Treatment outcome of creatine transporter deficiency: international retrospective cohort study

2018 ◽  
Vol 33 (3) ◽  
pp. 875-884 ◽  
Author(s):  
Theodora U. J. Bruun ◽  
Sarah Sidky ◽  
Anabela O. Bandeira ◽  
Francoise-Guillaume Debray ◽  
Can Ficicioglu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Treatment Outcome ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Creatine Transporter ◽  
Creatine Transporter Deficiency ◽  
Transporter Deficiency

Absolute Abstinence as a Treatment Outcome in Servicemen with Alcohol Dependence: A Retrospective Cohort Study

2019 ◽  
Vol 54 (14) ◽  
pp. 2304-2316 ◽  
Author(s):  
Ashutosh Ratnam ◽  
R. C. Das ◽  
T. Madhusudan ◽  
Pankaj Sharma ◽  
S. P. Panda
Keyword(s):  
Cohort Study ◽  
Treatment Outcome ◽  
Alcohol Dependence ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort

scholarly journals Exploration of turn-positive RT-PCR results and factors related to treatment outcome in COVID-19: A retrospective cohort study

Virulence ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 1250-1256
Author(s):  
Yong Xiao ◽  
Xiao Shi ◽  
Qian She ◽  
Qi Chen ◽  
Hong Pan ◽  
...  
Keyword(s):  
Cohort Study ◽  
Treatment Outcome ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Rt Pcr

scholarly journals 1342. Impact of HIV Infection on Treatment Outcome of New Tuberculosis Patients Attending Tuberculosis and Antiretroviral Treatment Services in the Community-Based Hospital, Thailand: A Retrospective Cohort Study

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S485-S486
Author(s):  
Subencha Pinsai
Keyword(s):  
Cohort Study ◽  
Treatment Outcome ◽  
Hiv Infection ◽  
Success Rate ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Treatment Success ◽  
Treatment Success Rate ◽  
Factors Associated ◽  
The Impact

Abstract Background Tuberculosis (TB) and HIV are one of the significant public health problems in Thailand, and an estimated 15,000 individuals have a dual infection. Both HIV and TB each disease speeds up the progression of each other. TB is the leading cause of death in HIV-infected individuals, and HIV coinfected TB patients have disease-specific, and treatment affected their treatment outcomes. There is insufficient evidence on issues of TB and HIV co-infection patients received treatment. This study aimed to assess the impact of HIV status on treatment outcome of TB patients. Methods We conducted a retrospective cohort study among TB patients who registered to service at Chaophraya Abhaibhubejhr Hospital, Prachin Buri, Thailand from October 1, 2017 to October 31, 2018. All patients’ demographic data, diagnosis, and treatment were retrieved. Clinical characteristics, treatment outcome, and factors associated with treatment outcome were analyzed. Results There were 49 (10.65%) HIV among 460 TB patients with a median (IQR) age of 44 (32–61) years old and 65.2% were males. Disseminated TB and extrapulmonary TB were higher in HIV coinfected group (P < 0.001). All pulmonary TB patients’ lower lobe involvement was higher in HIV coinfected group (62.50 vs. 36.00, P = 0.001). In HIV coinfected group median CD4 was 134 cell/mm3 (IQR 19–294), 66.67% were diagnosed HIV infection after TB diagnosis, the median time from TB diagnosed to antiretroviral was 29 days (IQR 21–48). The overall treatment success rate was 93.04%; the treatment success rate was similar in HIV coinfected TB patients (89.80%) and non- HIV-infected patients (93.43%) (P = 0.66).Adverse drug reactions were higher in HIV coinfected group (44.89% vs 12.41%) (P < 0.001). By multiple stepwise logistic regression, factors associated with anti-TB drug adverse reactions were having HIV infection (OR 7.99; 95% CI 3.73–17.10, P < 0.001), Age >60 years (OR 2.64; 95% CI 1.43–4.87, P = 0.002) and female sex (OR 1.97; 95% CI 1.11–3.52, P = 0.02). Conclusion There is a high TB treatment success rate among patients who have treated for TB, but adverse drug events in HIV co-infected TB patients is higher than that observed in non-HIV-infected patients. Disclosures All authors: No reported disclosures.

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