Numerical investigation of patient-specific thoracic aortic aneurysms and comparison with normal subject via computational fluid dynamics (CFD)

2020 ◽  
Author(s):  
Mustafa Etli ◽  
Gokhan Canbolat ◽  
Oguz Karahan ◽  
Murat Koru
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Numerical Investigation ◽  
Aortic Aneurysms ◽  
Patient Specific ◽  
Thoracic Aortic Aneurysms ◽  
Normal Subject ◽  
Computational Fluid Dynamics Cfd

scholarly journals Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth

2021 ◽  
Vol 11 (4) ◽  
pp. 520
Author(s):  
Emily R. Nordahl ◽  
Susheil Uthamaraj ◽  
Kendall D. Dennis ◽  
Alena Sejkorová ◽  
Aleš Hejčl ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Kinetic Energy ◽  
Swirling Flow ◽  
Morphological Changes ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Aneurysm Wall ◽  
Aneurysm Growth ◽  
Computational Fluid Dynamics Cfd

Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume.

Manufacturing and Computational Fluid Dynamics Modeling of a Patient-Specific Fistula Model

2017 ◽  
Author(s):  
Yang Liu ◽  
Yihao Zheng ◽  
John Pitre ◽  
William Weitzel ◽  
Joseph Bull ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Patient Specific ◽  
Cfd Model ◽  
Dynamics Modeling ◽  
Computational Fluid Dynamics Modeling ◽  
Computational Fluid Dynamics Cfd ◽  
Particle Imaging ◽  
Venous Wall ◽  
Good Agreement

Arteriovenous fistula is the joining of an artery to a vein to create vascular access for dialysis. The failure or maturation of fistula is affected by the vessel wall shear stress (WSS), which is difficult to measure in clinic. A computational fluid dynamics (CFD) model was built to estimate WSS of a patient-specific fistula model. To validate this model, a silicone phantom was manufactured and used to carry out a particle imaging velocimetry (PIV) experiment. The flow field from the PIV experiment shows a good agreement with the CFD model. From the CFD model, the highest WSS (40 Pa) happens near the anastomosis. WSS in the vein is larger than that in the artery. WSS on the outer venous wall is larger than that on the inner wall. The combined technique of additive manufacturing, silicone molding, and CFD is an effective tool to understand the maturation mechanism of a fistula.

Experimental and Numerical Investigation of a Centrifugal Nozzle

2007 ◽  
Author(s):  
Jason Smith ◽  
Robert N. Eli
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Particulate Matter ◽  
Laboratory Experiment ◽  
Numerical Investigation ◽  
Industrial Applications ◽  
Fluid Mixing ◽  
Cfd Models ◽  
Computational Fluid Dynamics Cfd

This paper reports on a laboratory experiment conducted more than 30 years ago (Eli, 1974, unpublished), and recent Computational Fluid Dynamics (CFD) investigations, focusing on the properties of a plane tangential jet produced by an apparatus called a “centrifugal nozzle.” The authors believe that the centrifugal nozzle has potential industrial applications in several areas related to fluid mixing and particulate matter suspension in mixing tanks. It is also believed that this experiment, or one similar, may provide data useful for benchmarking CFD models.

scholarly journals Computational Fluid Dynamics for Cerebral Aneurysms in Clinical Settings

2021 ◽  
pp. 27-32
Author(s):  
Fujimaro Ishida ◽  
Masanori Tsuji ◽  
Satoru Tanioka ◽  
Katsuhiro Tanaka ◽  
Shinichi Yoshimura ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Clinical Settings ◽  
Geometry Model ◽  
Aneurysm Wall ◽  
3D Ct Angiography ◽  
Specific Geometry ◽  
Computational Fluid Dynamics Cfd

AbstractHemodynamics is thought to play an important role in the pathogenesis of cerebral aneurysms and recent development of computer technology makes it possible to simulate blood flow using high-resolution 3D images within several hours. A lot of studies of computational fluid dynamics (CFD) for cerebral aneurysms were reported; therefore, application of CFD for cerebral aneurysms in clinical settings is reviewed in this article.CFD for cerebral aneurysms using a patient-specific geometry model was first reported in 2003 and it has been revealing that hemodynamics brings a certain contribution to understanding aneurysm pathology, including initiation, growth and rupture. Based on the knowledge of the state-of-the-art techniques, this review treats the decision-making process for using CFD in several clinical settings. We introduce our CFD procedure using digital imaging and communication in medicine (DICOM) datasets of 3D CT angiography or 3D rotational angiography. In addition, we review rupture status, hyperplastic remodeling of aneurysm wall, and recurrence of coiled aneurysms using the hemodynamic parameters such as wall shear stress (WSS), oscillatory shear index (OSI), aneurysmal inflow rate coefficient (AIRC), and residual flow volume (RFV).

Simulating Coil Embolization Treatments of Intracranial Aneurysms Using Computational Fluid Dynamics

2019 ◽  
Author(s):  
Nikhil Tulshibagwale ◽  
Stephen P. Gent
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Coil Embolization ◽  
Fluid Velocity ◽  
Volume Flow ◽  
Patient Specific ◽  
Test Cases ◽  
Aneurysm Neck ◽  
Test Models ◽  
Computational Fluid Dynamics Cfd

In this study, a commercially available computational fluid dynamics (CFD) program was used to simulate coil embolization techniques, standard coiling (SC) and stent-assisted coiling (SAC), in simplified vessels that are representative of vessels found in the brain. The test models included a curved vessel, ranging from 3mm to 4mm in diameter. The vessel was afflicted with a spherical aneurysm, ranging from 8mm to 16mm in diameter. The four test cases were simulated without treatment, with SC treatment, and with SAC treatment, for a total of twelve simulations. The parameters of interest were blood volume flow into aneurysm, fluid velocity, wall shear stress (WSS), and vorticity. Results of the simulations indicate, on average, SC and SAC reduced volume flow into the aneurysm by 50% and to over 60%, respectively. Both SC and SAC appeared to reduce distal neck WSS. Both treatments reduced average overall dome WSS by approximately 76%. Average aneurysm neck velocity was reduced by both treatments; SC reduced neck velocity by 69% and SAC reduced neck velocity by 75%. Information on SC and SAC efficacy in idealized scenarios could assist medical professionals determining viable approaches for patient-specific cases and lays foundation for future CFD studies exploring coil embolization treatments.

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