.024). Injection drug use was negatively associated (aOR = 0.19, p = 0.014). Efforts are needed to combat the gender-based stigma and discrimination faced by trans women, which can result in avoidance and mistrust of the medical system.

Characterizing PrEP Awareness and Interest Among Filipina Transgender Women

2020 ◽  
Vol 32 (3) ◽  
pp. 212-228
Author(s):  
Arjee J. Restar ◽  
Alexander Adia ◽  
Susan Cu-Uvin ◽  
Don Operario
Keyword(s):  
Health Care Providers ◽  
The Philippines ◽  
Care Providers ◽  
Hiv Knowledge ◽  
Early Adopters ◽  
Trans Women ◽  
Hiv Acquisition ◽  
Prep Awareness ◽  
Almost All ◽  
Exposure Prophylaxis

Pre-exposure prophylaxis (PrEP) can efficaciously avert HIV acquisition for individuals at risk, including transgender individuals (trans) in the Philippines. We conducted multivariate logistic regression procedures in an online sample of Filipina trans women (n = 139) to examine associations of PrEP awareness. In this sample, 53% of Filipina trans women were unaware of PrEP, but almost all (93%) expressed interest in taking PrEP once learning about it. Greater odds of PrEP awareness was associated with discussion of HIV services with their health care providers, higher HIV knowledge, and discussion of PrEP among trans friends. Lower odds of PrEP awareness was associated with reporting being currently unemployed. The findings underscore a subset of trans women who might be early adopters of PrEP, and highlight PrEP inequities among trans women most marginalized, including those who are unemployed and have engaged in sex work.

HIV pre-exposure prophylaxis (PrEP) awareness and acceptability among trans women: a review

AIDS Care ◽  
2019 ◽  
Vol 31 (10) ◽  
pp. 1234-1240 ◽  
Author(s):  
Nathália Pacífico de Carvalho ◽  
Cássia Cristina Pinto Mendicino ◽  
Raissa Carolina Fonseca Cândido ◽  
Denyr Jeferson Dutra Alecrim ◽  
Cristiane Aparecida Menezes de Pádua
Keyword(s):  
Trans Women ◽  
Prep Awareness ◽  
Exposure Prophylaxis

scholarly journals Gender-based discrimination and unprotected receptive anal intercourse among transgender women in Brazil: A mixed methods study

PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0194306 ◽  
Author(s):  
Laio Magno ◽  
Inês Dourado ◽  
Luís Augusto V. da Silva ◽  
Sandra Brignol ◽  
Leila Amorim ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Anal Intercourse ◽  
Transgender Women ◽  
Mixed Methods Study ◽  
Receptive Anal Intercourse ◽  
Unprotected Receptive Anal Intercourse ◽  
Gender Based

Comparing non-occupational post-exposure prophylaxis drug regimens for HIV: insights from a linked HIV surveillance system

Sexual Health ◽  
2017 ◽  
Vol 14 (2) ◽  
pp. 179 ◽  
Author(s):  
Anna B. Pierce ◽  
Carol El-Hayek ◽  
Damien McCarthy ◽  
Jude Armishaw ◽  
Kerrie Watson ◽  
...  
Keyword(s):  
Anal Intercourse ◽  
Post Exposure Prophylaxis ◽  
Receptive Anal Intercourse ◽  
Hiv Diagnosis ◽  
Hiv Surveillance ◽  
Post Exposure ◽  
Hiv Serostatus ◽  
Drug Regimens ◽  
Sex With Men ◽  
Exposure Prophylaxis

