Inhibitor of growth-4 is a potential target for cancer therapy

Tumor Biology ◽  
2016 ◽  
Vol 37 (4) ◽  
pp. 4275-4279 ◽  
Author(s):  
Shuping Yuan ◽  
Jianhua Jin ◽  
Juanjuan Shi ◽  
Yongzhong Hou
Keyword(s):  
Cancer Therapy ◽  
Potential Target

The Urokinase Receptor as a Potential Target in Cancer Therapy

2004 ◽  
Vol 10 (19) ◽  
pp. 2359-2376 ◽  
Author(s):  
John Romer ◽  
Boye Nielsen ◽  
Michael Ploug
Keyword(s):  
Cancer Therapy ◽  
Urokinase Receptor ◽  
Potential Target

Invadopodia: A potential target for pancreatic cancer therapy

2021 ◽  
Vol 159 ◽  
pp. 103236
Author(s):  
Yan Luo ◽  
Jisheng Hu ◽  
Yong Liu ◽  
Le Li ◽  
Yilong Li ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Therapy ◽  
Potential Target ◽  
Pancreatic Cancer Therapy

Nectin cell adhesion molecule-4 (NECTIN-4): A potential target for cancer therapy

2021 ◽  
Vol 911 ◽  
pp. 174516
Author(s):  
Subhajit Chatterjee ◽  
Saptarshi Sinha ◽  
Chanakya Nath Kundu
Keyword(s):  
Cell Adhesion ◽  
Cancer Therapy ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Potential Target

Cholesterol: A Potential Target for Intervention in Anti-Cancer Therapy

2021 ◽  
pp. 154-201
Author(s):  
Nimai Chand Chandra ◽  
Amar Preet Kaur ◽  
Ayantika Talukdar ◽  
Nimisha Saxena ◽  
Shrimanjunath Sankanagoudar
Keyword(s):  
Cancer Therapy ◽  
Potential Target ◽  
Anti Cancer

scholarly journals CDK12: A Potent Target and Biomarker for Human Cancer Therapy

Cells ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 1483 ◽  
Author(s):  
Shujing Liang ◽  
Lifang Hu ◽  
Zixiang Wu ◽  
Zhihao Chen ◽  
Shuyu Liu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cancer Therapy ◽  
Gene Transcription ◽  
Rna Splicing ◽  
Cell Cycle Progression ◽  
Current Knowledge ◽  
Human Cancer ◽  
Cellular Processes ◽  
Potential Target ◽  
Human Cancers

Cyclin-dependent kinases (CDKs) are a group of serine/threonine protein kinases and play crucial roles in various cellular processes by regulating cell cycle and gene transcription. Cyclin-dependent kinase 12 (CDK12) is an important transcription-associated CDK. It shows versatile roles in regulating gene transcription, RNA splicing, translation, DNA damage response (DDR), cell cycle progression and cell proliferation. Recently, increasing evidence demonstrates the important role of CDK12 in various human cancers, illustrating it as both a biomarker of cancer and a potential target for cancer therapy. Here, we summarize the current knowledge of CDK12, and review the research advances of CDK12′s biological functions, especially its role in human cancers and as a potential target and biomarker for cancer therapy.

Sign in / Sign up

Export Citation Format

Share Document