Impact of malnutrition on physical, cognitive function and mortality among older men living in veteran homes by minimum data set: A prospective cohort study in Taiwan

2016 ◽  
Vol 20 (1) ◽  
pp. 41-47 ◽  
Author(s):  
L.-Y. Chen ◽  
L.-K. Liu ◽  
A.-C. Hwang ◽  
M.-H. Lin ◽  
L.-N. Peng ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cognitive Function ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Older Men ◽  
Minimum Data Set ◽  
Data Set ◽  
Minimum Data

Fine or Gross Motor Index as a Simple Tool for Predicting Cognitive Impairment in Elderly People: Findings from The Irish Longitudinal Study on Ageing (TILDA)

2021 ◽  
pp. 1-8
Author(s):  
Xiao Liu ◽  
Ayiguli Abudukeremu ◽  
Yuan Jiang ◽  
Zhengyu Cao ◽  
Maoxiong Wu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cognitive Impairment ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Simple Tool

Background: Several kinds of motor dysfunction can predict future cognitive impairment in elderly individuals. However, the ability of the fine motor index (FINEA) and gross motor index (GROSSA) to predict the risk of cognitive impairment has not been assessed. Objective: We investigated the associations between FINEA/GROSSA and cognitive impairment. Methods: The data of 4,745 participants from The Irish Longitudinal Study on Ageing (TILDA) were analyzed. Cognitive function was assessed using the Mini-Mental State Examination (MMSE). We first assessed the correlation between the FINEA GROSSA and MMSE in a cross-sectional study. Then, we further investigated the predictive role of the incidence of cognitive impairment in a prospective cohort study. Results: We found that both FINEA and GROSSA were negatively correlated with MMSE in both the unadjusted (FINEA: B = –1.00, 95%confidence intervals (CI): –1.17, –0.83, t = –11.53, p <  0.001; GROSSA: B = –0.85, 95%CI: –0.94, –0.76, t = –18.29, p <  0.001) and adjusted (FINEA: B = –0.63, 95%CI: –0.79, –0.47, t = –7.77, p <  0.001; GROSSA: B = –0.57, 95%CI: –0.66, –0.48, t = –12.61, p <  0.001) analyses in a cross-sectional study. In a prospective cohort study, both high FINEA and high GROSSA were associated with an increased incidence of cognitive function impairment (FINEA: adjusted odds ratios (OR) = 2.35, 95%CI: 1.05, 5.23, p = 0.036; GROSSA adjusted OR = 3.00, 95%CI: 1.49, 6.03, p = 0.002) after 2 years of follow-up. Conclusion: Higher FINEA and GROSSA scores were both associated with an increased incidence of cognitive impairment. FINEA or GROSSA might be a simple tool for identifying patients with cognitive impairment.

Cognitive Function 3 and 12 Months After ICU Discharge—A Prospective Cohort Study

2018 ◽  
Vol 46 (12) ◽  
pp. e1121-e1127 ◽  
Author(s):  
Stine Estrup ◽  
Cilia K. W. Kjer ◽  
Frederik Vilhelmsen ◽  
Lone M. Poulsen ◽  
Ismail Gøgenur ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cognitive Function ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Icu Discharge

scholarly journals The Association Between Protein Intake by Source and Osteoporotic Fracture in Older Men: A Prospective Cohort Study

2017 ◽  
Vol 32 (3) ◽  
pp. 592-600 ◽  
Author(s):  
Lisa Langsetmo ◽  
James M Shikany ◽  
Peggy M Cawthon ◽  
Jane A Cauley ◽  
Brent C Taylor ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Osteoporotic Fracture ◽  
Prospective Cohort ◽  
Protein Intake ◽  
Older Men

scholarly journals Physical activity and vascular disease in a prospective cohort study of older men: The Health In Men Study (HIMS)

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Ben Lacey ◽  
Jonathan Golledge ◽  
Bu B. Yeap ◽  
Sarah Lewington ◽  
Paul E. Norman ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Vascular Disease ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Older Men

scholarly journals Patient Anxiety About Prostate Cancer Independently Predicts Early Initiation of Androgen Deprivation Therapy for Biochemical Cancer Recurrence in Older Men: A Prospective Cohort Study

