scholarly journals Diagnostic Testing for SARS-CoV-2 Infection

Author(s):  
Emmanuel Thomas ◽  
Stephanie Delabat ◽  
David M. Andrews

Abstract Purpose of Review Given the rapid development of diagnostic approaches to test for and diagnose infection with SARS-CoV-2, many options are available to assess infection. Multiple established diagnostic companies are now providing testing platforms whereas initially, testing was being performed with simple PCR-based tests using standard laboratory reagents. Recent Findings. Additional testing platforms continue to be developed but challenges with testing, including obtaining testing reagents and other related supplies, are frequently encountered. With time, the testing supply chain will improve and more companies will be providing materials to support these testing efforts. In the USA, the need for rapid assay development and subsequent approval through attainment of emergency use authorization (EUA) has superseded the traditional arduous diagnostic testing approval workflow mandated by the FDA. It is anticipated that the USA will be able to continue to significantly increase its testing capabilities to address this pandemic; however, challenges remain due to the diversity of the performance characteristics of tests being utilized. Summary This review provides an overview of the current diagnostic testing landscape, with pertinent information related to SARS-CoV-2 virology and antibody responses, that is available to diagnose infection.

Viruses ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2492
Author(s):  
Emmanuel Thomas ◽  
Stephanie Delabat ◽  
Yamina L. Carattini ◽  
David M. Andrews

Purpose of Review Given the rapid development of diagnostic approaches to test for and diagnose infection with SARS-CoV-2 and its associated variants including Omicron (B.1.1.529), many options are available to diagnose infection. Multiple established diagnostic companies are now providing testing platforms whereas initially, testing was being performed with simple PCR-based tests using standard laboratory reagents. Recent Findings Additional testing platforms continue to be developed, including those to detect specific variants, but challenges with testing, including obtaining testing reagents and other related supplies, are frequently encountered. With time, the testing supply chain has improved, and more established companies are providing materials to support these testing efforts. In the United States (U.S.), the need for rapid assay development and subsequent approval through the attainment of emergency use authorization (EUA) has superseded the traditional arduous diagnostic testing approval workflow mandated by the FDA. Through these efforts, the U.S. has been able to continue to significantly increase its testing capabilities to address this pandemic; however, challenges still remain due to the diversity of the performance characteristics of tests being utilized and newly discovered viral variants. Summary This review provides an overview of the current diagnostic testing landscape, with pertinent information related to SARS-CoV-2 virology, variants and antibody responses that are available to diagnose infection in the U.S.


Author(s):  
Peng Li ◽  
Di Wu

The rapid development of e-commerce technologies has encouraged collection centers to adopt online recycling channels in addition to their existing traditional (offline) recycling channels, such the idea of coexisting traditional and online recycling channels evolved a new concept of a dual-channel reverse supply chain (DRSC). The adoption of DRSC will make the system lose stability and fall into the trap of complexity. Further the consumer-related factors, such as consumer preference, service level, have also severely affected the system efficiency of DRSC. Therefore, it is necessary to help DRSCs to design their networks for maintaining competitiveness and profitability. This paper focuses on the issues of quantitative modelling for the network design of a general multi-echelon, dual-objective DRSC system. By incorporating consumer preference for the online recycling channel into the system, we investigate a mixed integer linear programming (MILP) model to design the DRSC network with uncertainty and the model is solved using the ε-constraint method to derive optimal Pareto solutions. Numerical results show that there exist positive correlations between consumer preference and total collective quantity, online recycling price and the system profits. The proposed model and solution method could assist recyclers in pricing and service decisions to achieve a balance solution for economic and environmental sustainability.


