Characteristics, Controlled-release and Antimicrobial Properties of Tea Tree Oil Liposomes-incorporated Chitosan-based Electrospun Nanofiber Mats

2019 ◽  
Vol 20 (4) ◽  
pp. 698-708 ◽  
Author(s):  
Yan Ge ◽  
Jiapeng Tang ◽  
Haihong Fu ◽  
Yijun Fu ◽  
Yuanyuan Wu
2013 ◽  
Vol 10 (12) ◽  
pp. 4509-4526 ◽  
Author(s):  
S. Khansari ◽  
S. Duzyer ◽  
S. Sinha-Ray ◽  
A. Hockenberger ◽  
A. L. Yarin ◽  
...  

Polymers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2034 ◽  
Author(s):  
Tomasz Kozior ◽  
Al Mamun ◽  
Marah Trabelsi ◽  
Martin Wortmann ◽  
Sabantina Lilia ◽  
...  

Electrospinning is a frequently used method to prepare air and water filters. Electrospun nanofiber mats can have very small pores, allowing for filtering of even the smallest particles or molecules. In addition, their high surface-to-volume ratio allows for the integration of materials which may additionally treat the filtered material through photo-degradation, possess antimicrobial properties, etc., thus enhancing their applicability. However, the fine nanofiber mats are prone to mechanical damage. Possible solutions include reinforcement by embedding them in composites or gluing them onto layers that are more mechanically stable. In a previous study, we showed that it is generally possible to stabilize electrospun nanofiber mats by 3D printing rigid polymer layers onto them. Since this procedure is not technically easy and needs some experience to avoid delamination as well as damaging the nanofiber mat by the hot nozzle, here we report on the reversed technique (i.e., first 3D printing a rigid scaffold and subsequently electrospinning the nanofiber mat on top of it). We show that, although the adhesion between both materials is insufficient in the case of a common rigid printing polymer, nanofiber mats show strong adhesion to 3D printed scaffolds from thermoplastic polyurethane (TPU). This paves the way to a second approach of combining 3D printing and electrospinning in order to prepare mechanically stable filters with a nanofibrous surface.


2021 ◽  
Vol 13 (9) ◽  
pp. 4827
Author(s):  
Mursleen Yasin ◽  
Adnan Younis ◽  
Fahad Ramzan ◽  
Talha Javed ◽  
Rubab Shabbir ◽  
...  

Tea tree oil (TTO) from the genus Melaleuca L. has antimicrobial, antibacterial, antifungal, and antioxidant properties and is used by the cosmetic, pharmaceutical, and horticultural industries. In Pakistan, Melaleuca bracteata can be exploited for essential oil purposes, as this species is well adapted to Pakistan’s agroclimatic conditions. The objective of the present study was to evaluate the yield of M. bracteata essential oil together with its antioxidant and antimicrobial properties under local prevailing conditions of the subtropics. Essential oil was extracted through the hydrodistillation method. Using this method, six batches of 8 kg samples (fresh leaves and branches) underwent a distillation process for 4–5 h. The average yield obtained was about 0.2%. The GCMS was used to identify the components of extracted essential oil. Eugenol methyl ether is the major component in extracted essential oil, i.e., 96% of the total. A high content of flavonoids and phenolics and a Fe-reducing power ability of M. bracteata were observed. The oil was also found effective against B. subtilis, B. cereus, White rot, and A. flavus. Hence, it is concluded that there is a possibility to use TTO for its biocidal properties, and it must also be inspected and then commercialized in Pakistan by the agriculture and cosmetic industries.


Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1091
Author(s):  
Thabata Muta ◽  
Ankit Parikh ◽  
Krishna Kathawala ◽  
Hanif Haidari ◽  
Yunmei Song ◽  
...  

Despite the promising properties of tea tree oil (TTO) as potential therapeutics for several superficial skin conditions, certain limitations such as physical instability and skin irritation have restricted its widespread use. This study focuses on developing a rationally designed lipid-based nanoformulation (TTO-LNF) in accordance with the US Food and Drug Administration standard using a well-recognized quality-by-design (QbD) approach. Using a mixture experimental design, TTO-LNF has been optimized with 5% TTO, 10% surfactant, 5% co-surfactant, and 80% water, which showed a 14.4 ± 4.4 nm droplet size and 0.03 ± 0.01 polydispersity index (PDI). To ease the topical administration, the TTO-LNF gel formulation was further developed using xanthan gum to achieve the desired viscosity and form a gel. The in vitro antibacterial tests of TTO-LNF showed promising inhibitory effects toward both Gram-negative and Gram-positive bacteria. In fact, a complete growth inhibition of S. epidermidis was observed when exposed to TTO-LNF and TTO-LNF gel for 24 h, showing better activity than antibiotic kanamycin (25 µg/mL). Additionally, the in vitro release study showed a sustained release profile with a 50% release in 24 h, which could be beneficial to reduce the toxicity and thereby improve the therapeutic efficacy for long-acting applications. Furthermore, the formulations were remarkably stable at 40 °C/75% Relative humidity (RH) for at least 4 weeks. Therefore, this study presents a promising strategy to develop a biocompatible and stable formulation that can be used for the topical treatment of skin infections.


Pathology ◽  
2001 ◽  
Vol 33 (2) ◽  
pp. 211-215 ◽  
Author(s):  
John E. Gustafson ◽  
Sean D. Cox ◽  
Yoon C. Liew ◽  
S. Grant Wyllie ◽  
John R. Warmington

Planta Medica ◽  
2015 ◽  
Vol 81 (05) ◽  
Author(s):  
S Liang ◽  
Z Ali ◽  
M Wang ◽  
IA Khan
Keyword(s):  
Tea Tree ◽  

2020 ◽  
Vol 16 (3) ◽  
pp. 34-38
Author(s):  
Z.K. Batyrova ◽  
◽  
E.V. Uvarovа ◽  
Z.Kh. Kumykova ◽  
A.K. Dzhangischieva ◽  
...  

2005 ◽  
Vol 89 (11) ◽  
pp. 1468-1473 ◽  
Author(s):  
Y-Y Gao
Keyword(s):  

Aquaculture ◽  
2021 ◽  
pp. 736954
Author(s):  
Tamires R. dos Reis ◽  
Matheus D. Baldissera ◽  
Carine F. Souza ◽  
Bernardo Baldisserotto ◽  
Julia Corá Segat ◽  
...  

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