Cardiac Autonomic Modulation in Response to Three Types of Exercise in Patients with Type 2 Diabetic Neuropathy

Author(s):  
Elaheh Piralaiy ◽  
Marefat Siahkuhian ◽  
Saeed Dabbagh Nikookheslat ◽  
Linda S. Pescatello ◽  
Mahboub Sheikhalizadeh ◽  
...  
2005 ◽  
Vol 21 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Chun-Chiang Huang ◽  
Chia-Ling Lee ◽  
Mao-Hsiung Huang ◽  
Tien-Wen Chen ◽  
Ming-Cheng Weng ◽  
...  

Diabetes Care ◽  
2015 ◽  
pp. dc140654 ◽  
Author(s):  
Jesper Fleischer ◽  
Simon Lebech Cichosz ◽  
Pernille Hoeyem ◽  
Esben Laugesen ◽  
Per Loegstrup Poulsen ◽  
...  

Diabetes is a growing global problem that is currently on the rise. Type 2 diabetes (T2D) is a chronic condition that results from aberrant B-cell function coupled with progressive insulin resistance. The majority of Type 2 diabetic patients develop diabetic neuropathy, which can lead to devastating complications (i.e., infection, ulceration, osteomyelitis, & amputation). The proinflammatory state of diabetes, along with prolonged hyperglycemia damages peripheral nerves (most common in the lower extremities). Additionally, compromised wound healing exacerbates the risk when skin breakdown occurs in this patient population. To overcome these risks for T2D, physiologic insulin resensitization (PIR) has been used as a novel protocol to treat patients with severe neuropathy symptoms. In our case study, we present two patients who initially experienced a loss of sensation in their extremities and decreased wound healing. Using PIR treatment, we demonstrate that both patients experienced neuropathy reversal and improved wound healing.


Author(s):  
Michael J. Macartney ◽  
Sean R. Notley ◽  
Christophe Herry ◽  
Ronald J Sigal ◽  
Pierre Boulay ◽  
...  

The effects of exercise-heat acclimation (HA), in individuals with type 2 diabetes (T2D), on heart rate variability (HRV) remains unclear. We assessed electrocardiogram recordings during exercise-heat stress, in middle-aged-to-older individuals (50-70 years) with (n=6) and without (n=8; CON) T2D, before and after 7-days exercise HA. Exercising heart rate was reduced (CON, -9 ±5 bpm; T2D, -14 ±9 bpm) yet HRV was unresponsive. Given the negative correlations between diminished HRV and cardiac risk, further research is warranted. <b>Novelty bullet point:</b> Our observations indicate that exercise-heat acclimation may not effectively attenuate the deviation toward reduced overall HRV and unfavourable cardiac autonomic modulation in individuals with T2D.


2008 ◽  
Vol 9 (1) ◽  
pp. 109
Author(s):  
S.A. Manea ◽  
A. Constantinescu ◽  
C. Heltianu

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