Fetal distress and pH value of umbilical cord blood

Background: Even in low risk mothers, fetal acidosis occurs as in high risk groups. Aim of fetal monitoring is to detect early response to intrauterine hypoxia and prevent irreversible neurological damage and death. Objective of this study was to correlate the intrapartum fetal distress with the help of cardiotocography CTG with umbilical cord blood sampling.Methods: A total 100 consecutive patients attending the labor ward were studied. Immediately at birth, before the baby’s first breath and before delivery of the placenta, the umbilical cord blood was collected as per the standard guidelines laid down in the standard textbooks. Fetal acidosis was assessed by umbilical cord arterial blood pH. Fetal acidosis was considered when umbilical artery pH <7.2. Cardiotocography features were used to clinically diagnose fetal distress.Results: Most of the mothers were multigravida. They belonged to the age group of 20-25 years. Only 18% had abnormal CTG. Out of 50 mothers with normal vaginal delivery, all had normal CTG. Out of 43 mothers who were delivered by LSCS, no one had normal CTG, 25 had indeterminate CTG and 18 had abnormal CTG. As CTG became abnormal, proportion of mothers with the thick meconium increased. NICU admission proportion increased as CTG changed from normal to the abnormal. There was a significant association between the abnormal CTG and the umbilical cord blood pH being acidic.Conclusions: CTG is a simple test, easy to perform and can alert obstetrician for necessary interventions in case of an abnormal CTG. It can detect fetal distress in labor thus helping to reduce neonatal morbidity by early intervention in cases of abnormal tracing.

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Fetal distress is associated with intrauterine fetal hypoxia measured by umbilical cord blood erythropoietin (EPO)

International Journal of Gynecology & Obstetrics ◽

10.1016/s0020-7292(00)83079-9 ◽

2000 ◽

Vol 70 ◽

pp. B122-B122

Author(s):

Y. Nakaoka ◽

E. Hirata ◽

T. Murakami ◽

T. Matsuoka

Keyword(s):

Cord Blood ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Fetal Distress ◽

Fetal Hypoxia

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Ultrasonic characteristics and clinical significance of umbilical cord blood flow in acute fetal distress

Journal of Acute Disease ◽

10.1016/j.joad.2016.07.003 ◽

2016 ◽

Vol 5 (6) ◽

pp. 483-487 ◽

Cited By ~ 1

Author(s):

Wei Dai ◽

Yin Xu ◽

Xing-Wei Ma ◽

Li Zhang ◽

Ming-Juan Zhu

Keyword(s):

Blood Flow ◽

Cord Blood ◽

Clinical Significance ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Fetal Distress

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Relationship between immediate postpartum umbilical cord blood pH and fetal distress

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20160141 ◽

2016 ◽

pp. 113-119 ◽

Cited By ~ 2

Author(s):

Naina Kumar ◽

Aakanksha Suman ◽

Krutika Sawant

Keyword(s):

Cord Blood ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Fetal Distress ◽

Blood Ph

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Umbilical cord blood nucleated red cell count as a marker of perinatal asphyxia

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20181000 ◽

2018 ◽

Vol 5 (3) ◽

pp. 701

Author(s):

Manisha Chavan ◽

Pratibha M. Patil ◽

Vijay Bagali

Keyword(s):

Cord Blood ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Ph Value ◽

Perinatal Asphyxia ◽

Surrogate Marker ◽

Stage Ii ◽

Stage Iii ◽

Common Observation ◽

One Year

Background: Nucleated RBCs are a common observation in the circulating blood of newborn. Number of nRBC in cord blood and perinatal asphyxia shows good correlation. Perinatal asphyxia ranks as the second most important cause of neonatal death after infections accounting for about 30% mortality worldwide. Objective of the present study was designed to find the relation between umbilical cord blood nRBC count and perinatal asphyxia.Methods: The present one-year prospective case control study was carried out. A total of 100 babies divided into two groups of 50 each as cases and controls. Term babies with perinatal asphyxia were enrolled as cases and term babies without perinatal asphyxia born during same period were included as control.Results: The distribution of cord blood pH in cases showed maximum babies (80%) with pH value of <7 and 38% of the children were detected to have HIE stage II followed by 26% with stage I and 4% with stage III. At admission, 48 hours and 72 hours, significantly higher number of babies were found to have higher cord blood nRBC count (p<0.001) and the mean cord blood nRBC count was found to be significantly high at all the intervals (p <0.001). Comparison of mean cord blood nRBC count among cases in stage III was significantly high compared to stage II and I (p<0.001) at admission, 48 hours and 72 hours.Conclusions: Cord blood nRBC can be used as surrogate marker for asphyxia. The clearance of nRBC from the circulation may be of help in prognosticating the outcome of asphyxiated babies.

