scholarly journals Clinical outcomes of incident peritoneal dialysis patients coming from kidney transplantation program: A case-control study

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227870
Author(s):  
Laurisson Albuquerque da Costa ◽  
Maria Cláudia Cruz Andreoli ◽  
Aluizio Barbosa Carvalho ◽  
Sérgio Antonio Draibe ◽  
José Osmar Medina Pestana ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Kidney Transplantation ◽  
Clinical Outcomes ◽  
Case Control Study ◽  
Case Control ◽  
Dialysis Patients ◽  
Transplantation Program ◽  
Control Study

Long-Term Clinical Outcomes of Lupus Nephritis Patients Undergoing Peritoneal Dialysis: A Matched, Case-Control Study

2019 ◽  
Vol 39 (6) ◽  
pp. 570-573
Author(s):  
Hongjian Ye ◽  
Peiyi Cao ◽  
Jianxiong Lin ◽  
Xiao Yang ◽  
Qunying Guo ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Lupus Nephritis ◽  
Clinical Outcomes ◽  
Case Control Study ◽  
Patient Survival ◽  
Case Control ◽  
Infection Rates ◽  
Technique Failure ◽  
Control Study

The long-term clinical outcomes of peritoneal dialysis (PD) for patients with lupus nephritis (LN) have not been well researched. In the present study, we investigated the long-term prognosis of a Chinese PD cohort. This was a retrospective case-control study that included LN patients receiving PD treatment for more than 90 days from January 2006 to December 2012. Non-diabetic control patients were selected using a ratio of 1:2 for age- and gender-matching. The primary outcome was all-cause mortality. Secondary outcomes included technique failure and hospitalization rate. All patients were followed up to 31 December 2017. A total of 28 LN patients on PD (89.3% female, mean age 42.2±15.8 years) and 56 controls were included. After a median follow-up period of 53.1 months, 11 LN patients died. The cumulative 1-, 3-, and 5-year patient survival rates were 92.4%, 84.7%, and 67.6% in LN patients, and 100%, 93.5%, and 82.9% in the control group, respectively ( p = 0.035). After adjusting for confounders, LN was not significantly associated with mortality (hazard ratio [HR]: 1.39, 95% confidence interval [CI]: 0.45 – 4.26); However, LN was still an independent risk factor of technique failure (HR: 2.87, 95% CI: 1.08 – 7.66). Meanwhile, the LN group had significantly higher hospitalization and infection rates. In conclusion, LN patients undergoing PD had poor patient survival and technique survival, and higher hospitalization and infection rates.

scholarly journals Inguinal hernia in hemodialysis versus peritoneal dialysis patients: a case-control study

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Masataka Banshodani ◽  
Hideki Kawanishi ◽  
Misaki Moriishi ◽  
Sadanori Shintaku ◽  
Shinji Hashimoto ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Inguinal Hernia ◽  
Case Control Study ◽  
Case Control ◽  
Dialysis Patients ◽  
Control Study

scholarly journals Significance of new membrane formation in peritoneal biopsies of peritoneal dialysis patients: a case–control study

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Kazuho Honda ◽  
◽  
Chieko Hamada ◽  
Kunio Kawanishi ◽  
Masaaki Nakayama ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Case Control Study ◽  
Case Control ◽  
Dialysis Patients ◽  
Membrane Formation ◽  
Control Study

Optimization of Expanded Donors Using Dual Kidney Transplantation: Case-control Study

2012 ◽  
Vol 44 (7) ◽  
pp. 2060-2062 ◽  
Author(s):  
M.A. Frutos ◽  
J.J. Mansilla ◽  
M. Cabello ◽  
J. Soler ◽  
P. Ruiz ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Determining the clinical significance of co-colonization of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus in the intestinal tracts of patients in intensive care units: a case–control study

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Young Kyung Yoon ◽  
Min Jung Lee ◽  
Yongguk Ju ◽  
Sung Eun Lee ◽  
Kyung Sook Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Clinical Outcomes ◽  
Intensive Care Units ◽  
Case Control Study ◽  
Case Control ◽  
Methicillin Resistant ◽  
Vancomycin Resistant ◽  
Control Study

