Kidney transplantation after peritoneal dialysis-associated peritonitis and abdominal abscesses caused by Mycobacterium massiliense: lesson for the clinical nephrologist

Author(s):  
Yasuhiro Ueda ◽  
Takayuki Okamoto ◽  
Yasuyuki Sato ◽  
Asako Hayashi ◽  
Toshiyuki Takahashi ◽  
...  
1994 ◽  
Vol 23 (5) ◽  
pp. 717-721 ◽  
Author(s):  
Hassan Boroujerdi-Rad ◽  
Peter Juergensen ◽  
Vazrick Mansourian ◽  
Alan S. Kliger ◽  
Fredric O. Finkelstein

2018 ◽  
Vol 143 (12) ◽  
pp. 863-870
Author(s):  
Jan Galle ◽  
Jana Reitlinger

AbstractIn renal replacement therapy, different methods are available: hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KTx). In addition, variants can be used: HD as a home HD or center HD, PD as a conventional PD or automated (cycler) PD, KTx as a potentially short-term predictable living donation or conventional donor kidney donation. The patient and his familiar or caring environment must be informed accordingly. This means first of all: information about which procedures of kidney replacement therapy are possible and can be offered. Then the specific risks associated with each procedure should be elucidated (e. g. HD and shunt bleeding, PD and peritonitis, KTx and infections/neoplasias). This necessarily includes a structured documentation of the educating center/doctor about the communicated information and decisions taken.


2020 ◽  
Vol 2020 ◽  
pp. 1-20 ◽  
Author(s):  
Graziano Colombo ◽  
Francesco Reggiani ◽  
Claudio Angelini ◽  
Silvia Finazzi ◽  
Emanuela Astori ◽  
...  

Accumulating evidence indicates that oxidative stress plays a role in the pathophysiology of chronic kidney disease (CKD) and its progression; during renal replacement therapy, oxidative stress-derived oxidative damage also contributes to the development of CKD systemic complications, such as cardiovascular disease, hypertension, atherosclerosis, inflammation, anaemia, and impaired host defence. The main mechanism underlying these events is the retention of uremic toxins, which act as a substrate for oxidative processes and elicit the activation of inflammatory pathways targeting endothelial and immune cells. Due to the growing worldwide spread of CKD, there is an overwhelming need to find oxidative damage biomarkers that are easy to measure in biological fluids of subjects with CKD and patients undergoing renal replacement therapy (haemodialysis, peritoneal dialysis, and kidney transplantation), in order to overcome limitations of invasive monitoring of CKD progression. Several studies investigated biomarkers of protein oxidative damage in CKD, including plasma protein carbonyls (PCO), the most frequently used biomarker of protein damage. This review provides an up-to-date overview on advances concerning the correlation between plasma protein carbonylation in CKD progression (from stage 1 to stage 5) and the possibility that haemodialysis, peritoneal dialysis, and kidney transplantation improve plasma PCO levels. Despite the fact that the role of plasma PCO in CKD is often underestimated in clinical practice, emerging evidence highlights that plasma PCO can serve as good biomarkers of oxidative stress in CKD and substitutive therapies. Whether plasma PCO levels merely serve as biomarkers of CKD-related oxidative stress or whether they are associated with the pathogenesis of CKD complications deserves further evaluation.


PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227870
Author(s):  
Laurisson Albuquerque da Costa ◽  
Maria Cláudia Cruz Andreoli ◽  
Aluizio Barbosa Carvalho ◽  
Sérgio Antonio Draibe ◽  
José Osmar Medina Pestana ◽  
...  

2014 ◽  
Vol 34 (4) ◽  
pp. 443-446 ◽  
Author(s):  
Mohammad-Hadi Saeed Modaghegh ◽  
Gholamhossein Kazemzadeh ◽  
Yaser Rajabnejad ◽  
Fatemeh Nazemian

