scholarly journals Exercise in Obesity—the Role of Technology in Health Services: Can This Approach Work?

Author(s):  
Laurence J. Dobbie ◽  
Abd Tahrani ◽  
Uazman Alam ◽  
Jennifer James ◽  
John Wilding ◽  
...  

Abstract Purpose of Review Physical activity (PA) is an important strategy to prevent and treat obesity. Electronic health (eHealth) interventions, such as wearable activity monitors and smartphone apps, may promote adherence to regular PA and successful weight loss. This review highlights the evidence for eHealth interventions in promoting PA and reducing weight. Recent Findings Wearables can increase PA and are associated with moderate weight loss in middle/older-aged individuals, with less convincing effects long-term (> 1 year) and in younger people. Data for interventions such as mobile phone applications, SMS, and exergaming are less robust. Investigations of all eHealth interventions are often limited by complex, multi-modality study designs, involving concomitant dietary modification, making the independent contribution of each eHealth intervention on body weight challenging to assess. Summary eHealth interventions may promote PA, thereby contributing to weight loss/weight maintenance; however, further evaluation is required for this approach to be adopted into routine clinical practice.

2016 ◽  
Vol 174 (6) ◽  
pp. 775-784 ◽  
Author(s):  
Eva W Iepsen ◽  
Julie Lundgren ◽  
Jens J Holst ◽  
Sten Madsbad ◽  
Signe S Torekov

ObjectiveThe hormones glucagon-like peptide 1 (GLP-1), peptide YY3-36(PYY3–36), ghrelin, glucose-dependent insulinotropic polypeptide (GIP) and glucagon have all been implicated in the pathogenesis of obesity. However, it is unknown whether they exhibit adaptive changes with respect to postprandial secretion to a sustained weight loss.DesignThe study was designed as a longitudinal prospective intervention study with data obtained at baseline, after 8 weeks of weight loss and 1 year after weight loss.MethodsTwenty healthy obese individuals obtained a 13% weight loss by adhering to an 8-week very low-calorie diet (800kcal/day). After weight loss, participants entered a 52-week weight maintenance protocol. Plasma levels of GLP-1, PYY3–36, ghrelin, GIP and glucagon during a 600-kcal meal were measured before weight loss, after weight loss and after 1 year of weight maintenance. Area under the curve (AUC) was calculated as total AUC (tAUC) and incremental AUC (iAUC).ResultsWeight loss was successfully maintained for 52 weeks. iAUC for GLP-1 increased by 44% after weight loss (P<0.04) and increased to 72% at week 52 (P=0.0001). iAUC for PYY3–36increased by 74% after weight loss (P<0.0001) and by 36% at week 52 (P=0.02). tAUC for ghrelin increased by 23% after weight loss (P<0.0001), but at week 52, the increase was reduced to 16% compared with before weight loss (P=0.005). iAUC for GIP increased by 36% after weight loss (P=0.001), but returned to before weight loss levels at week 52. Glucagon levels were unaffected by weight loss.ConclusionsMeal responses of GLP-1 and PYY3–36remained increased 1 year after weight maintenance, whereas ghrelin and GIP reverted toward before-weight loss values. Thus, an increase in appetite inhibitory mechanisms and a partly decrease in appetite-stimulating mechanisms appear to contribute to successful long-term weight loss maintenance.


2020 ◽  
Vol 74 (7) ◽  
pp. 1115-1116
Author(s):  
George Thom ◽  
Stephan U. Dombrowski ◽  
Naomi Brosnahan ◽  
Yasmin Y. Algindan ◽  
M. Rosario Lopez-Gonzalez ◽  
...  

Circulation ◽  
2011 ◽  
Vol 124 (25) ◽  
pp. 2829-2838 ◽  
Author(s):  
Özlem Gögebakan ◽  
Angela Kohl ◽  
Martin A. Osterhoff ◽  
Marleen A. van Baak ◽  
Susan A. Jebb ◽  
...  

2015 ◽  
Vol 1 (3) ◽  
pp. 1-14
Author(s):  
Volker Schusdziarra ◽  
Margit Hausmann ◽  
Raphaela Prester ◽  
Stefan Wagenpfeil ◽  
Jürgen W. Bauer ◽  
...  

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