scholarly journals Bacteriological profile and drug sensitivity patterns in chronic suppurative otitis media patients at J. L. N. Hospital & Research Centre, Bhilai, Chhattisgarh State, India

Author(s):  
Rashmi Ramashesh ◽  
Samira Abdul Wajid ◽  
Smitha Chandra

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is an ever growing concern of preventable hearing loss and is a major health concern especially in tropical countries. Lack of cleanliness, overcrowding, poverty, malnutrition and medical ignorance are few of the contributing factors. The microbiological flora is constantly changing due to indiscriminate use of antibiotics with rapid change in the antibiotic sensitivity patterns. Hence, this study was undertaken to determine the epidemiological profile, bacteriological profile and the antibiotic sensitivity pattern which would help in establishing a protocol in management of CSOM patients in the hospital.</p><p class="abstract"><strong>Methods:</strong> A total of 100 patients of CSOM attending the ENT Outpatient Department of The Oxford medical College, Hospital and Research Centre were included in the study. The samples were immediately sent to the Microbiology laboratory for further processing according to standard procedure.  </p><p class="abstract"><strong>Results:</strong> Out of 100 cases, 74 were active mucosal type and 26 were active squamous, with Pseudomonas species (33.6%) being the predominant organism. <em>Staphylococcus aureus</em> was the next common organism with MSSA (16.3%) and MRSA (12.5%), CONS were 6.7%. Among the 28 gram-negative bacilli, <em>Klebsiella pneumoniae</em> (7.7%), was followed by <em>Escherichia coli</em> (5.7%), and <em>Proteus mirabilis</em> (4.8%).</p><p class="abstract"><strong>Conclusions:</strong> Pseudomonas species and <em>Staphylococcus aureus</em> are the commonest organisms of CSOM. Ciprofloxacin can be used as a topical agent for treating gram-negative bacilli. Among systemic antibiotics- Linezolid, Amikacin and Imepenam remains the drug of choice.</p><p><br /><br /></p>


2020 ◽  
pp. 1-4
Author(s):  
Ajit Damle

Introduction: Chronic suppurative otitis media (CSOM) is a destructive and persistent disease with irreversible sequel and can proceed to serious intra and / or extra cranial complications. Causative agents of infection include bacteria, fungi and viruses with bacteria being the commonest cause. Hence bacteriological studies of CSOM are important for determining effective antibiotic choice and surveillance of bacterial patterns and their relative sensitivities. Materials and Methods:Total 157 patients having CSOM were included in the study. Ear discharge was processed with standard Microbiological procedures. Results: On aerobic culture Staphylococcus aureus 58 (36.96%) was the most common isolate followed by Pseudomonas aeruginosa 35 (21.21%). Fungal culture yielded 19 (11.2%) isolates. Conclusion: Evaluation of microbiological pattern and antibiotic sensitivity of isolates is necessary to decrease the potential risk of complications of CSOM by early institution of appropriate treatment.


2006 ◽  
Vol 21 (1-2) ◽  
pp. 20-23 ◽  
Author(s):  
Patricia N. Ayson ◽  
Jan Eero G. Lopez ◽  
Erasmo Gonzalo DV. Llanes

Objectives: To identify the bacterial pathogens associated with chronic suppurative otitis media and their antimicrobial sensitivity and resistance   Study Design: Cross-sectional survey   Setting: The study was carried out from July 2004-July 2005 at the outpatient clinic of a government tertiary hospital.   Number of subjects: A total of 32 patients (54 ears) with unilateral or bilateral active chronic suppurative otitis media.   Results: Bacterial pathogens of 54 ear discharge samples from CSOM were studied. Among them, 42 (78%) were pure cultures and 9 (16.7%) were mixed, only 3 (5.6%) of the submitted samples had no growth. There were 42 pure isolates, the most common of which was Staphylococcus aureus 21 (50%), followed by Pseudomonas aeruginosa 14 (33.3%). Drug sensitivity pattern of Staphylococcus aureus showed that 61.9% were resistant to Penicillin while more than 90% were sensitive to Aminoglycosides and Clindamycin. Pseudomonas aeruginosa was resistant to penicillin in 64.3% of cases and Ciprofloxacin was active against pseudomonas in 85.7%.   Conclusion: The most common bacterial pathogens from CSOM include Staphylococcus aureus and Pseudomonas aeruginosa. Majority of the isolates of Staphylococcus aureus were resistant to penicillin. Aminoglycosides, macrolides and quinolones were effective against most of the isolates of Staphylococcus aureus.   Keywords: chronic otitis media, perforated tympanic membrane, chronic aural discharge    


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