Serum vitamin D concentration and short-term mortality among geriatric inpatients in acute care settings

2010 ◽  
Vol 27 (4) ◽  
pp. 245-249 ◽  
Author(s):  
Cédric Annweiler ◽  
Sophie Pochic ◽  
Bruno Fantino ◽  
Erick Legrand ◽  
Régis Bataille ◽  
...  
Keyword(s):  
Vitamin D ◽  
Acute Care ◽  
Serum Vitamin ◽  
Short Term ◽  
Serum Vitamin D ◽  
Short Term Mortality ◽  
Acute Care Settings ◽  
Geriatric Inpatients

scholarly journals Changes in serum vitamin D and PTH values using denosumab with or without bisphosphonate pre-treatment in osteoporotic patients: a short-term study

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Yukio Nakamura ◽  
Mikio Kamimura ◽  
Shota Ikegami ◽  
Keijiro Mukaiyama ◽  
Shigeharu Uchiyama ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Short Term ◽  
Term Study ◽  
Serum Vitamin D ◽  
Short Term Study ◽  
Pre Treatment

scholarly journals Understanding the role of emerging vitamin D biomarkers on short-term persistence of high-risk HPV infection among mid-adult women

2020 ◽  
Author(s):  
Catherine Troja ◽  
Andrew N Hoofnagle ◽  
Adam Szpiro ◽  
Joshua E Stern ◽  
John Lin ◽  
...  
Keyword(s):  
Vitamin D ◽  
High Risk ◽  
Serum Vitamin ◽  
Hpv Infection ◽  
Sensitivity Analyses ◽  
Adult Women ◽  
Short Term ◽  
Serum Vitamin D ◽  
Multiple Biomarkers ◽  
Free Vitamin D

Abstract Background Associations between vitamin D biomarkers and persistent high-risk human papillomavirus (hrHPV) detection have not been evaluated. Methods 2011-2012 stored sera from 72 women ages 30-50 years with prevalent hrHPV (n=116 type-specific infections) were tested for 5 vitamin D biomarkers: 25(OH)D and 4 emerging biomarkers, 1,25(OH)2D, 24,25(OH)2D, free vitamin D, and vitamin D binding protein (DBP). hrHPV detection patterns (persistent versus transient/sporadic) were determined using cervicovaginal swabs collected monthly for 6 months. Associations between vitamin D and short-term type-specific hrHPV persistence were estimated using logistic regression. Our primary exposure was continuous 25(OH)D, with additional biomarkers evaluated as secondary exposures. Primary models adjusted for age, race, BMI, education, contraceptives, smoking, season, and calcium/phosphate levels. Sensitivity analyses restricted from 19 hrHPV types to 14 used in cervical cancer screening. Results In primary analyses, non-significant positive associations with hrHPV persistence were observed for measures of 25(OH)D and 24,25(OH)2D. Associations were stronger and significant restricting to 14 hrHPV types (25(OH)D per 10ng/mL increase: aOR=1.82,95%CI:1.15-2.88 and aOR=4.19,95%CI:1.18-14.88 DBP-adjusted; 25(OH)D≥30 vs <30ng/mL: aOR=8.85,95%CI:2.69-29.06; 24,25(OH)2D: aOR=1.85,95%CI:1.18-2.88). 1,25(OH)2D was unassociated with persistence. Conclusions Serum vitamin D measured by multiple biomarkers showed positive associations with short-term hrHPV persistence that were significant only when restricting to 14 clinically-relevant hrHPV types.

Vitamin D and Multiple Sclerosis

2011 ◽  
Vol 25 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Nicole Marie Summerday ◽  
Sherrill J. Brown ◽  
Douglas R. Allington ◽  
Michael P. Rivey
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Animal Studies ◽  
Serum Vitamin ◽  
Vitamin D Supplementation ◽  
Epidemiological Evidence ◽  
Short Term ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
True Relationship

There has been growing interest in determining environmental risk factors that may play a role in the development or progression of multiple sclerosis (MS). Epidemiological evidence and data from human and animal studies have shown an association between low serum vitamin D levels and an increased incidence of MS and that supplementation with vitamin D may protect against MS development and/or disease relapses. The most appropriate vitamin D dosage for patients with MS is unclear, but investigators have proposed that serum vitamin D concentrations between 75 and 100 nmol/L (30-40 ng/mL) are optimal to achieve favorable clinical outcomes. Vitamin D supplemented in doses up to 3000 International Units (IU) daily may be necessary to achieve these levels in many patients, and doses of 500 to 800 IU daily appear to be necessary to maintain desired serum vitamin D levels. Short-term supplementation with doses up to 40 000 IU daily has been found to be safe. However, larger and longer clinical studies are needed to assess whether a true relationship exists between serum vitamin D concentrations and MS and to determine a safe and effective amount of vitamin D supplementation.

Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience

2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Model Assessment ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Female Sex ◽  
Vitamin D Levels

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.

Relationship Between Nutrient Intake and Vitamin D Status in Osteoporotic Women

2007 ◽  
Vol 77 (6) ◽  
pp. 376-381 ◽  
Author(s):  
de Souza Genaro ◽  
de Paiva Pereira ◽  
de Medeiros Pinheiro ◽  
Szejnfeld ◽  
Araújo Martini
Keyword(s):  
Vitamin D ◽  
Mineral Metabolism ◽  
Sodium Intake ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Dietary Intakes ◽  
Mineral Density ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Dietary Records

Vitamin D is essential for maintaining calcium homeostasis and optimizing bone health. Its inadequacy is related to many factors including dietary intake. The aim of the present study was to evaluate serum 25(OH)D and its relationship with nutrient intakes in postmenopausal Brazilian women with osteoporosis. This cross-sectional study comprised 45 free-living and assisted elderly at São Paulo Hospital. Three-day dietary records were used to assess dietary intakes. Bone mineral density was measured with a dual-energy X-ray absorptiometer (DXA). Blood and urine sample were collected for analysis of biochemical markers of bone and mineral metabolism. Insufficiency of vitamin D was observed in 24.4% of the women and optimal levels (≥ 50 nmol/L) were observed in 75.6%. Parathyroid hormone was above the reference range in 51% of the participants. The mean calcium (724 mg/day) and vitamin D (4.2 μ g/day) intakes were lower than the value proposed by The Food and Nutrition Board and sodium intake was more than two-fold above the recommendation. Higher levels of serum 25(OH)D were inversely associated with sodium intake. Dietary strategies to improve serum vitamin D must focus on increasing vitamin D intake and should take a reduction of sodium intake into consideration.

Evaluation of the hormonal and biochemical changes in obese and non-obese PCOS Iraqi women before and after vitamin D supplementation

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Suaad Muhssen Ghazi ◽  
Fatin Shallal Farhan
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Follicular Development ◽  
High Body Mass Index ◽  
Vitamin D Supplementation ◽  
The Body ◽  
Obese People ◽  
Serum Vitamin D ◽  
Before And After ◽  
Granulose Cells

Vitamin D deficiency is common in women with polycystic ovarian syndrome. Vitamin D plays an important physiologic role in reproductive functions of ovarian follicular development and luteinization through altering anti-müllerian hormone signaling, follicular stimulating hormone activity and progesterone production in human granulose cells. Vitamin D is precipitated in adipose fat tissues, making it notable to be used for the body as a result; obese people with high body mass index are already highly expected to have low levels of serum vitamin D.

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