Pediatric musculoskeletal ultrasound: a pictorial essay

Background: Rheumatoid arthritis (RA) is a common progressive chronic inflammatory autoimmune disease which affects mostly small joints, causing pain, swelling, deformity, and disability. Although progress has been made in exploring RA nature, still there is a lot to know about the disease pathogenesis, diagnosis, and treatment. Aim of the Work: To investigate the role of serum anti-carbamylated protein antibodies and 14-3-3η in the diagnosis of RA compared to rheumatoid factor (RF), anti-CCP antibodies, and highfrequency musculoskeletal ultrasound used to assess the disease activity and joint damage. Methods: Serum anti-carbamylated protein antibodies and 14-3-3η were measured using ELISA in 61 RA patients and 26 normal controls. RA Disease Activity Score (DAS 28), X-ray and musculoskeletal ultrasound (hands and feet), carotid ultrasound (Intima-Media Thickness IMT) were used in assessing the RA disease. Results: Anti-carbamylated protein antibodies were significantly elevated in RA patients 4.5 (4.1- 8.9 U⁄ml) compared to the control 3.2(1.9- 4.3 U⁄ml) (p< 0.001) but 14-3-3η showed no significant difference. There was a significant positive correlation between anti-carbamylated protein antibodies, 14-3-3η levels and disease activity score assessed by DAS 28, increased IMT measured by carotid duplex, total synovitis and total erosion score were assessed by musculoskeletal ultrasound. There was no correlation between RF and anti-CCP antibodies. Anti-carbamylated protein antibodies were found to have 66.7% sensitivity and 85.2% specificity in RA diagnosis, while 14- 3-3η had 51.9% sensitivity and 72.1% specificity. Conclusion: Anti-carbamylated protein antibodies and 14-3-3η have a high sensitivity and specificity in RA diagnosis and had a correlation with the disease activity and joint damage.

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Upper Arm Central Venous Port Implantation: A 6-Year Single Institutional Retrospective Analysis and Pictorial Essay of Procedures for Insertion

PLoS ONE ◽

10.1371/journal.pone.0091335 ◽

2014 ◽

Vol 9 (3) ◽

pp. e91335 ◽

Cited By ~ 13

Author(s):

Masatoshi Shiono ◽

Shin Takahashi ◽

Yuichi Kakudo ◽

Masanobu Takahashi ◽

Hideki Shimodaira ◽

...

Keyword(s):

Retrospective Analysis ◽

Central Venous ◽

Upper Arm ◽

Central Venous Port ◽

Venous Port ◽

Port Implantation ◽

Pictorial Essay

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Sonography of perinephric fluid collections: A pictorial essay

Journal of Clinical Ultrasound ◽

10.1002/jcu.22680 ◽

2019 ◽

Vol 47 (3) ◽

pp. 150-160 ◽

Cited By ~ 1

Author(s):

Teng-Fu Tsao ◽

Keng-Wei Liang ◽

Hsin-Hui Huang ◽

Yeu-Sheng Tyan ◽

Yu-Hua Chao

Keyword(s):

Pictorial Essay ◽

Fluid Collections

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Complications in Idiopathic Pulmonary Fibrosis: Focus on Their Clinical and Radiological Features

Diagnostics ◽

10.3390/diagnostics10070450 ◽

2020 ◽

Vol 10 (7) ◽

pp. 450

Author(s):

Federica Galioto ◽

Stefano Palmucci ◽

Giovanna M. Astuti ◽

Ada Vancheri ◽

Giulio Distefano ◽

...

Keyword(s):

Idiopathic Pulmonary Fibrosis ◽

Pulmonary Fibrosis ◽

Lung Disease ◽

Integrated Approach ◽

Correct Treatment ◽

Radiological Features ◽

Palliative Care Services ◽

Pictorial Essay ◽

Personalized Approach ◽

Fibrotic Lung Disease

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with uncertain origins and pathogenesis; it represents the most common interstitial lung disease (ILD), associated with a pathological pattern of usual interstitial pneumonitis (UIP). This disease has a poor prognosis, having the most lethal prognosis among ILDs. In fact, the progressive fibrosis related to IPF could lead to the development of complications, such as acute exacerbation, lung cancer, infections, pneumothorax and pulmonary hypertension. Pneumologists, radiologists and pathologists play a key role in the identification of IPF disease, and in the characterization of its complications—which unfortunately increase disease mortality and reduce overall survival. The early identification of these complications is very important, and requires an integrated approach among specialists, in order to plane the correct treatment. In some cases, the degree of severity of patients having IPF complications may require a personalized approach, based on palliative care services. Therefore, in this paper, we have focused on clinical and radiological features of the complications that occurred in our IPF patients, providing a comprehensive and accurate pictorial essay for clinicians, radiologists and surgeons involved in their management.

