The Role of Anxiety Sensitivity in the Relation Between Pain Intensity with Substance Use and Anxiety and Depressive Symptoms Among Smokers with Chronic Pain

This study investigated the mediating role of depressive symptoms among 147 middle-aged and older adults with FM in the relationship between pain intensity and 4 objective measures of physical performance: Fullerton Advanced Balance scale (FAB), 6-Minute Walk Test (6MWT), 30-Second Chair Stand (30SCS), and 8-Foot Up and Go Test (8FUPGT). Asymptotic mediation analyses revealed that depressive symptoms fully mediated the relationship between pain intensity and FAB (95% CI [−0.40, −0.10]) and 8FUPGT (CI [0.02, 0.11]) and partially mediated the relationship to 6MWT (CI [−9.15, −2.20]) and 30SCS (CI [−0.29, −0.06]). Findings support the evaluation of co-morbid depression in FM.

Download Full-text

The role of chronic pain and current substance use in predicting negative social support among disadvantaged persons living with HIV/AIDS

AIDS Care ◽

10.1080/09540121.2016.1168916 ◽

2016 ◽

Vol 28 (10) ◽

pp. 1280-1286 ◽

Cited By ~ 7

Author(s):

Mary M. Mitchell ◽

Allysha C. Maragh-Bass ◽

Trang Q. Nguyen ◽

Sarina Isenberg ◽

Amy R. Knowlton

Keyword(s):

Social Support ◽

Chronic Pain ◽

Substance Use ◽

Persons Living With Hiv ◽

Living With Hiv ◽

Hiv Aids

Download Full-text

Effect of Caffeine on Leg-Muscle Pain during Intense Cycling Exercise: Possible Role of Anxiety Sensitivity

International Journal of Sport Nutrition and Exercise Metabolism ◽

10.1123/ijsnem.18.2.103 ◽

2008 ◽

Vol 18 (2) ◽

pp. 103-115 ◽

Cited By ~ 27

Author(s):

Rachael C. Gliottoni ◽

Robert W. Motl

Keyword(s):

Pain Intensity ◽

Anxiety Sensitivity ◽

High Intensity ◽

Muscle Pain ◽

Caffeine Ingestion ◽

Cycling Exercise ◽

College Age ◽

Peak Aerobic Capacity ◽

Leg Muscle

This experiment examined the effect of a moderate dose of caffeine on perceptions of leg-muscle pain during a bout of high-intensity cycling exercise and the role of anxiety sensitivity in the hypoalgesic effect of caffeine on muscle pain during exercise. Sixteen college-age women ingested caffeine (5 mg/kg body weight) or a placebo and 1 hr later completed 30 min of cycling on an ergometer at 80% of peak aerobic capacity. The conditions were completed in a counterbalanced order, and perceptions of leg-muscle pain were recorded during the bouts of exercise. Caffeine resulted in a large reduction in leg-muscle pain-intensity ratings compared with placebo (d = −0.95), and the reduction in leg-muscle pain-intensity ratings was larger in those with lower anxiety-sensitivity scores than those with higher anxiety-sensitivity scores (d = −1.28 based on a difference in difference scores). The results support that caffeine ingestion has a large effect on reducing leg-muscle pain during high-intensity exercise, and the effect is moderated by anxiety sensitivity.

Download Full-text

Transdiagnostic Cognitive Processes in Chronic Pain and Comorbid PTSD and Depression in Veterans

Annals of Behavioral Medicine ◽

10.1093/abm/kaab033 ◽

2021 ◽

Author(s):

Melissa A Day ◽

Rhonda M Williams ◽

Aaron P Turner ◽

Dawn M Ehde ◽

Mark P Jensen

Keyword(s):

Chronic Pain ◽

Depressive Symptoms ◽

Pain Intensity ◽

Cognitive Processes ◽

Cognitive Process ◽

Stress Disorder ◽

Secondary Analysis ◽

Lower Pain ◽

Depression Scales ◽

Ptsd Group

Abstract Background Chronic pain in Veterans is a major problem compounded by comorbid posttraumatic stress disorder (PTSD) and depression. Adopting a transdiagnostic framework to understanding “shared territory” among these diagnoses has the potential to inform our understanding of the underlying cognitive processes and mechanisms that transverse diagnostic boundaries. Purpose To examine the associations between pain-related cognitive processes (diversion, distancing, absorption, and openness), pain intensity, PTSD and depressive symptoms, and the extent to which Veterans with chronic pain with and without comorbid PTSD and depression engage in different/similar pain-related cognitive processes. Methods Secondary analysis of pretreatment data with a subsample (n = 147) of Veterans with chronic pain from a larger clinical trial. Pretreatment PCL-5 and PROMIS Depression scales were used to categorize participants into three groups: (a) Pain-only; (b) Pain-PTSD; and (c) Pain-PTSD-DEP. Results Compared to the Pain-only group, the Pain-PTSD and Pain-PTSD-DEP groups reported significantly greater pain intensity, PTSD and depressive symptoms, and ruminative pain absorption. The Pain-PTSD-DEP group had significantly lower pain diversion and pain openness scores. When diversion and openness were used within the Pain-PTSD-DEP group, however, they were both associated with lower pain intensity and openness was additionally associated with lower PTSD scores. However, in the Pain-PTSD group, pain openness was associated with higher depression scores. Conclusions Across increasing complexity of comorbidity profiles (i.e., one vs. two comorbid conditions), ruminative absorption with pain emerged as a cognitive process that transverses diagnoses and contributes to worse outcomes. Nonjudgmental acceptance may not be universally beneficial, potentially depending upon the nature of comorbidity profiles.

Download Full-text