Effect of Cold Atmospheric Plasma Jet and Gamma Radiation Treatments on Gingivobuccal Squamous Cell Carcinoma and Breast Adenocarcinoma Cells

2021 ◽  
Author(s):  
Kshama Pansare ◽  
Akshay Vaid ◽  
Saurav Raj Singh ◽  
Ramkrishna Rane ◽  
Anand Visani ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Gamma Radiation ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Plasma Jet ◽  
Atmospheric Plasma ◽  
Breast Adenocarcinoma ◽  
Cold Atmospheric Plasma ◽  
Adenocarcinoma Cells ◽  
Radiation Treatments

scholarly journals Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells

2014 ◽  
Vol 34 (4) ◽  
pp. 941-946 ◽  
Author(s):  
RAFAEL GUERRERO-PRESTON ◽  
TAKENORI OGAWA ◽  
MAMORU UEMURA ◽  
GARY SHUMULINSKY ◽  
BLANCA L. VALLE ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Plasma Treatment ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Carcinoma Cells ◽  
Neck Squamous Cell Carcinoma ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma

scholarly journals Metaplastic squamous cell carcinoma of the breast: A case report and literature review

2016 ◽  
Vol 62 (7) ◽  
pp. 618-621 ◽  
Author(s):  
Luciana Graziano ◽  
Paschoal Graziano Filho ◽  
Almir Galvão Vieira Bitencourt ◽  
Daniel Bernal Soto ◽  
Alexandre Hiro ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Course ◽  
Squamous Cell Carcinomas ◽  
Metaplastic Carcinoma ◽  
Breast Adenocarcinoma ◽  
Imaging Studies ◽  
Carcinoma Of The Breast ◽  
Average Size

Summary Metaplastic tumors are rare and represent a heterogeneous group of neoplasms showing dominant areas of non-glandular differentiation. Etiology and pathogenesis of this type of lesion in the breast is uncertain. The most common sources of metastatic squamous cell carcinoma of the breast are lung, esophagus, cervix, and urinary bladder. Squamous cell carcinomas may present clinically with inflammation and average size greater than breast adenocarcinoma. As for imaging studies, mammography shows no typical findings and ultrasound can show a complicated cyst or an inflammatory process, among the differential diagnoses. Therefore, knowing this pathological entity, its clinical course and imaging findings is important to safely treat such a rare and aggressive disease. We herein report a case of metaplastic carcinoma, squamous subtype, diagnosed by core needle biopsy.

ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways

2014 ◽  
Vol 92 (11) ◽  
pp. 1209-1223 ◽  
Author(s):  
Christiane D. Fichter ◽  
Verena Gudernatsch ◽  
Camilla M. Przypadlo ◽  
Marie Follo ◽  
Gudula Schmidt ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Migration ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Signaling Pathways ◽  
Squamous Cell ◽  
Adenocarcinoma Cells

scholarly journals The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells

Oncotarget ◽  
2015 ◽  
Vol 6 (34) ◽  
pp. 35652-35666 ◽  
Author(s):  
Diana Spiegelberg ◽  
Adrian Dascalu ◽  
Anja C. Mortensen ◽  
Andris Abramenkovs ◽  
Gamze Kuku ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Radiation Effects ◽  
Hsp90 Inhibitor ◽  
The Novel ◽  
Adenocarcinoma Cells

scholarly journals PIK3C2Bpromotes epithelial to mesenchymal transition and EGFR inhibitors insensitivity in epidermal squamous cell carcinoma

2018 ◽  
Author(s):  
Silvia Crespo Pomar ◽  
Anna Borgström ◽  
Alexandre Arcaro ◽  
Roch-Philippe Charles
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epithelial To Mesenchymal Transition ◽  
Colon Adenocarcinoma ◽  
A431 Cells ◽  
Mesenchymal Transition ◽  
Adenocarcinoma Cells ◽  
E Cadherin

AbstractWhile the class I of PI3Ks has been deeply studied due to its clear implication in cancer development, little is known about the class II of PI3Ks. However, recent accumulation of data is now revealing that PI3KC2β, one isoform of this class of PI3Ks, may also play a role in cancer. Specifically, recent studies have suggested an implication of PI3KC2β in metastasis formation through the promotion of epithelial to mesenchymal transition (EMT). Here, we report that the overexpression of PI3KC2β in the epidermal squamous cell carcinoma (ESCC) cells A431 promotes apparent EMT transformation. We further confirm this EMT by showing modification in several biochemical markers (E-cadherin, β-catenin, Snail, Twist1 and Vimentin). Furthermore, an intracellular co-localization of E-cadherin, β-catenin and EGFR was observed. This transformation decreased EGFR signaling and the sensitivity to inhibitors targeting this receptor. To confirm our results, we have used the colon adenocarcinoma cells HT29 and induced overexpression of PI3KC2β in these cells. We could recapitulate in this model some of our major findings regarding EMT in the PI3KC2β overexpressing A431 cells. Taken together, these data support a role of PI3KC2β in promoting EMT.

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