Is family history related to preventive health behaviors and medical management in breast cancer patients?

2005 ◽  
Vol 90 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Lisa Madlensky ◽  
Shirley W. Flatt ◽  
Wayne A. Bardwell ◽  
Cheryl L. Rock ◽  
John P. Pierce ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Health Behaviors ◽  
Cancer Patients ◽  
Medical Management ◽  
Preventive Health ◽  
Breast Cancer Patients ◽  
Preventive Health Behaviors

scholarly journals Evaluating the Effect of Health Education Intervention on the Health Beliefs and Behaviors of First-Degree Female Relatives of Breast Cancer Patients

2021 ◽  
Author(s):  
Sule Olgun ◽  
Berna Dizer
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Health Education ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Patients ◽  
Health Beliefs ◽  
Breast Cancer Patients ◽  
History Of ◽  
And Behaviors

Abstract Background Breast cancer risk increases by 80% in the presence of BRCA1 and BRCA2 gene mutations in the same family. In particular, a woman whose sister or mother has breast cancer has a 2- to 5-fold higher risk of developing breast cancer compared with other women. For this reason, recommendations should have been made regarding breast cancer prevention and/or early detection for women with first-degree family history of breast cancer. Aim The aim of this study was to evaluate the effect of health education, which was provided to first-degree female relatives of breast cancer patients, on their health beliefs and behaviors. Study Design and Methods The study sample included 50 women with a first-degree relative being treated for breast cancer in the chemotherapy and radiotherapy unit of a university hospital. A one-group pretest-posttest design was used. The pretest consisted of the health belief model scale and a questionnaire regarding the women’s sociodemographic information and breast cancer screening behaviors. After the pretest, the patients received health education regarding breast cancer risk factors and screening methods. The posttest was conducted 3 weeks after the education using the same assessment tools. Results After education, there were statistically significant increases in rates of practicing breast self-examination, having clinical breast examinations, and undergoing breast ultrasound/mammography compared with pretest results. Conclusions Health workers should possess knowledge and experience about breast cancer which will enable them to effectively undertake an educational role, especially for high-risk groups such as women with first-degree family history of breast cancer.

Breast-conservation therapy in early-stage breast cancer patients with a positive family history

2002 ◽  
Vol 9 (9) ◽  
pp. 912-919 ◽  
Author(s):  
Georges Vlastos ◽  
Nadeem Q. Mirza ◽  
Funda Meric ◽  
Kelly K. Hunt ◽  
Attiqa N. Mirza ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Early Stage ◽  
Positive Family History ◽  
Breast Conservation ◽  
Breast Conservation Therapy ◽  
Early Stage Breast Cancer ◽  
Breast Cancer Patients

The Importance of Family History in Breast Cancer Patients in Primary Care Setting: a Cross-sectional Study

2017 ◽  
Vol 33 (3) ◽  
pp. 602-609
Author(s):  
Mehtap Kartal ◽  
Nilgun Ozcakar ◽  
Sehnaz Hatipoglu ◽  
Makbule Neslisah Tan ◽  
Azize Dilek Guldal
Keyword(s):  
Breast Cancer ◽  
Primary Care ◽  
Family History ◽  
Cancer Patients ◽  
Care Setting ◽  
Primary Care Setting ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Cross Sectional

Recurrent mutation testing of BRCA1 and BRCA2 in Asian breast cancer patients identify carriers in those with presumed low risk by family history

2014 ◽  
Vol 144 (3) ◽  
pp. 635-642 ◽  
Author(s):  
Peter Choon Eng Kang ◽  
Sze Yee Phuah ◽  
Kavitta Sivanandan ◽  
In Nee Kang ◽  
Eswary Thirthagiri ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Mutation Testing ◽  
Recurrent Mutation ◽  
Low Risk ◽  
Breast Cancer Patients ◽  
Brca1 And Brca2

A Theory-based Mobile Health Physical Activity Intervention for Breast Cancer Patients during Chemotherapy:a Preliminary Evaluation (Preprint)

2020 ◽  
Author(s):  
Zhaohui Geng ◽  
Li Ning ◽  
Lingzhi Cai ◽  
Ying Liu ◽  
Jingting Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Behavior Change ◽  
Health Behaviors ◽  
Cancer Patients ◽  
Mobile Health ◽  
Protective Factor ◽  
Smartphone Application ◽  
Preliminary Evaluation ◽  
Breast Cancer Patients

