scholarly journals Real-World Use and Outcomes of Oral Antiplatelets Among Patients with Acute Coronary Syndrome: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Samuel K. Peasah ◽  
Douglas Mager ◽  
Kiraat D. Munshi ◽  
Yan Huang ◽  
Rochelle Henderson ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Cohort Study ◽  
Real World ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Coronary Syndrome

scholarly journals Cardiovascular Risk and Acute Coronary Syndrome in Giant Cell Arteritis: A Population-Based Retrospective Cohort Study

2015 ◽  
Vol 67 (3) ◽  
pp. 396-402 ◽  
Author(s):  
Prabhu D. Udayakumar ◽  
Arun K. Chandran ◽  
Cynthia S. Crowson ◽  
Kenneth J. Warrington ◽  
Eric L. Matteson
Keyword(s):  
Acute Coronary Syndrome ◽  
Cohort Study ◽  
Cardiovascular Risk ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Population Based ◽  
Coronary Syndrome

scholarly journals A retrospective cohort study of oral anticoagulant treatment in patients with acute coronary syndrome and atrial fibrillation

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e031180 ◽  
Author(s):  
Linlin Mai ◽  
Yu Wu ◽  
Jianjing Luo ◽  
Xinyue Liu ◽  
Hailan Zhu ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Oral Anticoagulant ◽  
Retrospective Cohort ◽  
Anticoagulant Treatment ◽  
Coronary Syndrome ◽  
Increased Risk ◽  
To Receive

ObjectiveTo examine the real-world patterns of oral anticoagulant (OAC) therapy in patients with acute coronary syndrome (ACS) and atrial fibrillation (AF) in Southern China undergoing percutaneous coronary intervention (PCI) and determine the clinical characteristics associated with OAC prescription.DesignA retrospective cohort study.SettingThis study was conducted in the Shunde Hospital, Southern Medical University and the second hospital of Zhaoqing, China, from January 2013 to 31 December 2018.ParticipantsPatients were aged ≥18 years, hospitalised for ACS and received PCI treatment.Outcome measuresAF was diagnosed based on an ECG recording or a Holter monitor. Prescription of OACs and antiplatelets were determined from the discharge medication list.ResultsA total of 3612 patients with ACS were included: 286 (7.9%) were diagnosed with AF, including 45 (1.2%) with paroxysmal AF, 227 (6.3%) with persistent/permanent AF and 14 (0.4%) with unclassified AF. Although 95.5% of patients with AF were at high risk (CHA2DS2-VASc score ≥2) of stroke, only 21.7% of them were discharged on OACs (10.5% received warfarin and 11.2% received non-vitamin K antagonist OACs). Patients with pre-admission use of OAC, a HAS-BLED score <3, with persistent/permanent AF were more likely to receive OAC treatment at discharge.ConclusionWe found that approximately 8% of patients who underwent PCI during ACS hospitalisation also demonstrated AF. Anticoagulant therapy was greatly underused. Patients with paroxysmal AF and an increased risk of bleeding were less likely to receive anticoagulant treatment. Further efforts should be made to increase the adherence to guideline recommendations for OACs.

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