2009 ◽  
Vol 27 (10) ◽  
pp. 1557-1563 ◽  
Author(s):  
William Dale ◽  
Joshua Hemmerich ◽  
Kathryn Bylow ◽  
Supriya Mohile ◽  
Mary Mullaney ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cohort Study ◽  
Androgen Deprivation Therapy ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Older Patients ◽  
Older Men ◽  
Androgen Deprivation ◽  
Early Initiation ◽  
Optimal Timing

Purpose Androgen deprivation therapy (ADT) is first-line therapy for patients with prostate cancer (PCA) who experience biochemical recurrence (BCR). However, the optimal timing of ADT initiation is uncertain, and earlier ADT initiation can cause toxicities that lower quality of life (QOL). We tested the hypothesis that elevated cancer anxiety leads to earlier ADT initiation for BCR in older men. Patients and Methods We conducted a prospective cohort study of older patients with BCR of PCA (n = 67). Patients completed questionnaires at presentation and each follow-up visit until initiation of ADT. PCA-specific anxiety was measured with the Memorial Anxiety Scale for Prostate Cancer (MAX-PC). Other collected data included demographics, clinical information, and general anxiety information. Treating oncologists were surveyed about their recommendations for ADT initiation. The primary outcome was the time to ADT initiation. Univariate, multivariate logistic regression, and time-to-event analyses were conducted to evaluate whether cancer anxiety was a predictor of earlier initiation of ADT. Results Thirty-three percent of patients initiated ADT at the first or second clinic visit. Elevated PCA anxiety (MAX-PC > 16) was the most robust predictor in multivariate analyses of early initiation (odds ratio [OR], 9.19; P = .01). PSA also independently correlated with early initiation (OR, 1.31; P = .01). PSA did not correlate with MAX-PC. Conclusion Cancer anxiety independently and robustly predicts earlier ADT initiation in older men with BCR. For older patients with PCA, earlier ADT initiation may not change life expectancy and can negatively impact QOL. PCA-specific anxiety is a potential target for a decision-making intervention in this setting.

scholarly journals Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population

2020 ◽  
Author(s):  
George David Batty ◽  
Ian Deary ◽  
Michelle Luciano ◽  
Drew Altschul ◽  
Mika Kivimaki ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cognitive Function ◽  
Psychosocial Factors ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Area Deprivation ◽  
P Value ◽  
Numerical Reasoning ◽  
Statistical Adjustment ◽  
And Performance

Objective: To examine the association of a range of psychosocial factors with hospitalisation for COVID-19. Design: Prospective cohort study. Setting: England. Participants: UK Biobank comprises around half a million people who were aged 40 to 69 years at study induction between 2006 and 2010 when information on psychosocial factors and covariates were captured. Main outcome measure: Hospitalisation for COVID-19 in England between 16th March and 26th April 2020 as provided by Public Health England. Results: There were 908 hospitalisations for COVID-19 in an analytical sample of 431,051 people. In age- and sex-adjusted analyses, an elevated risk of COVID-19 was related to disadvantaged levels of education (odds ratio; 95% confidence interval: 2.05; 1.70, 2.47), income (2.00; 1.63, 2,47), area deprivation (2.20; 1.86, 2.59), occupation (1.39; 1.14, 1.69), psychological distress (1.58; 1.32, 1.89), mental health (1.50; 1.25, 1.79), neuroticism (1.19; 1.00, 1.42), and performance on two tests of cognitive function: verbal and numerical reasoning (2.66; 2.06, 3.34) and reaction speed (1.27; 1.08, 1.51). These associations were graded (p-value for trend <=0.038) such that effects were apparent across the full psychosocial continua. After mutual adjustment for these characteristics plus ethnicity, comorbidity, and lifestyle factors, only the relationship between lower cognitive function as measured using the reasoning test and a doubling in the risk of the infection remained (1.98; 1.38, 2.85). Conclusion: A range of psychosocial factors revealed associations with hospitalisations for COVID-19 of which the relation with cognitive function was most robust to statistical adjustment.

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