BACKGROUND Physical activity (PA), known as a modifiable protective factor, provides an approach to sustain physical and psycho-social health for breast cancer patients both during and after treatment. Mobile health (mHealth) application targeted promoting health behaviors demonstrates advantages in behavior tracking, knowledge sharing and social connecting and tailored intervention. However, process of mHealth application (App) development is lack of theoretical basis, restricting its sustainable benefits to cancer survivors. OBJECTIVE To construct a theory-based mHealth PA intervention program, and to determine whether this intervention would improve PA behavior change during chemotherapy for breast cancer patients, thus to capture their perspectives and experiences when participate it. METHODS Social cognitive theory (SCT), self-efficacy theory (SET) and the theory of planned behavior (TPB) are referred to construct mHealth intervention strategies. Smartphone application was chosen to implement a pre-post three-month PA intervention. A mixed method was utilized to test the preliminary effectiveness of MPAP. Quantitative results from online records and self-reported questionnaires were collected after intervention. Qualitative feedback through telephone interviewing was recorded to explore patients’ using experiences. RESULTS “Breast care” smartphone application was developed to improve self-management of breast cancer patients including PA. In the end, five main pages covering 6 functions (information delivering, disease tracking, events reminding based on calendar, online interaction, health behavior recording and self-reported assessment) were displayed in the app. In the preliminary evaluation process, twenty participants were recruited. Based on PA capability assessment and baseline PA evaluation, 12 patients were divided into active group, and 8 patients were grouped in sedentary lifestyle. Within three months, participants’ usage behavior identified at portal site indicated the accumulated app usage time is 40 minutes a week, and average login time of each participant was three times a week. The total PA increased 945.70 MET-min/w with a significant improvement(p=0.040) after 3 months. Walking displayed a significant improvement after intervention (904.20 MET-min/w) (p=0.030). Sedentary mean time declined 210 mins/w. Qualitative results showed satisfaction and willingness of breast cancer patients to use app to manage PA and relevant health behaviors. CONCLUSIONS The theory-based mHealth PA intervention has great potential to enhance breast cancer patients’ PA awareness and engagement, meanwhile to facilitate their PA behavior change.

Mutation analysis of PALB2 in high-risk and lower-risk patients negative for BRCA1 and BRCA2 mutations.

2012 ◽  
Vol 30 (27_suppl) ◽  
pp. 30-30
Author(s):  
Shelly Cummings ◽  
Jenny Peterson ◽  
Elisha Hughes ◽  
Rajesh R. Kaldate ◽  
Sonia Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Genetic Testing ◽  
Family History ◽  
High Risk ◽  
Cancer Patients ◽  
Lower Risk ◽  
Risk Group ◽  
Breast Cancer Patients ◽  
Brca1 And Brca2 ◽  
Palb2 Mutation

30 Background: PALB2 has been identified as a breast cancer susceptibility gene conferring ~ 2-4 fold increased risk of breast cancer. A number of studies have estimated the PALB2 mutation prevalence to range from 0.5% - 2.9% in populations of breast cancer patients. We performed an analysis to determine the PALB2 mutation prevalence in a large U.S. referral testing population. Methods: DNA samples were anonymized from two subsets of patients: 955 early onset breast cancer patients with severe family history, and 524 patients with later onset of breast cancer and/or less severe family history. All patients were negative for deleterious sequence mutations or large rearrangements in BRCA1 and BRCA2. Results: We identified 10 disease associated PALB2 mutations in the high risk group of 955 patients and 2 deleterious PALB2 mutations in the lower risk group of 524 patients. Identified PALB2 mutations included 8 nonsense, 3 frameshift mutations and a splice site mutation. The mutation prevalence for the high risk population was 1.05% (95% C.I., 0.5 -1.92) whereas that for the lower risk population was 0.38% (95% C.I., 0.05-1.37). The observed rate of PALB2 variants of unknown significance (VUS) identified in this study was ~5% (78 VUS were in 75 of the 1479 patients that were tested). Our variant classification program which successfully decreased the VUS rate in BRCA1 and BRCA2 is similarly expected to enhance mutation classification on an on-going basis for PALB2 genetic testing. Conclusions: Genetic testing for PALB2 may be indicated as a reflex test for breast cancer patients who test negative for BRCA1 and BRCA2.

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