Prevalence and molecular epidemiology of equine piroplasmosis in China: a neglected tick-borne disease

Author(s):  
Kewei Chen ◽  
Zhe Hu ◽  
Jingkun Li ◽  
Jingfei Wang ◽  
Diqiu Liu ◽  
...  
Author(s):  
ThankGod E. Onyiche ◽  
Keisuke Suganuma ◽  
Ikuo Igarashi ◽  
Naoaki Yokoyama ◽  
Xuenan Xuan ◽  
...  

Equine Piroplasmosis (EP) is a tick-borne disease caused by apicomplexan protozoan parasites, Babesia caballi and Theileria equi. The disease is responsible for serious economic losses to the equine industry. It principally affects donkeys, horses, mules, and zebra but DNA of the parasites has also been detected in dogs and camels raising doubt about their host specificity. The disease is endemic in tropical and temperate regions of the world where the competent tick vectors are prevalent. Infected equids remain carrier for life with T. equi infection, whilst, infection with B. caballi is cleared within a few years. This review focuses on all aspects of the disease from the historical overview, biology of the parasite, epidemiology of the disease (specifically highlighting other non-equine hosts, such as dogs and camels), vector, clinical manifestations, risk factors, immunology, genetic diversity, diagnosis, treatment, and prevention.


Pathogens ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 926
Author(s):  
Sharon Tirosh-Levy ◽  
Yuval Gottlieb ◽  
Lindsay M. Fry ◽  
Donald P. Knowles ◽  
Amir Steinman

Equine piroplasmosis (EP), caused by the hemoparasites Theileria equi, Theileria haneyi, and Babesia caballi, is an important tick-borne disease of equines that is prevalent in most parts of the world. Infection may affect animal welfare and has economic impacts related to limitations in horse transport between endemic and non-endemic regions, reduced performance of sport horses and treatment costs. Here, we analyzed the epidemiological, serological, and molecular diagnostic data published in the last 20 years, and all DNA sequences submitted to GenBank database, to describe the current global prevalence of these parasites. We demonstrate that EP is endemic in most parts of the world, and that it is spreading into more temperate climates. We emphasize the importance of using DNA sequencing and genotyping to monitor the spread of parasites, and point to the necessity of further studies to improve genotypic characterization of newly recognized parasite species and strains, and their linkage to virulence.


2016 ◽  
Vol 61 (2) ◽  
Author(s):  
Darko Davitkov ◽  
Milos Vucicevic ◽  
Jevrosima Stevanovic ◽  
Vanja Krstic ◽  
Dajana Slijepcevic ◽  
...  

AbstractEquine piroplasmosis is significant tick-borne disease with wide distribution. The prevalence of equine piroplasmosis in Serbia, Montenegro and Bosnia and Herzegovina is unknown. In aim to obtain a first insight into the prevalence we performed molecular epidemiological study which included 142 horses, on seven locations in these three countries. We first performed PCR for the detection of a 450bp long section of the 18S rRNA of piroplasma-specific region. For all positive samples we have done multiplex PCR for the species detection. Species determination was further confirmed by sequencing PCR products of 10 randomly selected


2017 ◽  
Vol 62 (1) ◽  
Author(s):  
Esin Guven ◽  
Hamza Avcioglu ◽  
Ahmet Deniz ◽  
İbrahim Balkaya ◽  
Ugur Abay ◽  
...  

AbstractEquine piroplasmosis (EP) is a hemoprotozoan tick-borne disease with worldwide distribution that is caused by


2019 ◽  
Vol 75 (02) ◽  
pp. 6230-2019
Author(s):  
LORA KOENHEMSİ ◽  
FATMA ATEŞ ALKAN ◽  
GİULİA MORGANTİ ◽  
BORA Ü. BARUTÇU ◽  
ERMAN M. OR

Equine piroplasmosis (EP) is a tick-borne disease caused by Babesia caballi and Theileria equi, which causes a significant economic loss. The aim of this study was to determine the disease-related changes of serum trace elements that play an important role in the immune system. Our study was conducted on 20 horses with piroplasmosis and 20 healthy horses. It was performed to evaluate some of the serum trace element levels (chromium (Cr), copper (Cu), iron (Fe), magnesium (Mg) manganese (Mn), selenium (Se), zinc (Zn), arsenic (As), boron (B), and nickel (Ni)) in equine piroplasmosis. The elements were analyzed in serum using ICP-OES. Infected horses had significantly higher serum Mg and Mn levels. In conclusion, changes of serum trace elements in infected horses can provide valuable information about pathophysiological aspects and they are also good indicators for diagnosis, prognosis and treatment evaluation. Much more scientific research is required to evaluate the trace elements related to equine piroplasmosis.


Pathology ◽  
2009 ◽  
pp. 1-5
Author(s):  
Tse Koh ◽  
Beng Low ◽  
Nicholas Leo ◽  
Li-Yang Hsu ◽  
Raymond Lin ◽  
...  

2011 ◽  
Vol 152 (16) ◽  
pp. 633-641 ◽  
Author(s):  
Katalin Gőcze ◽  
Katalin Gombos ◽  
Gábor Pajkos ◽  
Ingrid Magda ◽  
Ágoston Ember ◽  
...  

Cancer research concerning short non-coding RNA sequences and functionally linked to RNA interference (RNAi) have reached explosive breakthrough in the past decade. Molecular technology applies microRNA in extremely wide spectrum from molecular tumor prediction, diagnostics, progression monitoring and prevention. Functional analysis of tissue miRNA and cell-free serum miRNA in posttranscription and translation regulation innovated and restructured the knowledge on the field. This review focuses on molecular epidemiology and primary prevention aspects of the small non-coding RNA sequences. Orv. Hetil., 2011, 152, 633–641.


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