IntroductionThis study describes a new preperitoneal tunneling (PPT) method for inserting a peritoneal dialysis catheter (PDC), thereby lessening surgical complications and increasing the catheter's survival.MethodsThis new technique was used in 23 cases from December 2005 to January 2007 and followed up until March 2011 (63 months). The procedure was performed laparoscopically under local (16 cases) or general (7 cases) anesthesia by one surgeon. Catheter survival is reported by Kaplan-Meyer analysis.ResultsThe catheters were mechanically obstructed in 2/23 cases (8.7%); and were withdrawn due to a peritonitis in 2 cases and inadequacy of peritoneal dialysis in 1 case. Ten patients received kidney transplantation and six died before completing this follow-up period. The patients still reaped the benefits of the PDC until receiving a kidney transplant or death. The 5-year survival rate of the catheter was 89%. No incidence of catheter migration, omental wrapping, herniation or leakage was noticed.ConclusionPreperitoneal tunneling is a simple and safe method for insertion of PDC, and can effectively prevent catheter migration, dislocation and omental wrapping.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Adoración Martinez ◽  
Manuel Lanuza ◽  
Diana Manzano ◽  
Francisca Lopez ◽  
Eulalia Carceles ◽  
...  

Abstract Background and Aims Simultaneous pancreas-Kidney transplantation (SPKT) has established its position in treating patients with type 1diabetes and end-stage renal disease. Infections in the early post-transplantation period are one of the most significant causes of the high morbidity and mortality rates associated with SPKT. Pre-transplant dialysis modality may affect evolution and it has suspected that peritoneal dialysis (PD) is associated whit more surgical complications, especially intra-abdominal infections. The aim: evaluate whether pretransplant dialysis modality affects the risk for postoperative complications in SPKT transplant recipients Method retrospective and descriptive study of a series of patients who underwent SPKT from 2000 to 2018 in our hospital. We studied complication occurring during the first 3 months after transplantation Results From 2000 to 2019 we performed 38 SPKT in 22 men and 16 women. The mean age of the patients was 35.3(28-44) years. Of the 38 SPKT patients, 44.7% on hemodialysis before transplantation, 26.3% were on peritoneal dialysis and 28.9% had not received any substitutive renal therapy. Were similar regarding baseline characteristics. The complications of the post-transplant period are shown in graph 1. The most frequent complications were infectious in almost 2/3 of the patients and within them the intra-abdominal infections affected almost half, 18, of the patients. Were 3 thrombosis of the pancreas that caused the loss of the graft but none of the kidney. All early postoperative complications are compared in table 1.Whit no significant difference between groups of intraabdominal infection (p. 0.5) and graft thrombosis (p 0.7). There were also no differences in relaparotomy, acute rejection and delayed graft function During the follow-up 4 patients died, one case due to a heart attack while the other 3 in relation to intraabdominal infectious processes and need for reintervention Conclusion: Despite improvements in the outcomes of STKP infectious complications remain a significant cause of morbidity and mortality Peritoneal dialysis is not a risk factor postoperative complication after STPK


2018 ◽  
Vol 19 (2) ◽  
pp. 172-176 ◽  
Author(s):  
Dinesh Bansal ◽  
Vijay Kher ◽  
Krishan Lal Gupta ◽  
Debasish Banerjee ◽  
Vivekanand Jha

Introduction: Despite the growing number of haemodialysis (HD) patients in India, little is known about vascular access practice. We investigated the use and cost of different vascular accesses by Indian nephrologists. Methods: An online survey was emailed to 920 Indian nephrologists and 388 (42.1%) responded; 98.5% of whom were responsible for managing dialysis patients, 98% in hospitals. Results: Sixty-four percent of patients initiated renal replacement therapy with HD, 7% with peritoneal dialysis, 10% kidney transplantation and 19% conservative care. Forty-eight percent of patients were self-paying, 26% had employee reimbursement and 23% had insurance. According to 59% of responders, more than three-quarters of patients started dialysis with uncuffed catheter, less than one-quarter started dialysis with fistula; and very few used grafts or tunnelled catheters. Among prevalent HD patients, over half were dialysing with fistula (79% nephrologists), rather than uncuffed catheters (15% nephrologists) or grafts (<1% nephrologists). Sixteen percent reported at least one catheter-related sepsis in more than half of patients. Placement of uncuffed catheters cost US$160 in 92% facilities, whereas tunnelled catheters cost US$320 in 46% of facilities. An arteriovenous fistula (AVF) could be created for US$160 in 40%, and US$320 in 90% of centres. Thirty-five percent of nephrologists reported that grafts were not placed at their institute and where they were available, the average cost was over US$480. Forty-six percent of nephrologists had access to pre-dialysis clinics, <30% to vascular access programmes, and <17% conducted regular vascular access audits. Conclusions: The survey provides a snapshot of the current status of vascular access care in HD patients and highlights need for pre-dialysis clinics, vascular access services and registry audits.


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