Background International non-occupational post-exposure prophylaxis (NPEP) guidelines recommend routine use of three drug NPEP regimens, despite absence of evidence for greater prevention efficacy compared with two drug regimens. This study examines the potential for excess HIV seroconversions among high-risk men who have sex with men (MSM) reporting receptive anal intercourse with a source of unknown HIV serostatus (RAIU) following a two-drug versus a three-drug NPEP regimen. Methods: Data for MSM in the Victorian NPEP service database between 10 August 2005 and 31 December 2012 were linked with all Victorian HIV notifications up to 31 December 2013. The primary outcome was NPEP failure following NPEP presentation among MSM reporting RAIU, stratified by the number of drugs prescribed. Results: Among 1482 MSM reporting 2002 episodes of RAIU and prescribed two- or three-drug NPEP, 70 seroconverted to HIV, but only 19 were considered possible NPEP failures. HIV diagnosis incidence among men reporting RAIU was 1.2/100 person years (PY) (95%CI = 1.0–1.6); 1.1/100 PY (95%CI = 0.8–1.4) among MSM prescribed two drugs and 2.2/100 PY (95%CI = 1.4–3.7) among MSM prescribed three drugs (P < 0.01). Of the 19 possible NPEP failures, 13 (0.7%) were prescribed two drugs and six (2.7%) three drugs (P < 0.001). Conclusions: This study suggests that two-drug NPEP regimens do not result in excess seroconversions compared with three-drug regimens when used following RAIU. Clinical services should carefully consider their use of three drug NPEP and whether resources might be better invested in other prevention strategies, particularly pre-exposure prophylaxis (PrEP).

scholarly journals 163. High Prevalence of Urogenital and Rectal Mycoplasma genitalium in U.S. MSM with a History of STIs in the Last Year

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S98-S99
Author(s):  
Emma D Bainbridge ◽  
Olusegun O Soge ◽  
Cole Grabow ◽  
Stephanie Cohen ◽  
Julia C Dombrowski ◽  
...  
Keyword(s):  
Drug Resistance ◽  
San Francisco ◽  
Mycoplasma Genitalium ◽  
Nucleic Acid Amplification ◽  
Research Support ◽  
The Past ◽  
Increased Risk ◽  
Exposure Prophylaxis ◽  
Living With Hiv

Abstract Background M. genitalium (M. gen) is an under-recognized sexually transmitted bacterial pathogen that causes 15-25% of nongonococcal urethritis (NGU) in men. Asymptomatic M. gen may serve as a reservoir, lead to transmission to sexual contacts, and drive the development of drug resistance. M. gen may be associated with an increased risk of HIV acquisition, as seen in some studies. Data are limited on M. gen prevalence among U.S. men who have sex with men (MSM) living with HIV or HIV-uninfected and on pre-exposure prophylaxis (PrEP). Methods We analyzed baseline prevalence of urogenital and rectal M. gen using the Aptima Mycoplasma genitalium nucleic acid amplification test in participants enrolled in DoxyPEP, an ongoing randomized, open label trial of the effectiveness of doxycycline post-exposure prophylaxis (PEP) on incidence of gonorrhea, chlamydia, and early syphilis among MSM and transgender women living with HIV or on PrEP in San Francisco and Seattle (NCT03980223). Participants completing at least one follow up visit were also assessed for M. gen persistence, clearance, and incidence. Testing was at regular intervals and not symptom driven. Results This analysis included 122 men; 34% with HIV and 66% on PrEP. In the prior 12 months, 18.9% had a diagnosis of syphilis, 58.2% chlamydia, and 63.9% gonorrhea. At baseline, M. gen was present in at least one site in 24%; 9% in the urine and 16% in the rectum, with 1 testing positive at both sites. M. gen presence was not associated with age, ethnicity, race, HIV status, number of partners in the past 3 months, or bacterial STI in the past 3 months. 65 participants had follow up tests a median of 9.1 months after baseline (IQR 7.8-9.8); among 7 participants with urogenital M. gen at baseline, M. gen cleared in 6 and persisted in 1. Among 11 participants with rectal M. gen at baseline, M. gen cleared in 4 cleared and persisted in 7. At follow up, M. gen was detected in 2 urine and 9 rectal specimens in those previously negative at these sites. Figure 1. Baseline prevalence of urogenital and rectal M. genitalium in MSM at high risk for STIs enrolled in DoxyPEP Figure 2. Detection of urogenital and rectal M. genitalium among participants with baseline and follow up testing Conclusion In this cohort of MSM with a recent diagnosis of a bacterial STI, routine testing identified urogenital or rectal M. gen in 24% of participants at baseline and 31% at either baseline or follow-up. The association of persistent M. gen with the risk for subsequent symptomatic infection and drug resistance merits further investigation. Disclosures Emma D. Bainbridge, MD, MPH, Hologic (Grant/Research Support) Olusegun O. Soge, PhD, Hologic Inc. (Grant/Research Support)SpeeDx Inc. (Grant/Research Support) Annie Luetkemeyer, MD, Cepheid (Grant/Research Support)Hologic (Grant/Research Support)Mayne Pharma (Grant/Research Support)

