<p class="abstract"><strong>Background:</strong> The aim of this study was to determine the frequency of otomycosis, the clinical presentation, predisposing factors and treatment outcome.</p><p class="abstract"><strong>Methods:</strong> This observational study was conducted at ENT Department of Basaveshwara Medical College and Hospital, Research centre, Chitradurga from May 2018 to June 2019, 13 months study. There were 50 patients with documented diagnosis of otomycosis. There were 19 (38%) males and 31 (62%) females. The age of patients ranged from 3 years to 65 years with mean age of 32.5 years. Mean follow-up time was 1 year (~13 months). The frequency, predisposing factors and most common symptoms of otomycosis were recorded along with the response to different Antifungal agents were observed and results were recorded in percentages. Data were analysed using SPSS 12 software. Results are based on descriptive statistics. </p><p class="abstract"><strong>Results:</strong> We prescribed 1% clotrimazole drops or lotion in 58% of patients and 2% salicylic acid in 31% cases. Both of these agents are effective. Topical 1% clotrimazole drops yielded highest resolution rate with lowest recurrent rate. To analyse the efficacy of 1% clotrimazole and 2% salicylic acid. We applied Z-test to calculate the difference between two proportions of patients before treatment with those patients who remained uncured after treatment.</p><p class="abstract"><strong>Conclusions:</strong> Otomycosis commonly prevented with hearing loss, pruritus, otalgia and otorrhoea. It usually resolves with local toilet of ear and installation of antifungal agents.</p>