Bacteriological Profile of Patients with Intra-Abdominal Sepsis and Superficial Surgical Site Infection Following Emergency Abdominal Surgery—Is It Concordant?

2020 ◽  
Vol 82 (5) ◽  
pp. 905-911
Author(s):  
Ridhima Aggarwal ◽  
A R Pranavi ◽  
Mohsina Subair ◽  
Sathasivam SureshKumar ◽  
G. S. Sreenath ◽  
...  
Keyword(s):  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Abdominal Sepsis ◽  
Site Infection ◽  
Bacteriological Profile ◽  
Emergency Abdominal Surgery

scholarly journals Surgical Site Infection After Emergency Abdominal Surgery in China: A Multicenter Prospective Study

2020 ◽  
Author(s):  
Ze Li ◽  
Hui Li ◽  
Pin Lv ◽  
Xingang Peng ◽  
Changliang Wu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Length Of Stay ◽  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Secondary Outcome ◽  
Microbial Culture ◽  
Site Infection ◽  
High Blood Glucose ◽  
Emergency Abdominal Surgery

Abstract Background There is still a lack of relevant studies on surgical site infection (SSI) after emergency abdominal surgery (EAS) in China. This study aims to understand the status of SSI after EAS in China and discuss its risk factors. Materials and Methods All adult patients who underwent EAS in 47 hospitals in China from May 1 to 31, 2018, and from May 1 to June 7, 2019, were enrolled in this study. The basic information, perioperative data, and microbial culture results of infected incision were prospectively collected.The primary outcome measure was the incidence of SSI after EAS, and the secondary outcome variables were postoperative length of stay, ICU admission rate, ICU length of stay, 30-day postoperative mortality, and treatment costs. Univariate and multivariate logistic regression were used to analyze the risk factors.Results A total of 953 patients (age 48.8 ± 17.9 years, male 51.9%) with EAS were included in this study: 71 patients (7.5%) developed SSI after surgery.The main pathogen of SSI was Escherichia coli (culture positive rate 29.6%). Patients with SSI had significantly longer overall hospital (p < 0.001) and ICU stays (p < 0.001), significantly higher ICU admissions (p < 0.001), and medical costs (p < 0.001) than patients without SSI.Multivariate logistic regression analysis showed that male (P = 0.010), high blood glucose level (P < 0.001), colorectal surgery (P < 0.001), intestinal obstruction (P = 0.045) and surgical duration (P = 0.007) were risk factors for SSI, whereas laparoscopic surgery (P < 0.001 = 0.022) was a protective factor. Conclusion This study found a high incidence of SSI after EAS in China. The occurrence of SSI prolongs the patient's hospital stay and increases the medical burden. The study also revealed predictors of SSI after EAS and provides a basis for the development of norms for the prevention of surgical site infection after emergency abdominal surgery.

scholarly journals Prospective multicenter study on the incidence of surgical site infection after emergency abdominal surgery in China

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ze Li ◽  
Hui Li ◽  
Pin Lv ◽  
Xingang Peng ◽  
Changliang Wu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Length Of Stay ◽  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Secondary Outcome ◽  
Site Infection ◽  
Multivariate Logistic Regression ◽  
High Blood Glucose ◽  
Emergency Abdominal Surgery

AbstractThere is still a lack of relevant studies on surgical site infection (SSI) after emergency abdominal surgery (EAS) in China. This study aims to understand the incidence of SSI after EAS in China and discuss its risk factors. All adult patients who underwent EAS in 47 hospitals in China from May 1 to 31, 2018, and from May 1 to June 7, 2019, were enrolled in this study. The basic information, perioperative data, and microbial culture results of infected incision were prospectively collected. The primary outcome measure was the incidence of SSI after EAS, and the secondary outcome variables were postoperative length of stay, ICU admission rate, ICU length of stay, 30-day postoperative mortality, and hospitalization cost. Univariate and multivariate logistic regression were used to analyze the risk factors. The results were expressed as the odds ratio and 95% confidence interval. A total of 953 patients [age 48.8 (SD: 17.9), male 51.9%] with EAS were included in this study: 71 patients (7.5%) developed SSI after surgery. The main pathogen of SSI was Escherichia coli (culture positive rate 29.6%). Patients with SSI had significantly longer overall hospital (p < 0.001) and ICU stays (p < 0.001), significantly higher ICU admissions (p < 0.001), and medical costs (p < 0.001) than patients without SSI. Multivariate logistic regression analysis showed that male (P = 0.010), high blood glucose level (P < 0.001), colorectal surgery (P < 0.001), intestinal obstruction (P = 0.045) and surgical duration (P = 0.007) were risk factors for SSI, whereas laparoscopic surgery (P < 0.001) was a protective factor. This study found a high incidence of SSI after EAS in China. The occurrence of SSI prolongs the patient's hospital stay and increases the medical burden. The study also revealed predictors of SSI after EAS and provides a basis for the development of norms for the prevention of surgical site infection after emergency abdominal surgery.

