scholarly journals Central Nervous System Effects of COVID-19 in People with HIV Infection

2021 ◽  
Author(s):  
Michael J. Peluso ◽  
Joanna Hellmuth ◽  
Felicia C. Chow
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
General Population ◽  
Hiv Infection ◽  
Selective Vulnerability ◽  
The Central Nervous System ◽  
Research Questions ◽  
Cns Effects ◽  
Biologic Factors

AbstractThe convergence of the HIV and SARS-CoV-2 pandemics is an emerging field of interest. In this review, we outline the central nervous system (CNS) effects of COVID-19 in the general population and how these effects may manifest in people with HIV (PWH). We discuss the hypothetical mechanisms through which SARS-CoV-2 could impact the CNS during both the acute and recovery phases of infection and the potential selective vulnerability of PWH to these effects as a result of epidemiologic, clinical, and biologic factors. Finally, we define key research questions and considerations for the investigation of CNS sequelae of COVID-19 in PWH.

scholarly journals Genotypical diversity of HIV clades and central nervous system impairment

2011 ◽  
Vol 69 (6) ◽  
pp. 964-972 ◽  
Author(s):  
Indianara Rotta ◽  
Sérgio Monteiro de Almeida
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hiv Infection ◽  
Opportunistic Infections ◽  
Regulatory Protein ◽  
Viral Meningitis ◽  
Neurological Involvement ◽  
Subtype C ◽  
Vacuolar Myelopathy ◽  
The Central Nervous System

The central nervous system (CNS) and the immune system are considered major target organs for HIV infection. The neurological manifestations directly related to HIV are acute viral meningitis, chronic meningitis, HIV associated dementia, vacuolar myelopathy and involvement of the peripheral nervous system. Changes in diagnosis and clinical management have changed the aspect of HIV infection so that it is no longer a fatal disease, and has become a chronic disease requiring sustained medical management. After HAART the incidence of most opportunistic infections, including those affecting the CNS, has dropped markedly. Some studies suggest that neurological involvement of infected patient occur with different frequency, depending on HIV subtype involved in the infection. Subtype C may have reduced neuroinvasive capacity, possibly due to its different primary conformation of HIV transactivating regulatory protein (Tat), involved in monocyte chemotaxis. This review focus on physiopathologic aspects of HIV infection in CNS and its correlation with HIV clades.

Imaging of the central nervous system in HIV infection

Imaging ◽  
2002 ◽  
Vol 14 (1) ◽  
pp. 48-59 ◽  
Author(s):  
N A Sibtain ◽  
R J S Chinn
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hiv Infection ◽  
The Central Nervous System

B cell responses in HIV infection of the central nervous system

2006 ◽  
Vol 33 (S 1) ◽  
Author(s):  
G. von Geldern ◽  
S. Cepok ◽  
T. Nolting ◽  
V. Grummel ◽  
H.P. Hartung ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hiv Infection ◽  
B Cell ◽  
Cell Responses ◽  
The Central Nervous System ◽  
B Cell Responses

Kidney and Ureteral Disease during HIV Infection

1992 ◽  
Vol 59 (2) ◽  
pp. 46-49
Author(s):  
R. Musci ◽  
T. Meroni ◽  
M. Andres ◽  
O. De Cobelli ◽  
P. Larcher ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hiv Infection ◽  
Acquired Immunodeficiency Syndrome ◽  
Urogenital System ◽  
Hiv Virus ◽  
The Central Nervous System ◽  
Acquired Immunodeficiency ◽  
A Minor ◽  
Immunodeficiency Syndrome

Infection by Hiv virus affects the urogenital system in a minor percentage of cases in comparison to other organs such as the lungs, the central nervous system and the haemolymphopoietic system. In recent years however, with the continued spread of the disease, also urologists find themselves dealing with various urogenital pathologies that are presented in seropositive or fully-blown Aids patients. The Authors present their experience and describe the problems correlated to dealing with acquired immunodeficiency syndrome patients that are affected with urological pathologies.

Treating HIV Infection in the Central Nervous System

Drugs ◽  
2017 ◽  
Vol 77 (2) ◽  
pp. 145-157 ◽  
Author(s):  
A. Calcagno ◽  
G. Di Perri ◽  
S. Bonora
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hiv Infection ◽  
The Central Nervous System
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