Optimization of machining parameters for EDM operations based on central composite design and desirability approach

2014 ◽  
Vol 28 (3) ◽  
pp. 1045-1053 ◽  
Author(s):  
Subramanian Gopalakannan ◽  
Thiagarajan Senthilvelan
Keyword(s):  
Central Composite Design ◽  
Machining Parameters ◽  
Desirability Approach ◽  
Central Composite

scholarly journals Ion Exchange Dialysis for Aluminium Transport through a Face-Centred Central Composite Design Approach

Processes ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 160 ◽  
Author(s):  
Dennis Asante-Sackey ◽  
Sudesh Rathilal ◽  
Lingham V. Pillay ◽  
Emmanuel Kweinor Tetteh
Keyword(s):  
Ion Exchange ◽  
Central Composite Design ◽  
Desirability Function ◽  
Target Response ◽  
Time Zone ◽  
Feed Concentration ◽  
Counter Flow ◽  
The Face ◽  
Desirability Approach ◽  
Central Composite

An ion exchange dialysis (IED) is used in the recovery of aluminium from residue. In this paper, the face-centred central composite design (FC-CCD) of the response surface methodology (RSM) and desirability approach is used for experimental design, modelling and process optimization of a counter flow IED system. The feed concentration, feed flowrate, sweep flowrate and sweep concentration were selected as the process variables, with the Al transport across a Nafion 117 membrane as the target response. A total of 30 experimental runs were conducted with six centre points. The response obtained was analysed by analysis of variance (ANOVA) and fitted to a second-order polynomial model using multiple regression analysis. The actual R2 and standard deviation of the model are 0.9548 and 0.2932, respectively. Depending on the time zone of reference (24 h or 32 h), the highest enrichment of >1.50 was achieved. The designed variables were numerically optimized by applying the desirability function to achieve the maximum Al transport. The optimised condition values were found to be a feed concentration of 1600 ppm, feed flowrate of 61.76%, sweep flowrate of 37.50% and sweep concentration of 0.75 N for the 80% target response at 32 h. Overall, the model can be used to effectively predict Al recovery using the designed system.

scholarly journals Ion Exchange Dialysis for Aluminium Transport through a Face Centered Central Composite Design Approach

2019 ◽  
Author(s):  
Dennis Asante-Sackey ◽  
Sudeh Rathilal ◽  
Lingham V. Pillay ◽  
Emmanuel Kweinor Tetteh
Keyword(s):  
Ion Exchange ◽  
Central Composite Design ◽  
Desirability Function ◽  
Target Response ◽  
Feed Concentration ◽  
The Face ◽  
Contour Plots ◽  
Desirability Approach ◽  
Face Centered ◽  
Central Composite

An ion exchange dialysis (IED) is used in the recovery of aluminium from residue. In this papers, the face-centered central composite design (FC-CCD) of the response surface methodology (RSM) and desirability approach is used for experimental design, modelling and process optimization of a counter flow IED system. The feed concentration, feed flowrate, sweep flowrate and sweep concentration are selected as the process variables, with the Al-transport across a Nafion 117 membrane as the target response. A total of 30 experimental runs were conducted with 6 center points. The response obtained was analysed by analysis of variance (ANOVA) and fitted to a second-order polynomial model using multiple regression analysis. The actual R2 and standard deviation of the model are 0.9548 and 0.2932 respectively. The influences of significant variables are plotted on 3D surface and contour plots. The designed variables were numerically optimized by applying the desirability function to achieve the maximum Al-transport. The optimised condition values were found to be feed concentration (1600 ppm), feed flowrate (61.76%), sweep flowrate (37.50%) and sweep concentration (0.75 N) for the 80% target response at 32hrs. Overall, the model can be used to effectively predict Al-recovery using the designed system

scholarly journals Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 370
Author(s):  
Maria Rosa Gigliobianco ◽  
Barbara Campisi ◽  
Dolores Vargas Peregrina ◽  
Roberta Censi ◽  
Gulzhan Khamitova ◽  
...  
Keyword(s):  
Solvent Extraction ◽  
Cell Viability ◽  
Central Composite Design ◽  
Extraction Process ◽  
Extraction Temperature ◽  
Hacat Cells ◽  
Spent Coffee Grounds ◽  
Coffee Grounds ◽  
Desirability Approach ◽  
Central Composite