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SWE and SMI ultrasound techniques for monitoring needling treatment of ankylosing spondylitis: study protocol for a single-blinded randomized controlled trial

Trials ◽

10.1186/s13063-021-05344-z ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Mengyu Wang ◽

Wen Fu ◽

Lingcui Meng ◽

Jia Liu ◽

Lihua Wu ◽

...

Keyword(s):

Quality Of Life ◽

Blood Flow ◽

Ankylosing Spondylitis ◽

Outcome Measures ◽

Healthy Subjects ◽

Acupuncture Group ◽

Musculoskeletal Ultrasound ◽

Sham Control ◽

Post Intervention

Abstract Background Ankylosing spondylitis (AS) is a high-incidence disease in young men that interferes with patients’ physical and mental wellbeing and overall quality of life (QoL). It is often accompanied by arthralgia, stiffness, and limited lumbar flexibility. Acupuncture is safe and effective for reducing the symptoms of AS, but the underlying mechanisms by which it does so are not fully understood. Therefore, to objectively assess acupuncture efficacy, which is critical for patients making informed decisions about appropriate treatments, we will use shear-wave elastography (SWE) and superb microvascular imaging (SMI) ultrasound techniques to evaluate elasticity of lumbar paraspinal muscles and blood flow to the sacroiliac joint (SIJ) in AS. Methods We will recruit a total of 60 participants diagnosed with AS and 30 healthy subjects. Participants will be randomly allocated 1:1 to either an acupuncture group or a sham control acupuncture group. Primary-outcome measures will be musculoskeletal ultrasound, Ankylosing Spondylitis Quality of Life Scale (ASQoL), Bath Ankylosing Spondylitis Metrology Index (BASMI), and the Visual Analogue Scale (VAS) for pain. Secondary outcome measures will be the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Function Index (BASFI), and Fatigue Scale-14 (FS-14). We will monitor the effect of acupuncture or sham acupuncture on blood flow and SIJ inflammation using SMI, lumbar-muscle stiffness using SWE and the lumbar paraspinal-muscle cross-sectional area (CSA) using a two-dimensional (2D) grayscale imaging. QoL, physical function, and fatigue will be assessed using an evaluation scale or questionnaire developed for this study, with outcomes measured by the ASQoL, BASMI, BASDAI, BASFI, and FS-14. Healthy subjects will not receive acupuncture but undergo only musculoskeletal ultrasound at baseline. Acupuncture and sham control acupuncture interventions will be conducted for 30 min, 2–3 times/week for 12 weeks. Musculoskeletal ultrasound will be conducted at baseline and post-intervention, while other outcomes will be measured at baseline, 6 weeks, and post-intervention. The statistician, outcome assessor, and participants will be blinded to treatment allocation. Discussion The results of this single-blinded, randomized trial with sham controls could help demonstrate the efficacy of acupuncture and clarify whether musculoskeletal ultrasound could be used to evaluate AS. Trial registration ClinicalTrials.gov ChiCTR2000031476. Registered 3 April 2020.

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Pictorial essay: How co-registered BOLD fMRI and DTI data can improve diffusion tensor tractography

Interdisciplinary Neurosurgery ◽

10.1016/j.inat.2021.101258 ◽

2021 ◽

pp. 101258

Author(s):

Bojan D. Petrovic ◽

Doug Burman ◽

Shakeel Chowdhry ◽

Julian E. Bailes ◽

Joel Meyer

Keyword(s):

Diffusion Tensor ◽

Diffusion Tensor Tractography ◽

Bold Fmri ◽

Pictorial Essay

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