2021 ◽  
Vol 37 (3) ◽  
pp. 34-35

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings This research paper concentrates on the capacity of procurement digitalization to pump up supply chain effectiveness and competitive advantage levels. Data from the examination of the strategic actions of an environmental charity, an IT multinational, and an Australian SME reveal that increasing procurement effectiveness translates into marked performance enhancements in terms of productivity gains and reduced costs. Wiping away boundaries between buyers and suppliers produced procurement processes with greater scalability, agility, and flexibility, all of which also enhanced the firms' capability to mitigate their risks. Originality/value The briefing saves busy executives, strategists and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings The increasing relevance of culture to supply chain management is indicated by the number and scope of studies that currently exist. However, significant shortcomings prevail that might be addressed by the development of an appropriate framework able to measure interaction between individual, organizational and network cultural levels. Originality/value The briefing saves busy executives and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


2018 ◽  
Vol 34 (12) ◽  
pp. 6-8

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings Greater understanding of a business unit’s actual rather than desired supply chain strategy can help identify where changes are needed and ensure it remain closely linked to the wider business strategy. Use of a relevant framework enables the tacit knowledge surrounding the supply chain function to become conceptualized and thus make the supply chain strategy more explicit. Originality/value The briefing saves busy executives and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


Author(s):  
Anne-Mette Hjalager

The purpose of this chapter is to introduce a conceptual approach to understanding driving forces for innovation in sustainable tourism development. The model underpins the fact that innovation in tourism is not solely the effect of a strategic and wilful internal action in tourism firms and organisations, but also the consequences of external driving forces. Further, the article offers a more detailed review of the importance of suppliers as (one of several) push factors for sustainable tourism development. Examples are provided, and possibilities and limitations in terms of a rapid development of more sustainable practices in tourism are discussed. A four-field model aims at stimulating the search for new forms of collaboration between tourism firms and their suppliers in the upstream supply chain, and it adds dimensions to the traditional perspectives on value chains in tourism.


2021 ◽  
Vol 13 ◽  
pp. 101-108
Author(s):  
Yunfan Yang ◽  
Luyao Han ◽  
Bohan Zhang ◽  
Xiong Yang

The rapid development of economic globalization and the promotion of emerging technologies have spawned a Service-oriented logic that gradually dominates the contemporary industry, and the path for manufacturing companies to improve performance has become more and more complicated. Based on this background, the article uses the data of A-share listed companies in the manufacturing industry in the Yangtze River Delta and the Pearl River Delta in 2019, and uses the research method of fuzzy set qualitative comparative analysis to empirically study the core path and mechanism of multiple complex factors that affect corporate performance. The research results show that manufacturing companies can choose four paths to improve corporate performance (supply chain integration-driven based on internal control, servicing and market dual logic based on internal control-based integration-driven, relying on exploration and innovation-based integration-driven, Relying on the integration-driven type of dual innovation and balance), and found that the core role of supply chain integration and servicing level has become more prominent, becoming a key factor leading to high corporate performance. This research is helpful to identify the influence mechanism of supply chain integration, service level and other factors on corporate performance, and grasp the core of configuration, which has certain reference significance for corporate managers.


2021 ◽  
Vol 235 ◽  
pp. 03004
Author(s):  
Chung-Lien Pan ◽  
JiaLong Li ◽  
XiaoLing Huang ◽  
XuanFan Guo ◽  
LiHong Zhang

The process of globalization and digitization has continuously increased customer requirements for logistics costs and services. Issues related to the development of logistics and supply chain has received great attention. However, considering the factors of timeliness and systemic, previous studies could no longer meet the latest needs. To fill these gaps, this article reviews the 833 articles collected from the Web of Science (WoS) database from 1989 to March 2020 and mainly analyzes annual trends, top organizations, top published countries, author keywords, and main sources and disciplines, using the concepts of system thinking and knowledge-intermediary to summarize the research results. The results show that the research on logistics and supply chain is in a period of rapid development, and presents a decentralized and diversified development trend. These data and images provide a comprehensive picture of the development of the digital business economy, aiming to help researchers, funding agencies, policymakers, and industry professionals grasp the timely situation about the discipline, thus establishing a systematic understanding.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings Companies can enhance their supply chain by combining data analytics and the digitization of activities. Manager focus on internal dynamic capabilities and effectiveness of data acquisition and utilization increases the possibility of improved operational and business performance. Originality/value The briefing saves busy executives and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings COVID-19 has had a dramatic and damaging effect on supply chains and distributors. This briefing considers why, and what strategies there may be to cope. Originality/value The briefing saves busy executives, strategists and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


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