The purpose of this work was the optimization of the extraction from spent coffee grounds, specifically 100% Arabica coffee blends, using a desirability approach. Spent coffees were recovered after the preparation of the espresso coffee under the typical conditions used in coffee bars with a professional machine. Spent coffee was subjected to different extraction procedures in water: by changing the extraction temperature (60, 80, or 100 °C) and the solvent extraction volume (10, 20, 30 mL for 1 g of coffee) and by maintaining constant the extraction time (30 min). The ranges of the process parameters, as well as the solvent to be used, were established by running preliminary experiments not reported here. The variables of interest for the experimental screening design were the content of caffeine, trigonelline, and nicotinic acid, quantitatively determined from regression lines of standard solutions of known concentrations by a validated HPLC-VWD method. Since solvent extraction volumes and temperatures were revealed to be the most significant process variables, for the optimization of the extraction process, an approach based on Response Surface Methodology (RSM) was considered. In particular, a Box-Wilson Central Composite Design, commonly named central composite design (CCD), was used to find the optimal conditions of the extraction process. Moreover, the desirability approach was then applied to maximize the extraction efficiency by searching the optimal values (or at least the best compromise solution) for all three response variables simultaneously. Successively, the best extract, obtained in a volume of 20 mL of water at an extraction temperature of 80 °C, was analyzed for total phenol content (TPC) through the Folin–Ciocalteu assay, and the antioxidant capacities (AC) through the trolox equivalent (TE) antioxidant capacity (DPPH), ferric-ion reducing antioxidant parameter (FRAP), and radical cation scavenging activity and reducing power (ABTS). The TPC and the AC for spent coffee were high and comparable to the results obtained in previous similar studies. Then, the extract was evaluated by inductively coupled plasma mass spectrometry (ICP–MS), revealing that potassium was the most abundant element, followed by phosphorus, magnesium, calcium, sodium, and sulfur, while very low content in heavy metals was observed. Preliminary in vitro assays in keratinocyte HaCaT cells were carried out to assess the safety, in terms of cytotoxicity of spent coffee, and results showed that cell viability depends on the extract concentration: cell viability is unmodified up to a concentration of 0.3 mg/mL, over which it becomes cytotoxic for the cells. Spent coffee extract at 0.03 and 0.3 mg/mL showed the ability to reduce intracellular reactive oxygen species formation induced by hydrogen peroxide in HaCaT cells, suggesting its antioxidant activity at intracellular levels.

scholarly journals Dataset on optimization of EDM machining parameters by using central composite design

Data in Brief ◽  
2019 ◽  
Vol 23 ◽  
pp. 103671 ◽  
Author(s):  
A. Soundhar ◽  
H. Abdul Zubar ◽  
Mohamed Thariq Bin Haji Hameed Sultan ◽  
Jayakrishna Kandasamy
Keyword(s):  
Central Composite Design ◽  
Machining Parameters ◽  
Central Composite

Evaluating effective factors on the activity and loading of immobilized α-amylase onto magnetic nanoparticles using a response surface-desirability approach

RSC Advances ◽  
2016 ◽  
Vol 6 (24) ◽  
pp. 20187-20197 ◽  
Author(s):  
F. Eslamipour ◽  
P. Hejazi
Keyword(s):  
Magnetic Nanoparticles ◽  
Central Composite Design ◽  
Response Surface ◽  
Covalent Immobilization ◽  
Effective Factors ◽  
Operational Conditions ◽  
Desirability Approach ◽  
Central Composite

The effects of different operational conditions of α-amylase covalent immobilization on magnetic nanoparticles were investigated using a central composite design.

Development and optimization of solid lipid nanoparticles of amikacin by central composite design

2009 ◽  
Vol 00 (00) ◽  
pp. 090721051030036-8
Author(s):  
Jaleh Varshosaz ◽  
Solmaz Ghaffari ◽  
Mohammad Reza Khoshayand ◽  
Fatemeh Atyabi ◽  
Shirzad Azarmi ◽  
...  
Keyword(s):  
Central Composite Design ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
Central Composite
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