Awareness and uptake of pre-exposure prophylaxis for HIV among low-income, HIV-negative heterosexuals in San Francisco

2021 ◽  
pp. 095646242098666
Author(s):  
Daphine Namara ◽  
Hui Xie ◽  
Desmond Miller ◽  
Danielle Veloso ◽  
Willi McFarland
Keyword(s):  
San Francisco ◽  
Low Income ◽  
Educational Materials ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Left Behind ◽  
Prep Implementation ◽  
Prep Awareness ◽  
Exposure Prophylaxis ◽  
Hiv Negative

We examined pre-exposure prophylaxis (PrEP) awareness and uptake among low-income heterosexual men and women in San Francisco in 2019. Of 294 HIV-negative survey participants, 42.5% were aware of PrEP. Few women (12.5%) and men (8.9%) had discussed PrEP with a healthcare provider; 3.8% of women and 0% of men had used PrEP in the last year. White participants (adjusted odds ratio (aOR) 5.39, 95% CI 1.02, 28.56), women (aOR 2.19, 95% CI 1.30, 3.70), and age 60 years or above (aOR 4.00, 95% CI 1.12, 14.34) had greater odds of being aware of PrEP. Testing for HIV or sexually transmitted infection in the past year was marginally associated with a greater PrEP awareness. Our findings reveal gaps in PrEP implementation associated with social disparities among low-income heterosexuals. Testing services and targeted promotional and educational materials are needed lest high-risk, low-income populations are left behind in San Francisco’s aggressive “Getting to Zero” efforts.

scholarly journals Pre-Exposure Prophylaxis (PrEP) Awareness Is Low Among Heterosexual People of Color Who Might Benefit From PrEP in Philadelphia

2019 ◽  
Vol 10 ◽  
pp. 215013271984738 ◽  
Author(s):  
Alexis M. Roth ◽  
Nguyen K. Tran ◽  
Brogan L. Piecara ◽  
Jennifer Shinefeld ◽  
Kathleen A. Brady
Keyword(s):  
Sociodemographic Factors ◽  
People Of Color ◽  
Care Utilization ◽  
Metropolitan Statistical Area ◽  
Medical Visit ◽  
Medical Provider ◽  
Chi Square ◽  
National Hiv Behavioral Surveillance ◽  
Prep Awareness ◽  
Exposure Prophylaxis

Introduction: We assessed awareness of pre-exposure prophylaxis (PrEP) among HIV-negative Black and Latinx persons living in the Philadelphia Metropolitan Statistical Area. Methods: Using chi-square and Wilcoxon rank-sum tests, we analyzed data from the 2016 heterosexual cycle of the National HIV Behavioral Surveillance system to assess how sociodemographic factors, health care utilization, and risk behaviors affected PrEP awareness. Results: Participants (n = 472) were predominately Black, non-Hispanic (88.1%) with a median age of 41.5 years. Most participants reported having a usual source of medical care (92.1%) and seeing a medical provider within 12 months (87.0%). However, PrEP awareness was low in this sample (4.9%) and was lower among those who had a medical visit compared with those who had not ( P < .01). Conclusion: Current Centers for Disease Control and Prevention clinical guidelines suggest that providers counsel high-risk patients about PrEP. Our data suggest that this is not happening with people of color in Philadelphia. Interventions targeting medical providers working with HIV-risk people of color may be appropriate.

scholarly journals Internet-Based Methods May Reach Higher-Risk Men who have Sex with Men Not Reached Through Venue-Based Sampling§

2012 ◽  
Vol 6 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Travis Sanchez ◽  
Amanda Smith ◽  
Damian Denson ◽  
Elizabeth DiNenno ◽  
Amy Lansky
Keyword(s):  
Hiv Infection ◽  
Anal Intercourse ◽  
Unprotected Anal Intercourse ◽  
Web Based ◽  
Behavioral Surveillance ◽  
The Past ◽  
National Hiv Behavioral Surveillance ◽  
Hiv Serostatus ◽  
Sex With Men ◽  
College Educated

