The role of calcium and vitamin D dietary intake on risk of colorectal cancer: systematic review and meta-analysis of case–control studies

Author(s):  
Juan Francisco Lopez-Caleya ◽  
Luis Ortega-Valín ◽  
Tania Fernández-Villa ◽  
Miguel Delgado-Rodríguez ◽  
Vicente Martín-Sánchez ◽  
...  
2020 ◽  
Author(s):  
Juan Francisco Lopez-Caleya ◽  
Luis Ortega-Valín ◽  
Tania Fernández-Villa ◽  
Miguel Delgado-Rodríguez ◽  
Vicente Martín ◽  
...  

2020 ◽  
Vol 34 (5) ◽  
pp. 703-714
Author(s):  
Xiaoping Gao ◽  
Mei Yin ◽  
Pei Yang ◽  
Xia Li ◽  
Lingling Di ◽  
...  

Background Controversies persist regarding whether exposure to cat or dog increases the risk of asthma and allergic rhinitis. Objective This meta-analysis aimed to assess the associations between exposure to cats or dogs and the development of asthma and allergic rhinitis. Methods A systematic review was performed to identify case-control and cohort studies before May 2019, evaluating the association between exposure to cats and dogs and the risk of asthma and rhinitis. The risk of bias was assessed using the Newcastle–Ottawa Scale. The odds ratios (ORs) and risk ratios (RRs) were pooled for case-control and cohort studies, respectively. Subgroup analyses were performed on prespecified study-level characteristics. Results The meta-analysis of 34 cohort studies showed a protective role of exposure to cats [RR: 0.88, 95% confidence interval (CI): 0.77–0.99] or dogs (RR: 0.85, 95% CI: 0.73–0.97) in the development of asthma. The subgroup analysis of birth cohort (RR: 0.74, 95% CI: 0.56–0.93) and children population (RR: 0.83, 95% CI: 0.70–0.96) also suggested a favorable role of exposure to dogs in the development of asthma. Pooled evidence from 13 case-control studies indicated no significant impact of cats (OR: 1.66, 95% CI: 0.39–2.94) and dogs (OR: 1.22, 95% CI: 0.92–1.52) on the development of asthma. A pooled analysis of five cohort studies showed a favorable effect of exposure to cats (RR: 0.60, 95% CI: 0.33–0.86) or dogs (RR: 0.68, 95% CI 0.44–0.90) on the development of allergic rhinitis. Conclusion The findings indicated a protective effect of exposure to cats and dogs, especially ownership, on the development of asthma and allergic rhinitis.


Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2814
Author(s):  
Hatim Boughanem ◽  
Silvia Canudas ◽  
Pablo Hernandez-Alonso ◽  
Nerea Becerra-Tomás ◽  
Nancy Babio ◽  
...  

Obesity, a sedentary lifestyle, high red meat consumption and alcohol, and tobacco are considered the driving factors behind colorectal cancer (CRC) worldwide. Both diet and lifestyle are recognized to play an important role in the prevention of CRC. Forty years later, the vitamin D–cancer hypothesis is considered consistent. However, the relationship between low vitamin D intake and CRC is still controversial. The aim of this meta-analysis is to determine the associations between Vitamin D intake and CRC. MEDLINE-PubMed and Cochrane databases were searched up to May 2020 for studies evaluating the association between vitamin D intake (from foods and supplements) and CRC. Two reviewers, working independently, screened all titles and abstracts to identify the studies that met the inclusion criteria (case-control or prospective cohort (PC) studies published in English). Data were pooled by the generic inverse variance method using a random or fixed effect model. Heterogeneity was identified using the Cochran Q-test and quantified by the I2 statistic. A total of 31 original studies were included for the quantitative meta-analysis, comprising a total 47.540 cases and 70.567 controls in case-control studies, and a total of 14.676 CRC-incident cases (out of 808.130 subjects in PC studies) from 17 countries. A significant 25% lower risk was reported comparing the highest vs. the lowest dietary vitamin D consumption and CRC risk (odds ratio (95% confidence interval): 0.75 (0.67; 0.85)) in case-control studies, whereas a non-significant association was reported in case of prospective studies (hazard ratio (95% confidence interval): 0.94 (0.79; 1.11). The present meta-analysis demonstrates that high dietary vitamin D is associated to CRC prevention. However, larger and high-quality prospective studies and clinical trials are warranted to confirm this association.


Lung ◽  
2014 ◽  
Vol 192 (6) ◽  
pp. 955-965 ◽  
Author(s):  
Kalthoum Tizaoui ◽  
Anissa Berraies ◽  
Besma Hamdi ◽  
Wajih Kaabachi ◽  
Kamel Hamzaoui ◽  
...  

2018 ◽  
Vol 15 (3) ◽  
pp. 155 ◽  
Author(s):  
Rezvan Nasiri ◽  
Fatemeh Mashhadiabbas ◽  
Hossein Neamatzadeh ◽  
Elnaz Foroughi ◽  
Soudabeh Farahnak ◽  
...  

Author(s):  
Pablo Hernández-Alonso ◽  
Hatim Boughanem ◽  
Silvia Canudas ◽  
Nerea Becerra-Tomás ◽  
María Fernández de la Puente ◽  
...  

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