Sleep architecture and the absence of trapezius muscle atonia in women with chronic whiplash-associated disorder: a pilot study

In this study, we report a case of a 50-year-old Japanese man who had chronic whiplash-associated disorder, hyperlipidaemia, hyperuricacidaemia, and mild liver dysfunction due to excessive alcohol intake. Recently, he developed mild tremor in his left hand. Initiation of clonazepam (0.5 mg once daily before bedtime) helped to gradually ameliorate the tremor. However, 13 days after clonazepam initiation, his liver function and lipid profiles aggravated, and his postprandial glucose level increased to 400 mg/dL. Clonazepam was stopped promptly, and at 7 days after discontinuation, the abnormal triglyceride levels, liver dysfunction, and glycometabolism improved without any other medical intervention. This case may provide information on cautious use of clonazepam. When clonazepam is used for patients with existing hyperlipidaemia and liver dysfunction, it may cause abnormal lipid profile, aggravate liver dysfunction, and lead to remarkable glucose elevation.

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Morphology of Cervical Spine Meniscoids in Individuals With Chronic Whiplash-Associated Disorder: A Case-Control Study

Journal of Orthopaedic and Sports Physical Therapy ◽

10.2519/jospt.2016.6702 ◽

2016 ◽

Vol 46 (10) ◽

pp. 902-910 ◽

Cited By ~ 8

Author(s):

Scott F. Farrell ◽

Peter G. Osmotherly ◽

Jon Cornwall ◽

Peter Lau ◽

Darren A. Rivett

Keyword(s):

Cervical Spine ◽

Case Control Study ◽

Case Control ◽

Chronic Whiplash ◽

Whiplash Associated Disorder ◽

Control Study

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Measures of central hyperexcitability in chronic whiplash associated disorder – A systematic review and meta-analysis

Manual Therapy ◽

10.1016/j.math.2012.07.009 ◽

2013 ◽

Vol 18 (2) ◽

pp. 111-117 ◽

Cited By ~ 47

Author(s):

Andrew M. Stone ◽

Bill Vicenzino ◽

Edwin C.W. Lim ◽

Michele Sterling

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Chronic Whiplash ◽

Whiplash Associated Disorder

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Correlations between Ratings of Pain, Disability and Impairment in Chronic Whiplash-Associated Disorder

Pain Research and Management ◽

10.1155/1997/987104 ◽

1997 ◽

Vol 2 (4) ◽

pp. 207-213 ◽

Cited By ~ 10

Author(s):

Howard Vernon

Keyword(s):

Rating Scale ◽

Neck Disability Index ◽

Physical Impairment ◽

P Value ◽

Pain Disability ◽

Pain Scores ◽

Disability Rating ◽

Chronic Whiplash ◽

Neck Disability ◽

Whiplash Associated Disorder

OBJECTIVE: To investigate the level of correlation among pain, disability and physical impairment scores in chronic whiplash-associated disorder patients.SUBJECTS: Adults with chronic whiplash-associated disorder referred for secondary independent assessment.METHODS: Forty-four subjects (16 males, 28 females) were included in the sample. Self-rated pain was measured on a five-point verbal rating scale. Self-rated disability was measured using the Neck Disability Index (NDI) and the Disability Rating Index (DRI). Physical impairment was measured as active cervical ranges of motion obtained with a cap goniometer. Descriptive statistics were reported and Pearson product moment correlations were obtained with the P value at 0.01.RESULTS: Mean ± SD age of the subjects was 36.4±8.7 years. Mean duration of complaint was 15.2±12.3 months. Mean pain score out of 5 was 2.5±1.2. Mean NDI and DRI scores were 23.2±9.3 out of 50 and 21.6±9.1 out of 48, respectively. These scores correlated very highly (r=0.89, P=0.0001). The average reduction of ranges of motion compared with published norms was approximately 25%. The correlations among ranges of motion, NDI, DRI and pain scores ranged from -0.32 to -0.66 (P<0.05 to P=0.0001). Age and duration of complaint correlated poorly with ranges of motion.CONCLUSIONS: The self-ratings of pain and disability obtained from these chronic whiplash-associated disorder sufferers appear to be consistent with, and correlate reasonably well with, levels of physical impairment. Physical impairment ratings do not appear to correlate well with duration, which suggests that factors related to pain and physical impairment may play an important role in the development of chronicity in whiplash-associated disorder.

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