Exploration of immunomodulatory and protective effect of Withania somnifera on trace metal oxide (zinc oxide nanoparticles) induced toxicity in Balb/c mice

2019 ◽  
Vol 46 (2) ◽  
pp. 2447-2459 ◽  
Author(s):  
Jitendra Kumar ◽  
Murli Dhar Mitra ◽  
Ahmad Hussain ◽  
Gautam Kaul
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Trace Metal ◽  
Protective Effect ◽  
Zinc Oxide Nanoparticles ◽  
Withania Somnifera ◽  
Oxide Nanoparticles

scholarly journals Utility of Zinc Oxide Nanoparticles Catalytic Activity in the Electrochemical Determination of Minocycline Hydrochloride

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2505
Author(s):  
Amal M. Al-Mohaimeed ◽  
Wedad A. Al-Onazi ◽  
Maha F. El-Tohamy
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Electrochemical Determination ◽  
Electrochemical Sensing ◽  
Oxide Nanoparticles ◽  
Regression Equations ◽  
Minocycline Hydrochloride

The current work described the synthesis and characterization of zinc oxide nanoparticles (ZnONPs) and their electrocatalytic activity in the determination of minocycline hydrochloride (MCL). The unique features of metal oxide nanoparticles such as zinc oxide encourage the researchers to investigate the activity of metal oxide nanoparticles as remarkable semiconductor materials active in the electrochemical sensing determination. Herein, the suggested study displayed a comparative determination of minocycline hydrochloride using two conventional and modified ZnONPs-coated wire sensors. The recorded results showed the linear behavior of the enriched ZnONPs sensor over the 1.0 × 10−10–1.0 × 10−2 mol L−1 with respect to 1.0 × 10−6–1.0 × 10−2 mol L−1 for the conventional sensor. The two sensors are working in the pH range of 3–5 with regression equations EmV = (53.2 ± 0.5) log [MCL] + 448.8 and EmV = (58.7 ± 0.2) log [MCL] + 617.76 for conventional and enriched ZnONPs, respectively. The correlation coefficients were 0.9995 and 0.9998 for the previously mentioned sensors, respectively. The validity of the suggested analytical method was evaluated according to the recommended guidelines for methodology and drug analysis. The developed sensors were also used in the quantification of MCL in commercial formulations.

Preparation of zinc oxide nanoparticles using punica granatum and elettaria cardamomum fruit extract and determining its antibacterial activity against lactobacillus

2020 ◽  
Vol 11 (3) ◽  
pp. 3372-3376
Author(s):  
Shilpa Merlyn Jose ◽  
Hannah.R ◽  
Rajeshkumar S
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Punica Granatum ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Fruit Extract ◽  
Elettaria Cardamomum

To determine the antibacterial activity of Zinc oxide nanoparticles synthesised using Punica granatum and Elettaria cardamomum fruit extract against Lactobacillus. Punica granatum and Elettaria cardamomum have been known for their antimicrobial, antioxidant and anti-inflammatory activity. The phytochemicals present in these fruits have experimented for the preparation of various metal and metal oxide nanoparticles. Zinc oxide is a widely used metal oxide nanoparticle known for its good antimicrobial activity against a host of microbes. The current study was conducted to determine its effect against Lactobacillus, a bacteria known for its role in the progression of dental caries. Preparation of fruit extract mediated zinc oxide nanoparticles. Determining the characteristics of the nanoparticles using UV spectroscopy and SEM. Analysing the activity of these nanoparticles against Lactobacillus using agar well diffusion method. The zone of inhibition increased if the concentration of the fruit mediated zinc oxide nanoparticles increased. But it was incomparable to the standards. Hence, further studies need to be conducted using different concentration of Punica granatum and Elettaria cardamomum to determine the optimum fruit extract required for the preparation of the nanoparticles. The resultant nanoparticles can be used as an effective antimicrobial agent against Lactobacillus

Protective effect of the NAC and Sal on zinc oxide nanoparticles-induced reproductive and development toxicity in pregnant mice

2020 ◽  
Vol 143 ◽  
pp. 111552 ◽  
Author(s):  
Bolu Chen ◽  
Wuding Hong ◽  
Yizhou Tang ◽  
Yu Zhao ◽  
Zoraida P. Aguilar ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Protective Effect ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Pregnant Mice

scholarly journals Protective Effect of Fruit Juices on Zn Nanoparticles Induced Toxicity

2020 ◽  
Vol 2 (1) ◽  
pp. 54
Keyword(s):  
Zinc Oxide ◽  
Protective Effect ◽  
Zinc Oxide Nanoparticles ◽  
Seedling Emergence ◽  
Chemical Properties ◽  
Fruit Juices ◽  
Oxide Nanoparticles ◽  
Zno Nanoparticle ◽  
Cytotoxicity Studies ◽  
Vis Spectroscopy

Nanotoxicology refers to the study of the interaction of nanostructure with a biological system with an emphasis on elucidating the relationship between the physical and chemical properties of nanostructure with the induction of toxic biological responses. In this study, an attempt has been made to understand the protective effect of fruit juices on the reduction of ZnO nanoparticle-induced toxicity. Zinc oxide nanoparticles were synthesized by chemical reaction of zinc nitrate with sodium hydroxide as the reducer. Synthesized nanoparticles were characterized by suitable analytical techniques. UV-Vis spectroscopy study reveals the Plasmon absorption maxima at 200-600 nm, and X-ray diffraction and Atomic Force Microscopic analyses revealed the highly stable nanoparticles. Nanoparticles coated fruit juices was confirmed by changes or shift in the absorption spectra. Phytotoxicity studies indicated that the fruit juices coated zinc oxide nanoparticles were not inducing any effect on seedling emergence and plant growth. Cytotoxicity studies using RAW 264.7 cell lines were done by MTT Assay, where the IC50 values.

scholarly journals Protective effect of zinc oxide nanoparticles on sperm parameters after freezing

2020 ◽  
Vol 5 (1) ◽  
pp. 10-17
Author(s):  
Elnaz Ashtari ◽  
Fatemeh Siadat ◽  
Niloofar Sodeifi ◽  
Sajjad Atashparvar ◽  
◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Protective Effect ◽  
Zinc Oxide Nanoparticles ◽  
Sperm Parameters ◽  
Oxide Nanoparticles

scholarly journals Nano ZnO and its Perspective in Anti-Cancer Activities

2017 ◽  
Vol 16 (2) ◽  
pp. 41-52
Author(s):  
N Shobhaa ◽  
N Nandab ◽  
B M Nagabhushana
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Nano Particles ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Large Bandwidth ◽  
Anti Cancer ◽  
Potential Applications

Several methods are used to counter the deadly disease cancer. Zinc oxide nanoparticles (ZnO NPs) is one of the metal oxide nanoparticles which had been used in anti-cancer activities due to its large bandwidth and high exciting binding energy and it has potential applications like antibacterial, antifungal, anti-diabetic, anti-inflammatory, wound healing, antioxidant, optic properties and also which holds promise to treat cancer effectively. Studies have shown that Zinc metal oxide nano particles induce cytotoxicity in cancer cells. The mechanism for antitumor could work through apoptosis or the generation of reactive oxygen species or and necrosis, among other possibilities. This review is on some of the most significant antitumor results obtained with zinc oxide nanoparticles depending on their size, surface morphology, methods of preparation and also cytotoxicity result.

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