scholarly journals Progress in genome sequencing will accelerate molecular breeding in cotton (Gossypium spp.)

3 Biotech ◽  
2016 ◽  
Vol 6 (2) ◽  
Author(s):  
Rong Yan ◽  
Chengzhen Liang ◽  
Zhigang Meng ◽  
Waqas Malik ◽  
Tao Zhu ◽  
...  
Keyword(s):  
Genome Sequencing ◽  
Molecular Breeding ◽  
Gossypium Spp

Molecular Breeding for Genetic Improvement of Cotton (Gossypium spp.)

2015 ◽  
pp. 613-645 ◽  
Author(s):  
N. Manikanda Boopathi ◽  
Selvam Sathish ◽  
Ponnaikoundar Kavitha ◽  
Ponnusami Dachinamoorthy ◽  
Rajasekar Ravikesavan
Keyword(s):  
Genetic Improvement ◽  
Molecular Breeding ◽  
Gossypium Spp

scholarly journals Whole Genome Sequencing of the Giant Grouper (Epinephelus lanceolatus) and High-Throughput Screening of Putative Antimicrobial Peptide Genes

Marine Drugs ◽  
2019 ◽  
Vol 17 (9) ◽  
pp. 503 ◽  
Author(s):  
Dengdong Wang ◽  
Xiyang Chen ◽  
Xinhui Zhang ◽  
Jia Li ◽  
Yunhai Yi ◽  
...  
Keyword(s):  
Immune Responses ◽  
Antimicrobial Peptide ◽  
Genome Sequencing ◽  
High Throughput Screening ◽  
Molecular Breeding ◽  
Transcriptome Data ◽  
Illumina Hiseq ◽  
Marine Aquaculture ◽  
Adaptive Immune ◽  
High Quality Genome

Giant groupers, the largest grouper type in the world, are of economic importance in marine aquaculture for their rapid growth. At the same time, bacterial and viral diseases have become the main threats to the grouper industry. Here, we report a high-quality genome of a giant grouper sequenced by an Illumina HiSeq X-Ten and PacBio Bioscience Sequel platform. A total of 254 putative antimicrobial peptide (AMP) genes were identified, which can be divided into 34 classes according to the annotation of the Antimicrobial Peptides Database (APD3). Their locations in pseudochromosomes were also determined. Thrombin-, lectin-, and scolopendin-derived putative AMPs were the three largest parts. In addition, expressions of putative AMPs were measured by our transcriptome data. Two putative AMP genes (gapdh1 and gapdh2) were involved in glycolysis, which had extremely high expression levels in giant grouper muscle. As it has been reported that AMPs inhibit the growth of a broad spectrum of microbes and participate in regulating innate and adaptive immune responses, genome sequencing of this study provides a comprehensive cataloging of putative AMPs of groupers, supporting antimicrobial research and aquaculture therapy. These genomic resources will be beneficial to further molecular breeding of this economically important fish.

A chemical genetic roadmap to improved tomato flavor

Science ◽  
2017 ◽  
Vol 355 (6323) ◽  
pp. 391-394 ◽  
Author(s):  
Denise Tieman ◽  
Guangtao Zhu ◽  
Marcio F. R. Resende ◽  
Tao Lin ◽  
Cuong Nguyen ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Sequencing ◽  
Molecular Breeding ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Whole Genome ◽  
Chemical Genetic ◽  
Genome Wide ◽  
A Genome ◽  
Wild Accessions

Modern commercial tomato varieties are substantially less flavorful than heirloom varieties. To understand and ultimately correct this deficiency, we quantified flavor-associated chemicals in 398 modern, heirloom, and wild accessions. A subset of these accessions was evaluated in consumer panels, identifying the chemicals that made the most important contributions to flavor and consumer liking. We found that modern commercial varieties contain significantly lower amounts of many of these important flavor chemicals than older varieties. Whole-genome sequencing and a genome-wide association study permitted identification of genetic loci that affect most of the target flavor chemicals, including sugars, acids, and volatiles. Together, these results provide an understanding of the flavor deficiencies in modern commercial varieties and the information necessary for the recovery of good flavor through molecular breeding.

Genome Sequencing Set to Hunt for Alzheimer's Clues

2012 ◽  
Vol 45 (13) ◽  
pp. 36
Author(s):  
MICHELE G. SULLIVAN
Keyword(s):  
Genome Sequencing

Utility of Whole Genome Sequencing in diagnosing complex disorders: lesson from renal tubular disorders

2018 ◽  
Author(s):  
Mark Stevenson ◽  
Alistair T Pagnamenta ◽  
Heather G Mack ◽  
Judith A Savige ◽  
Kate E Lines ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Whole Genome ◽  
Complex Disorders ◽  
Tubular Disorders ◽  
Renal Tubular Disorders ◽  
Renal Tubular
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