Epidemiology and clinical course of primary biliary cholangitis in the Asia–Pacific region: a systematic review and meta-analysis

2019 ◽  
Vol 13 (6) ◽  
pp. 788-799 ◽  
Author(s):  
Na Zeng ◽  
Weijia Duan ◽  
Sha Chen ◽  
Shanshan Wu ◽  
Hong Ma ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sara Ashtari ◽  
Hadis Najafimehr ◽  
Mohamad Amin Pourhoseingholi ◽  
Kamran Rostami ◽  
Hamid Asadzadeh-Aghdaei ◽  
...  

AbstractThis systematic review and meta-analysis study was conducted to estimate the pooled prevalence of CD in low and high risk groups in this region. Following keywords were searched in the Medline, PubMed, Scopus, Web of Science and Cochrane database according to the MeSH terms; celiac disease, prevalence, high risk population and Asian-Pacific region. Prevalence studies published from January 1991 to March 2018 were selected. Prevalence of CD with 95% confidence interval (CI) was calculated using STATA software, version 14. The pooled sero-prevalence of CD among low risk group in Asia–Pacific region was 1.2% (95% CI 0.8–1.7%) in 96,099 individuals based on positive anti-tissue transglutaminase (anti-t-TG Ab) and/or anti-endomysial antibodies (EMA). The pooled prevalence of biopsy proven CD in Asia–Pacific among high and low risk groups was 4.3% (95% CI 3.3–5.5%) and 0.61% (95% CI 0.4–0.8%) in 10,719 and 70,344 subjects, respectively. In addition, the pooled sero-prevalence and prevalence of CD in general population was significantly higher in children compared with adults and it was significantly greater in female vs. male (P < 0.05). Our results suggest high risk individuals of CD are key group that should be specifically targeted for prevention and control measures, and screening may prove to have an optimal cost–benefit ratio.


2017 ◽  
Vol 64 (suppl_2) ◽  
pp. S119-S126 ◽  
Author(s):  
Hitoshi Honda ◽  
Norio Ohmagari ◽  
Yasuharu Tokuda ◽  
Caline Mattar ◽  
David K. Warren

2017 ◽  
Vol 2 (10) ◽  
pp. 707-715 ◽  
Author(s):  
Yu-Ting Kuo ◽  
Jyh-Ming Liou ◽  
Emad M El-Omar ◽  
Jeng-Yih Wu ◽  
Alex Hwong Ruey Leow ◽  
...  

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