scholarly journals SUPERFICIAL SURGICAL SITE INFECTION IN EMERGENCY ABDOMINAL SURGICAL PROCEDURES. A REANALYSIS OF MICROBIOLOGY AND ANTIBIOTIC SENSITIVITY

1969 ◽  
Vol 5 (1) ◽  
pp. 617-620
Author(s):  
ZEESHAN SABOOR AHMED ◽  
MUHAMMAD IFTIKHAR ◽  
IRFANUL ISLAM NASIR ◽  
MUHAMMAD KHAN ◽  
NAYAB SARWAR
Keyword(s):  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Wound Infection ◽  
Antibiotic Sensitivity ◽  
Site Infection ◽  
Cross Sectional ◽  
The Common ◽  
Clean Contaminated ◽  
Hospital Acquired ◽  
Emergency Abdominal Surgery

BACKGROUND: Surgical site infection is regarded as the most common hospital acquired infectionsamong the surgical patients and carries a significant impact on patient’s morbidity and mortality.OBJECTIVES: The aims of this study were to know about the common pathogens causing surgical siteinfection after emergency abdominal surgery and their sensitivity to various antibiotic groups.METHODOLOGY: This was a prospective cross sectional observational study of 6 months duration,carried out from July 2012 to December 2012 in the department of general surgery, Hayatabad MedicalComplex, Peshawar. All the patients who underwent emergency abdominal surgery during this periodwere included in the study. Wounds were classified as clean, clean contaminated, contaminated anddirty. Superficial Surgical site infection was diagnosed using the criteria set by the Center for DiseaseControl and classified according to the Southampton scoring system.RESULTS: A total of 256 emergency abdominal surgeries were performed. Out of these, 37 patientsdeveloped wound infection, showing that 14.45% of the patients undergoing emergency abdominalsurgery developed wound infection. The culture report suggested E.coli as the most common pathogenaccounting for 19(51.35%) cases of SSI followed by pseudomonas, Staph.aureus and klebsiellaaccounting for 8(21.62%) cases, 6(16.21%) cases and 1(2.7%) cases respectively. No growth wasobtained in 2(5.4%) cases and mix growth was obtained in 1(2.7%).CONCLUSION: Gram negative flora of the gut is responsible for SSI in emergency surgicalprocedures and this flora is most sensitive to pipercillin/tazobactam, cefoparazone/sulbactam andmeropenam.KEY WORDS: Surgical site infection, pathogen, emergency abdominal surgery

scholarly journals Feasibility and diagnostic accuracy of Telephone Administration of an adapted wound heaLing QuestiONnaire for assessment for surgical site infection following abdominal surgery in low and middle-income countries (TALON): protocol for a study within a trial (SWAT)

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
◽  
James Glasbey ◽  
Victoria Adeyeye ◽  
Adesoji Ademuyiwa ◽  
Alisha Bhatt ◽  
...  
Keyword(s):  
Wound Healing ◽  
Abdominal Surgery ◽  
Diagnostic Accuracy ◽  
Surgical Site Infection ◽  
Hospital Discharge ◽  
Site Infection ◽  
Middle Income ◽  
Middle Income Countries ◽  
Wound Assessment ◽  
Study Within A Trial

Abstract Background Surgical site infection is the most common complication of abdominal surgery, with a global impact on patients and health systems. There are no tools to identify wound infection that are validated for use in the global setting. The overall aim of the study described in this protocol is to evaluate the feasibility and validity of a remote, digital pathway for wound assessment after hospital discharge for patients in low- and middle-income countries (LMICs). Methods A multi-centre, international, mixed-methods study within a trial, conducted in two stages (TALON-1 and TALON-2). TALON-1 will adapt and translate a universal reporter outcome measurement tool (Bluebelle Wound Healing Questionnaire, WHQ) for use in global surgical research (SWAT store registration: 126) that can be delivered over the telephone. TALON-2 will evaluate a remote wound assessment pathway (including trial retention) and validate the diagnostic accuracy of this adapted WHQ through a prospective cohort study embedded within two global surgery trials. Embedded community engagement and involvement activities will be used to optimise delivery and ensure culturally attuned conduct. TALON-1 and TALON-2 are designed and will be reported in accordance with best practice guidelines for adaptation and validation of outcome measures, and diagnostic test accuracy studies. Discussion Methods to identify surgical site infection after surgery for patients after hospital discharge have the potential to improve patient safety, trial retention, and research efficiency. TALON represents a large, pragmatic, international study co-designed and delivered with LMIC researchers and patients to address an important research gap in global surgery trial methodology.

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