Mitogen Response

2011 ◽  
Keyword(s):  
Mitogen Response

Relationship between mitogen response and aryl hydrocarbon hydroxylase in cultured human lymphocytes

Life Sciences ◽  
1978 ◽  
Vol 23 (3) ◽  
pp. 247-252 ◽  
Author(s):  
N. Prasad ◽  
R. Prasad ◽  
J.E. Harrell ◽  
J. Thornby ◽  
L.M. Fahr
Keyword(s):  
Human Lymphocytes ◽  
Aryl Hydrocarbon Hydroxylase ◽  
Aryl Hydrocarbon ◽  
Mitogen Response

The Influence of Dietary Protein Concentration and Energy Intake on Mitogen Response and Tumor Growth in Melanoma-Bearing Mice

1979 ◽  
Vol 109 (2) ◽  
pp. 353-359 ◽  
Author(s):  
Kent L. Erickson ◽  
M. Eric Gershwin ◽  
Nancy L. Canolty ◽  
David D. Eckels
Keyword(s):  
Tumor Growth ◽  
Energy Intake ◽  
Dietary Protein ◽  
Protein Concentration ◽  
Mitogen Response

scholarly journals High Proportion of Indeterminate Qua.jpegERON-TB Gold In-Tube Results in an Inpatient Population Is Related to Host Factors and Preanalytical Steps

2014 ◽  
Vol 1 (2) ◽  
Author(s):  
Valeria Fabre ◽  
Shmuel Shoham ◽  
Kathleen R. Page ◽  
Maunank Shah
Keyword(s):  
Skin Testing ◽  
Tertiary Care ◽  
Latent Tuberculosis ◽  
Host Factors ◽  
Inpatient Setting ◽  
Tuberculin Skin Testing ◽  
Sample Collection ◽  
Academic Center ◽  
Targeted Testing ◽  
Mitogen Response

Background.  Qua.jpegERON-TB Gold In-Tube test (QFT-GIT) can be used as an alternative to tuberculin skin testing (TST) for the targeted testing of latent tuberculosis. Due to many shortcomings with TST, QFT-GIT usage is increasing. QFT-GIT implementation in the inpatient setting remains unclear. Methods.  We retrospectively ide.jpegied patients admitted to a tertiary care academic center who received either a TST or a QFT-GIT in the 18 months prior to and after QFT-GIT implementation in March 2012. Risk factors associated with indeterminate results were evaluated. Results.  The proportion of inpatients receiving a test for tuberculosis infection doubled following QFT-GIT implementation (1.4% vs 2.9%). After QFT-GIT became available, 75% of tested people received a QFT-GIT and 25% received a TST. We found indeterminate test results in 19.8%. Independent predictors of indeterminate results were female sex (adjusted odds ratio [AOR], 1.64), lymphopenia (AOR, 2.21), hypoalbuminemia (AOR, 6.81) and sample collection by nonphlebotomists (AOR, 3.0, vs phlebotomists). Of patients who had indeterminate results, 42% had a subsequent indeterminate result on repeat testing. All indeterminate results were due to a low mitogen response. Conclusions.  QFT-GIT testing in the inpatient setting is associated with a high proportion of indeterminate results that is associated with host factors and preanalytical errors. Careful selection of patients to be tested and training on sample processing for QFT-GIT testing should be considered to decrease indeterminate results.

Mitogen response of peripheral blood and splenic lymphocytes and effect of 2-mercaptoethanol in tumor-bearing mice

1982 ◽  
Vol 12 (3) ◽  
Author(s):  
Yoshihiro Kikuchi ◽  
RaymondN. Hiramoto ◽  
VithalK. Ghanta
Keyword(s):  
Peripheral Blood ◽  
Splenic Lymphocytes ◽  
Tumor Bearing ◽  
Mitogen Response

Ontogeny of T-cell mitogen response in Lewis rats: II. Early appearance and loss of suppressor activity

1984 ◽  
Vol 8 (4) ◽  
pp. 907-919 ◽  
Author(s):  
Pamela A. Middleton ◽  
Wesley W. Bullock
Keyword(s):  
T Cell ◽  
Suppressor Activity ◽  
Lewis Rats ◽  
Early Appearance ◽  
Mitogen Response ◽  
Cell Mitogen

scholarly journals Mitogenic analysis of murine B-cell heterogeneity.

1978 ◽  
Vol 148 (1) ◽  
pp. 136-147 ◽  
Author(s):  
C Bona ◽  
A Yano ◽  
A Dimitriu ◽  
R G Miller
Keyword(s):  
B Cell ◽  
Dextran Sulfate ◽  
Water Soluble ◽  
Single Population ◽  
In Vitro Response ◽  
Mitogen Response ◽  
Cell Subpopulations ◽  
Specificity Pattern ◽  
Population Treatment

The B-cell mitogens lipopolysaccharide (LPS), Nocardia water-soluble mitogen (NWSM), and dextran sulfate (DxS) react with different subpopulations of B lymphocytes. Selective in vitro killing of cells responding to either LPS or NWSM has little effect on the in vitro response to the other mitogen, although the response to DxS is reduced in both cases. If, after selective in vitro killing, cells are injected into irradiated mice for 2-3 wk before measuring their in vitro mitogen responses, the same specificity pattern is seen. Thus, one is dealing with different B-cell subpopulations rather than different stages of maturation of a single population. Treatment with various alloantisera and complement before measuring the mitogen response to LPS and NWSM shows that (a) whereas all LPS response cells carry surface Ig, a subpopulation of NWSM responsive cells does not; (b) both LPS- and NWSM-responsive cells carry I-A antigens but might not I-E or I-J antigens; (c) all LPS-responsive cells carry I-C antigens, whereas approximately 25% of NWSM responsive cells do not: (d) there is a subpopulation of NWSM-responsive cells carrying neither surface Ig nor I-C antigens and resistant to anti-theta treatment.

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