In this study, an extended state observer–based backstepping fast terminal sliding mode control is developed for the ride comfort of a full-car active suspension system. In the referred extended state observer–based backstepping fast terminal sliding mode control, the extended state observer is designed to estimate the lumped disturbances of external road excitation and uncertain dynamics. Then, a backstepping fast terminal sliding mode controller is used to track the desired trajectory reference which is obtained via a nonlinear filter. A virtual prototype of vehicle suspension is also built on ADAMS software as the simulated real-time controlled system. The co-simulation results of MATLAB/Simulink+ADAMS show that the proposed controller has better performance than the passive suspension and the active suspension using the traditional backstepping method whether under random road or bumpy road.