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Birth asphyxia measured by the pH value of the umbilical cord blood may predict an increased risk of attention deficit hyperactivity disorder

Acta Paediatrica ◽

10.1111/apa.13807 ◽

2017 ◽

Vol 106 (6) ◽

pp. 944-952 ◽

Cited By ~ 3

Author(s):

Susanne Hvolgaard Mikkelsen ◽

Jørn Olsen ◽

Bodil Hammer Bech ◽

Chunsen Wu ◽

Zeyan Liew ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Cord Blood ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Attention Deficit ◽

Ph Value ◽

Birth Asphyxia ◽

Hyperactivity Disorder ◽

Increased Risk

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The Effect of Maternal Pulmonary Function Test Parameters on Umbilical Cord Blood Gas and the Duration of Labor

Zeitschrift für Geburtshilfe und Neonatologie ◽

10.1055/a-1288-1765 ◽

2020 ◽

Author(s):

Melike Demir Çaltekin ◽

Taylan Onat ◽

Demet Aydogan Kırmızı ◽

Emre Baser ◽

Yavuz Selim İntepe ◽

...

Keyword(s):

Pulmonary Function ◽

Cord Blood ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Pulmonary Function Test ◽

Significant Positive Correlation ◽

Ph Value ◽

Apgar Scores ◽

Positive Correlation ◽

Function Test

Abstract Objective To evaluate the relationship between the maternal pulmonary function test (PFT) and the Apgar score of the newborn, umbilical cord blood (UCB) gas values and the duration of delivery. Material and Methods The present study included 41 volunteer nulliparous pregnant women who presented to our obstetrics clinic and PFTs were performed by using spirometry. Results A significant positive correlation was observed between 5th-minute Apgar scores and maternal FEV1 (forced expiratory volume in the first second) (lt), FEV1%, FVC (lt), FVC% (r=0.509, p=0.003; r=0.47, p=0.007; r=0.434, p=0.013; r=0.417, p=0.017; respectively). A significant positive correlation was observed between UCB pH value and maternal FEV1 (lt), FVC (lt) (r=0.515, p=0.003; r=0.351, p=0.049; respectively). Conclusion Our results showed that FEV1 and FVC values, which indicate maternal respiratory functions, may affect Apgar scores of the newborn and UCB gas values.

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Perinatal hypoxia and the risk of severe Molar-Incisor Hypomineralisation (MIH): a retrospective analysis of the pH value of umbilical arterial blood after birth

European Archives of Paediatric Dentistry ◽

10.1007/s40368-021-00622-5 ◽

2021 ◽

Author(s):

C. Hoberg ◽

C. Klein ◽

D. Klein ◽

C. Meller

Keyword(s):

Cesarean Section ◽

Cord Blood ◽

Umbilical Cord ◽

Umbilical Cord Blood ◽

Ph Value ◽

Control Group ◽

Molar Incisor Hypomineralisation ◽

Perinatal Hypoxia ◽

Arterial Blood ◽

Incisor Hypomineralisation

Abstract Purpose Molar-Incisor Hypomineralisation (MIH) remains a widespread developmental disorder of the teeth with a still largely unknown etiology. Perinatal events were blamed in previous studies for the development of MIH. The aim of the present study was to evaluate the influence of perinatal hypoxia—determined by the pH value of the umbilical cord blood—and to investigate its correlation with severe MIH retrospectively. In addition, cesarean section was recorded as differentiation variable. Methods A total number of 138 children (mean age 8.0 years ± 1.7), who were treated for severe MIH in a dental office in Berlin between the years 2008 and 2019, were included in the study. The control group was comprised of patients with the same date of birth (44 children, mean age 7.7 years ± 1.7). Information on the pH value of the arterial blood from the umbilical cord taken immediately after birth, whose recording is mandatory in Germany, was received from the parents by letter survey requesting the entries from the German Child Health Booklet. Results In the group of the male children born without cesarean section, the pH value of the control group was significantly lower (7.19 ± 0.09) than the pH value of the MIH group (7.27 ± 0.07, p = 0.0008). In female children born with or without cesarean section as well as in male children born by cesarean section there were no significant differences between the MIH and control group. Conclusions No significant association between MIH and the pH value of the umbilical cord blood or birth by cesarean section could be found in the examined patient population.

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