Background: Internet-based sampling methods may reach men who have sex with men (MSM) who don’t attend physical venues frequented by MSM and may be at higher risk of HIV infection. Methods: Multivariate logistic regression was used to examine characteristics of adult MSM participants in 2 studies conducted in the same 5 U.S. cities: the 2003-2005 National HIV Behavioral Surveillance System (NHBS) which used sampling from physical MSM venues (e.g., bars, clubs) and the 2007 Web-based HIV Behavioral Surveillance (WHBS) pilot which used sampling through online banner advertisements. Results: Among 5024 WHBS MSM, 95% attended a physical MSM venue in the past 12 months, and 75% attended weekly. WHBS MSM who were black, aged 18-21 years, not college educated, bisexual- or heterosexual-identifying, and reported unknown HIV serostatus were less likely to have attended a physical MSM venue in the past 12 months (all p<0.01). Compared to NHBS MSM, WHBS MSM were more likely to be white, younger, college-educated, report unknown HIV serostatus, report unprotected anal intercourse with a casual partner, and have first met that partner online (all p<0.0001). WHBS MSM were less likely to have been under the influence of drugs during most recent sex (p=0.01) or not know their sex partner’s HIV serostatus (p<0.0001). Conclusions: Many MSM recruited online also attended physical venues, but attendance varied by sub-group. Participants in WHBS and NHBS differed, and WHBS may represent a group of MSM at higher risk of HIV infection. These findings suggest that an internet-based method may be a useful supplement to NHBS.

scholarly journals The Classification of the Persistent Infection Risk for Human Papillomavirus among HIV-Negative Men Who Have Sex with Men: Trajectory Model Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Bingxue Huang ◽  
Duolao Wang ◽  
Christiana Papamichael ◽  
Tian Tian ◽  
Xiaoqing Tuo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Condom Use ◽  
Anal Intercourse ◽  
Infection Risk ◽  
Receptive Anal Intercourse ◽  
Anal Sex ◽  
The Past ◽  
Sex With Men ◽  
Hiv Negative

Objective. To classify the infection risk of human papillomavirus (HPV) among human immunodeficiency virus- (HIV-) negative men who have sex with men (MSM) using group-based trajectory modeling (GBTM). Methods. This study collected data on demographic and sexual behavior characteristics by questionnaires at semiannual visits from March 1st, 2016 to December 31th, 2017. Researchers collected anal exfoliated cells to finish HPV testing and blood samples to finish HIV testing at baseline and follow-up visits. Accumulative infection numbers of different types of HPV as the primary outcome and the follow-up visits as the independent predicator to build a GBTM model. Results. There were 500 potentially eligible HIV-negative participants at baseline, 361 (72.2%) of whom were included in this study after screening. Three trajectory groups were identified as the best-fitted GBTM model. Trajectory 1, defined as decreased group (DG) accounted for 44.6% (161/361) of the sample, showed a declining pattern with visits. Trajectory 2, defined as flat group (FG) accounted for 49.6% (179/361) of the sample, showed a flat pattern with visits. Trajectory 3, regarded as the increased group (IG) accounted for 5.8% (21/361) of the sample, showed an uptrend. Compared to the DG, risk factors for the FG included receptive anal intercourse (AOR, 2.24; 95% CI, 1.36-3.71), occasional condom use in anal sex during the past six months (AOR, 1.90; 95% CI, 1.16-3.14), experience of transactional sex with males in the past year (AOR, 3.60; 95% CI, 1.12-11.54), and substance use (AOR, 1.81; 95% CI, 1.08-3.04). Risk factors for the IG included receptive anal intercourse (AOR, 2.81; 95% CI, 1.04-7.70), occasional condom use in anal sex during the past six months (AOR, 3.93; 95% CI, 1.40-11.01), and history of other STIs (AOR, 5.72; 95% CI, 1.40-23.46). Conclusion. The MSM data in this study showed three distinct developmental trajectories (DG, FG, and IG) of HPV infection among HIV-negative MSM, with receptive anal intercourse and occasional condom use in anal sex during the past six months being the risk factors associated with FG and IG.

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