Serum 25-hydroxyvitamin D, vitamin A, and lung cancer mortality in the US population: a potential nutrient–nutrient interaction

2012 ◽  
Vol 23 (9) ◽  
pp. 1557-1565 ◽  
Author(s):  
Ting-Yuan David Cheng ◽  
Marian L. Neuhouser
Keyword(s):  
Lung Cancer ◽  
Vitamin A ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Hydroxyvitamin D ◽  
Nutrient Interaction ◽  
The Us ◽  
25 Hydroxyvitamin D

scholarly journals Lung cancer mortality in Europe and the United States between 2000 and 2017: an observational analysis

2021 ◽  
pp. 00311-2021
Author(s):  
Chinmay Jani ◽  
Dominic C Marshall ◽  
Harpreet Singh ◽  
Richard Goodall ◽  
Joseph Shalhoub ◽  
...  
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Mortality Rates ◽  
World Health ◽  
Female Mortality ◽  
The Us ◽  
Male To Female

BackgroundThe lung is the most common site for cancer and has the highest worldwide cancer-related mortality. Our study reports and compares trends in lung cancer mortality in the United States (US) and 26 European countries.Study design and methodsLung cancer mortality data were extracted for males and females for each of the years 2000–2017 from the World Health Organization (WHO) Mortality and the Centers for Disease Control and Prevention (CDC) WONDER databases. Lung cancer mortality trends were compared using Joinpoint regression analysis, and male-to-female mortality ratios were calculated.ResultsDown-trending lung cancer mortality rates were observed in males in all countries except Cyprus and Portugal between 2000 and 2017. In females, increasing mortality rates were observed in 22 of the 27 countries analyzed. Latvia had the highest estimated annual percentage change (EAPC) in male mortality (−9.6%) between 2013–2015. In the US, EAPCs were −5.1% for males and −4.2% for females between 2014–2017. All countries had an overall decrease in the ratio of male-to-female lung cancer mortality. The most recent observation of median male-to-female mortality was 2.26 (IQR 1.92–4.05). The countries with the greatest current sex disparity in lung cancer mortality were Lithuania (5.51) and Latvia (5.00).ConclusionBetween 2000 and 2017, lung cancer mortality rates were decreasing for males in Europe and the US, whereas increasing lung cancer mortality rates were generally observed in females. There is a persistent but decreasing sex-mortality gap, with men having persistently greater lung cancer mortality but with rates decreasing faster than women.

scholarly journals 1788P Persistent sex-differences in lung cancer mortality between 2001 and 2017 in the US and EU

2020 ◽  
Vol 31 ◽  
pp. S1036-S1037
Author(s):  
C. Jani ◽  
D. Marshall ◽  
R. Goodall ◽  
H. Singh ◽  
J. Shalhoub ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Sex Differences ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The Us

Representation of minorities in randomized lung cancer trials in the United States.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e16517-e16517
Author(s):  
Mounika Mandadi ◽  
Goetz H. Kloecker
Keyword(s):  
Lung Cancer ◽  
African Americans ◽  
Cancer Mortality ◽  
Randomized Trials ◽  
Randomized Clinical Trials ◽  
Census Data ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Average Percentage ◽  
The Us

e16517 Background: The SEER data base shows a higher rate of lung cancer mortality for African Americans and a lower lung cancer mortality rate of Hispanics compared to Caucasians in the US. It is not clear if this is due to socioeconomic or biological factors. This study reviews the representation of Caucasians, African Americans (AA), Hispanics, and Asians in recent randomized trials published in the US. Methods: A systematic review was done of randomized trials in lung cancer published in the NEJM, JAMA, JCO. The percentage of patients of each race in the individual trials was listed. An average percentage with mean standard error for Caucasian, African-American, Hispanic and Asian race was obtained. The percentage for each group is compared to the racial distribution in the US Census data. Results: 30 randomized clinical trials were analyzed for racial distribution. A total of 227,411 patients were enrolled in the trials. Conclusions: African Americans and Hispanics have been significantly underrepresented in randomized trials published in the US. This affects the external validity of the trial results when generalizing the results to these minorities. Strategies to ensure accrual of people of all races are required to ameliorate the disparities clinical trial enrollment. [Table: see text]

Cancer as a Scottish Problem

1968 ◽  
Vol 13 (10) ◽  
pp. 338-348
Author(s):  
A. J. Haddow
Keyword(s):  
Breast Cancer ◽  
Lung Cancer ◽  
Cause Of Death ◽  
Cancer Mortality ◽  
Time Lag ◽  
Age Distribution ◽  
Lung Cancer Mortality ◽  
Cervix Uteri ◽  
Hospital Treatment ◽  
Cancer Of The Lung

Cancer, responsible for about 1 death in 5 in Scotland, cost over £1 per head of population in 1965 and led to bed occupation of almost 2,000 bed years. Time lag (symptoms-doctor-hospital-treatment) is usuallv small. Age distribution is as in other European countries. Excluding accidents, cancer is the second most important cause of death in children. In relation to other countries Scotland's position is very poor and the lung cancer mortality in both sexes is the highest known. Lung cancer is the most important in males, breast cancer in females. Alimentary cancers come second in both sexes. In this century alimentary cancers increased till the thirties or forties and then declined. Cancers of pancreas, cervix uteri, ovary, prostate, kidney and bladder, together with leukaemia, have all increased. Cancer of the lung has increased elevenfold in women and fiftyfold in men. It now accounts for 9 to 12 per cent of all male deaths in cities and large towns

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