Abstract Background The emergence of vancomycin-resistant Staphylococcus aureus (VRSA) has become a global concern for public health. The proximity of vancomycin-resistant enterococcus (VRE) and methicillin-resistant S. aureus (MRSA) is considered to be one of the foremost risk factors for the development of VRSA. This study aimed to determine the incidence, risk factors, and clinical outcomes of intestinal co-colonization with VRE and MRSA. Methods A case–control study was conducted in 52-bed intensive care units (ICUs) of a university-affiliated hospital from September 2012 to October 2017. Active surveillance using rectal cultures for VRE were conducted at ICU admission and on a weekly basis. Weekly surveillance cultures for detection of rectal MRSA were also conducted in patients with VRE carriage. Patients with intestinal co-colonization of VRE and MRSA were compared with randomly selected control patients with VRE colonization alone (1:1). Vancomycin minimum inhibitory concentrations (MICs) for MRSA isolates were determined by the Etest. Results Of the 4679 consecutive patients, 195 cases and 924 controls were detected. The median monthly incidence and duration of intestinal co-colonization with VRE and MRSA were 2.3/1000 patient-days and 7 days, respectively. The frequency of both MRSA infections and mortality attributable to MRSA were higher in the case group than in the control group: 56.9% vs. 44.1% (P = 0.011) and 8.2% vs. 1.0% (P = 0.002), respectively. Independent risk factors for intestinal co-colonization were enteral tube feeding (odds ratio [OR], 2.09; 95% confidence interval [CI] 1.32–3.32), metabolic diseases (OR, 1.75; 95% CI 1.05–2.93), male gender (OR, 1.62; 95% CI 1.06–2.50), and Charlson comorbidity index < 3 (OR, 3.61; 95% CI 1.88–6.94). All MRSA isolates from case patients were susceptible to vancomycin (MIC ≤ 2 mg/L). Conclusions Our study indicates that intestinal co-colonization of VRE and MRSA occurs commonly among patients in the ICU with MRSA endemicity, which might be associated with poor clinical outcomes.

Calcium Use Increases Risk of Calciphylaxis: A Case-Control Study

1999 ◽  
Vol 19 (3) ◽  
pp. 248-252 ◽  
Author(s):  
James M. Zacharias ◽  
Bunny Fontaine ◽  
Adrian Fine
Keyword(s):  
Risk Factor ◽  
Peritoneal Dialysis ◽  
Calcium Carbonate ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Laboratory Data ◽  
Case Control ◽  
Calcium Deposition ◽  
Increased Risk ◽  
Control Study

Objective To investigate the risk factors for the development of calciphylaxis in renal failure, a poorly understood and often fatal condition characterized by calcium deposition in tissues. Design Retrospective case-control study. Setting University hospital peritoneal dialysis center. Patients Eight continuous ambulatory peritoneal dialysis (CAPD) patients with calciphylaxis were identified in a 3-year period. We matched up to five controls for dialysis modality and length of time on dialysis with each case. Statistics Multivariate conditional logistic regression analysis for matched case-controls. Main Outcome Measures Laboratory data and demographics were collected as well as cumulative calcium and vitamin D ingestion over the year prior to disease onset. Results All the patients were female, versus only 38% (14/37) of controls ( p < 0.0001). While not statistically significant, a majority of the patients were diabetic [62.5% (5/8) vs 32% (12/37)]. Peak and average levels of serum calcium, phosphate, calcium x phosphate product, parathyroid hormone (PTH), albumin, iron, total iron-binding capacity (TIBC), and ferritin were not significantly different in cases compared with controls. The use of calcitriol alone or with calcium carbonate was not found to be a significant risk factor for the development of calciphylaxis. In a multivariate analysis, iron intake seemed to be protective, contrary to previous reports, while the use of calcium carbonate was associated with a strong trend to increased risk of calciphylaxis development (odds ratio = 1.029/g and 1.011/g calcium ingested per month, at 1 and 2 – 3 months prior to calciphylaxis development; p = 0.0556 and 0.0565, respectively). Conclusion These data, although limited by the small numbers of index cases, suggest that calcium ingestion is a risk factor for calciphylaxis. The increased use of calcium salts as a phosphate binder in recent years might explain the apparent increased incidence of calciphylaxis in our and other centers. The preponderance of female diabetics among cases reported elsewhere was confirmed in our study.

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