Hyaluronic acid-grafted PLGA nanoparticles for the sustained delivery of berberine chloride for an efficient suppression of Ehrlich ascites tumors

2018 ◽  
Vol 8 (3) ◽  
pp. 565-579 ◽  
Author(s):  
Priyanka Bhatnagar ◽  
Manisha Kumari ◽  
Richa Pahuja ◽  
A. B. Pant ◽  
Y. Shukla ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Plga Nanoparticles ◽  
Sustained Delivery ◽  
Berberine Chloride ◽  
Efficient Suppression ◽  
Ehrlich Ascites ◽  
Ascites Tumors

Die Beeinflussung des Wachstums des Ehrlich-Ascites-Tumors der Maus durch native und mit ultraviolettem Licht bestrahlte heterologe Desoxyribonucleinsäure

1963 ◽  
Vol 18 (7) ◽  
pp. 523-525 ◽  
Author(s):  
Rudolf K. Zahn ◽  
Ekkehard Tiesler
Keyword(s):  
Tumor Growth ◽  
Uv Irradiation ◽  
Deoxyribonucleic Acid ◽  
Tumor Development ◽  
Ehrlich Ascites Tumor ◽  
Ascites Tumor ◽  
Ehrlich Ascites ◽  
Ascites Tumors ◽  
Deoxyribonuclease Activity

1. Deoxyribonuclease activity has been determined by viscosimetry in the serum of the Ehrlich Ascites in the mouse to be equivalent to 2,3 ± 0,7·10-6 g/ml of crystalline beef pancreas DNase.2. Injections of heterologous deoxyribonucleic acid into the Ehrlich Ascites tumor under specified conditions does not alter tumor development.3. The same DNA however becomes strongly inhibitory for tumor growth after UV irradiation.4. Possible implications are discussed.

Amphiphilic hyaluronic acid derivatives toward the design of micelles for the sustained delivery of hydrophobic drugs

2014 ◽  
Vol 102 ◽  
pp. 110-116 ◽  
Author(s):  
Laura Mayol ◽  
Marco Biondi ◽  
Luisa Russo ◽  
Birgitte M. Malle ◽  
Khadija Schwach-Abdellaoui ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Sustained Delivery ◽  
Hydrophobic Drugs

scholarly journals Long-Term Treatment with Aqueous Garlic and/or Tomato Suspensions Decreases Ehrlich Ascites Tumors

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Jenifer Bom ◽  
Patrícia Gunutzmann ◽  
Elizabeth C. Pérez Hurtado ◽  
Jussara M. R. Maragno-Correa ◽  
Silvia Regina Kleeb ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Term Treatment ◽  
Therapeutic Effects ◽  
Short Term ◽  
Volume Number ◽  
Aqueous Suspensions ◽  
Ehrlich Ascites ◽  
Long Term Treatment ◽  
Ascites Tumors

We evaluated the preventive and therapeutic effects of aqueous suspensions of garlic, tomato, and garlic + tomato in the development of experimental Ehrlich tumors in mice. The aqueous suspensions (2%) were administered over a short term for 30 days before tumor inoculation and 12 days afterward, and suspensions at 6% were administered for 180 days before inoculation and for 12 days afterward. The volume, number, and characteristics of the tumor cells and AgNOR counts were determined to compare the different treatments. Aqueous 6% suspensions of garlic, tomato, and garlic + tomato given over the long term significantly reduced tumor growth but when given over the short term, they did not alter tumor growth.

TUMOR CELL POPULATION OF THE EHRLICH ASCITES TUMORS

1968 ◽  
Vol 10 (3) ◽  
pp. 723-746 ◽  
Author(s):  
Narsingh D. Agnish ◽  
Sergey Fedoroff
Keyword(s):  
Tumor Cell ◽  
Cell Population ◽  
Tumor Cell Population ◽  
Ehrlich Ascites ◽  
Ascites Tumors

scholarly journals Transdermal patches fabricated from hyaluronic acid for the enhanced skin penetration of therapeutic entities

2019 ◽  
Vol 9 (1) ◽  
pp. 252-256
Author(s):  
Syam S. Nair
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Transdermal Drug Delivery ◽  
Skin Penetration ◽  
Sustained Delivery ◽  
Research Groups ◽  
Outermost Layer ◽  
Drug Molecules ◽  
Different Types ◽  
Transdermal Route

Skin is an attractive route for drug delivery. However poor permeation of drugs across the skin due to the presence of extremely ordered architecture of outermost layer of skin, led to several investigation to improve the permeability of drugs. Polysaccharides remain widely studied biomaterial for the sustained delivery of drug molecules across the skin. The advance of hyaluronic acid (HA) chemistry with multiple benefits has improved the attention of research groups for its application in the skin transportation of drug molecules. Beginning from the advantages of transdermal route, the present review details the application of HA in transdermal drug delivery. In the last few decades, substantial investigation in the domain has improved the requirement for an outline of all the developments, which is depicted in the review. The review also presented different types of HA based transdermal devices such as transferosomes, nanoemulsions, microneedle etc and their potential to improve the transdermal drug delivery. Furthermore the application of HA through chemical modification as a potential transdermal device is also presented. Keywords: Hyaluronic acid, transdermal drug delivery, microneedles, nanoemulsion, hydrogel

Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound via anti-inflammation and enhanced cell proliferation and angiogenesis

Nanoscale ◽  
2022 ◽  
Author(s):  
Lin-yu Long ◽  
Wenqi Liu ◽  
Li Li ◽  
Cheng Hu ◽  
Shuyi He ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Hyaluronic Acid ◽  
Glycolic Acid ◽  
Chronic Wounds ◽  
Collagen Type ◽  
Chronic Wound ◽  
Plga Nanoparticles ◽  
Collagen Type Iii ◽  
Type Iii ◽  
Anti Inflammation

The first recombinant humanized collagen type III (rhCol III) and naproxen (Nap) loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles incorporated hyaluronic acid (HA) microneedle (MN) was fabricated for diabetic chronic wounds therapy.

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