Bleaching earth clay pH 12.5/PEG-400 catalytic system for synthesis of some novel α, β-unsaturated ketones (chalcones)

2014 ◽  
Vol 41 (7) ◽  
pp. 4673-4678 ◽  
Author(s):  
Milind V. Gaikwad ◽  
Rahul D. Kamble ◽  
Shrikant V. Hese ◽  
Ashok P. Acharya ◽  
Pratima P. Mogle ◽  
...  
Keyword(s):  
Catalytic System ◽  
Bleaching Earth ◽  
Unsaturated Ketones ◽  
Peg 400

scholarly journals Synthesis and Antioxidant Evaluation of Indole Quinoline Derived Chalcones

2021 ◽  
Vol 34 (1) ◽  
pp. 235-238
Author(s):  
Pranita V. Raithak ◽  
Arvind S. Dhabe ◽  
Sandeep T. Atkore ◽  
M. Mujahid Alam ◽  
Vijay Kotra ◽  
...  
Keyword(s):  
Ambient Temperature ◽  
Spectral Data ◽  
Catalytic System ◽  
Bleaching Earth ◽  
Cost Effective ◽  
Peg 400 ◽  
Antioxidant Evaluation

A series of novel indole quinoline derived chalcones were synthesized using cost-effective synergetic catalytic system consisting of heterogeneous basic bleaching earth clay (pH 12.5) and PEG-400 as solvent at ambient temperature with the yields of 60-76%. All these chalcones were characterized by spectral data. Both the DPPH and SOR scavenging assays were performed to evaluate their antioxidant nature of these compounds.

“Green synthesis” of benzothiazepine library of indeno analogues and their in vitro antimicrobial activity

2014 ◽  
Vol 68 (5) ◽  
Author(s):  
Ashok Acharya ◽  
Rahul Kamble ◽  
Snehalkumar Patil ◽  
Shrikant Hese ◽  
Omprakash Yemul ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Acetic Acid ◽  
Ethylene Glycol ◽  
Bleaching Earth ◽  
Poly Ethylene Glycol ◽  
Unsaturated Ketones ◽  
Peg 400 ◽  
Green Route ◽  
Poly Ethylene

AbstractA novel series of indeno-benzothiazepine derivatives was synthesised via a “green” route. Synthesis of these compounds involves the treatment of dinucleophiles such as 2-aminobenzenethiols with α,β-unsaturated ketones in poly(oxyethylene) (poly(ethylene glycol), PEG-400) catalysed by acetic acid. The synthone α,β-unsaturated ketones were obtained by Claisen-Schmidt condensation of indan-1-one with substituted pyrazole-2-carbaldehydes prompted by bleaching earth (pH 12.5) as catalyst and PEG-400 as “green” reaction solvent. Screening of all the synthesised compounds for antimicrobial activity revealed that most of these compounds exhibited moderate to significant antimicrobial activity.

Bleaching earth clay (pH 12.5)/PEG-400: an efficient recyclable catalytic system for synthesis of 5,6,7,8-tetrahydroquinoline-3-carbonitrile derivatives

2014 ◽  
Vol 41 (10) ◽  
pp. 7541-7551 ◽  
Author(s):  
Pratima P. Mogle ◽  
Rahul D. Kamble ◽  
Shrikant V. Hese ◽  
Bhaskar S. Dawane
Keyword(s):  
Catalytic System ◽  
Bleaching Earth ◽  
Peg 400

scholarly journals Synthesis of 14-Substituted-14H-Dibenzo[a,j]Xanthene Derivatives in Presence of Effective Synergetic Catalytic System Bleaching Earth Clay and PEG-600

Catalysts ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1294
Author(s):  
Sandeep T. Atkore ◽  
Giribala M. Bondle ◽  
Pranita V. Raithak ◽  
Vinod T. Kamble ◽  
Ravi Varala ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Catalytic System ◽  
Present Method ◽  
Condensation Reaction ◽  
Bleaching Earth ◽  
Product Yield ◽  
Xanthene Derivatives ◽  
Peg 600

The synthesis of 14-aryl 14H-dibenzo[a,j]xanthenes is achieved by a simple condensation reaction between β-naphthol with aryl or alkyl aldehydes in an effective synergetic catalytic system created by combining basic bleaching earth clay and PEG-600. The advantages of the present method include catalyst recyclability, superior product yield, a shorter reaction time and the avoidance of hazardous reagents. Synthesized xanthene derivatives were also screened for their antibacterial activity against Staphylococcus aureus (MTCC 96) and Pseudomonas aeruginosa (Wild).

scholarly journals Microwave-Assisted Synthesis of Tetrahydrocarbazole Linked 1,2-Diazoles in Aqueous-Brønsted Acid Catalytic System

2017 ◽  
Vol 2017 ◽  
pp. 1-17 ◽  
Author(s):  
Zubi Sadiq ◽  
Erum Akbar Hussain ◽  
Narjis Naz ◽  
Ambreen Ghani ◽  
Kausar Yasmeen ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Catalytic System ◽  
Multicomponent Reaction ◽  
Conventional Heating ◽  
Microwave Assisted Synthesis ◽  
Spectroscopic Techniques ◽  
Unsaturated Ketones ◽  
Microwave Assisted ◽  
Michael Type Addition

A new series of tetrahydrocarbazole coupled 1,2-diazoles 4/5/6(a–o) in moderate to excellent yield was synthesized successfully via multicomponent reaction approach by adopting Michael type-addition of hydrazines on in situ generated α,β-unsaturated ketones via aldol type strategy under synthetic microwave radiations and conventional heating. Structural confirmations of all the prepared compounds were achieved by spectroscopic techniques. The best results were achieved when equal amounts of water-acetic acid were used in microwave conditions in 4 minutes.

scholarly journals Combination of RuCl3·xH2O with PEG – a simple and recyclable catalytic system for direct arylation of heteroarenes via C–H bond activation

RSC Advances ◽  
2017 ◽  
Vol 7 (38) ◽  
pp. 23515-23522 ◽  
Author(s):  
Lei Jian ◽  
Hai-Yu He ◽  
Jin Huang ◽  
Qian-Hui Wu ◽  
Mao-Lin Yuan ◽  
...  
Keyword(s):  
Catalytic System ◽  
Bond Activation ◽  
Direct Arylation ◽  
Peg 400

A simple and recyclable catalytic system for direct arylation of heteroarenes via C–H bond activation was developed with a relatively inexpensive RuCl3·xH2O as a catalyst and PEG-400 as a green medium without any additive or ligand.

N-Tosylhydrazone directed annulation via C–H/N–N bond activation in Ru(ii)/PEG-400 as homogeneous recyclable catalytic system: a green synthesis of isoquinolines

2018 ◽  
Vol 16 (26) ◽  
pp. 4864-4873 ◽  
Author(s):  
Dewal S. Deshmukh ◽  
Bhalchandra M. Bhanage
Keyword(s):  
Green Synthesis ◽  
Catalytic System ◽  
Bond Activation ◽  
Peg 400 ◽  
System A ◽  
Directing Group

A green and sustainable methodology for the synthesis of isoquinolines using Ru(ii)/PEG-400 as homogeneous recyclable catalytic system and N-tosylhydrazone, a rarely explored directing group has been reported.

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